norfluoxetine has been researched along with Depression, Involutional in 5 studies
norfluoxetine: metabolite of fluoxetine; RN given refers to parent cpd without isomeric designation
Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Blood from pregnant women taking fluoxetine (n = 9), during pregnancy was sampled in the third trimester and at delivery (maternal and cord venous blood), and from the infants 48 h after delivery." | 7.73 | Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding. ( Fitzgerald, C; Grunau, RE; Kent, N; Kim, J; Misri, S; Oberlander, TF; Riggs, KW; Rurak, DW, 2006) |
| "To add to the limited data on the clinical pharmacology of antidepressants during pregnancy, we examined the dose-corrected chiral and racemic levels (level/dose) of fluoxetine (FLX) and norfluoxetine (NorFLX) during pregnancy and early postpartum." | 5.14 | Disposition of chiral and racemic fluoxetine and norfluoxetine across childbearing. ( Helsel, JC; Luther, JF; Perel, JM; Sit, D; Wisner, KL; Wisniewski, SR, 2010) |
| "Blood from pregnant women taking fluoxetine (n = 9), during pregnancy was sampled in the third trimester and at delivery (maternal and cord venous blood), and from the infants 48 h after delivery." | 3.73 | Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding. ( Fitzgerald, C; Grunau, RE; Kent, N; Kim, J; Misri, S; Oberlander, TF; Riggs, KW; Rurak, DW, 2006) |
| " High inter-individual variability in serum concentrations of the active moiety of FLX at each dosage level was observed and no relationship between serum concentration and clinical outcome was found." | 2.77 | Therapeutic drug monitoring of children and adolescents treated with fluoxetine. ( Burger, R; Egberts, K; Fegert, JM; Gerlach, M; Kliegl, K; Koelch, M; Ludolph, AG; Mehler-Wex, C; Pfalzer, AK; Rothenhöfer, S; Stingl, J; Taurines, R, 2012) |
| "Only 30% of major depressive disorder (MDD) patients achieve complete remission with a serotonergic antidepressant (selective serotonin reuptake inhibitor)." | 1.43 | Evaluation of interleukin-6 and serotonin as biomarkers to predict response to fluoxetine. ( Manoharan, A; Muthuramalingam, A; Paul, A; Rajkumar, RP; Shewade, DG; Sundaram, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manoharan, A | 1 |
| Rajkumar, RP | 1 |
| Shewade, DG | 1 |
| Sundaram, R | 1 |
| Muthuramalingam, A | 1 |
| Paul, A | 1 |
| Sit, D | 1 |
| Perel, JM | 1 |
| Luther, JF | 1 |
| Wisniewski, SR | 1 |
| Helsel, JC | 1 |
| Wisner, KL | 1 |
| Koelch, M | 1 |
| Pfalzer, AK | 1 |
| Kliegl, K | 1 |
| Rothenhöfer, S | 1 |
| Ludolph, AG | 1 |
| Fegert, JM | 1 |
| Burger, R | 1 |
| Mehler-Wex, C | 1 |
| Stingl, J | 1 |
| Taurines, R | 1 |
| Egberts, K | 1 |
| Gerlach, M | 1 |
| Kim, J | 1 |
| Riggs, KW | 1 |
| Misri, S | 1 |
| Kent, N | 1 |
| Oberlander, TF | 1 |
| Grunau, RE | 1 |
| Fitzgerald, C | 1 |
| Rurak, DW | 1 |
| Brunswick, DJ | 1 |
| Amsterdam, JD | 1 |
| Fawcett, J | 1 |
| Quitkin, FM | 1 |
| Reimherr, FW | 1 |
| Rosenbaum, JF | 1 |
| Beasley, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antidepressant Use During Pregnancy[NCT00279370] | 283 participants (Actual) | Observational | 1999-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for norfluoxetine and Depression, Involutional
| Article | Year |
|---|---|
Disposition of chiral and racemic fluoxetine and norfluoxetine across childbearing.
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Female; Fluoxetine; Hum | 2010 |
Therapeutic drug monitoring of children and adolescents treated with fluoxetine.
Topics: Adolescent; Age Factors; Child; Cohort Studies; Depressive Disorder, Major; Dose-Response Relationsh | 2012 |
Fluoxetine and norfluoxetine plasma concentrations during relapse-prevention treatment.
Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedu | 2002 |
2 other studies available for norfluoxetine and Depression, Involutional
| Article | Year |
|---|---|
Evaluation of interleukin-6 and serotonin as biomarkers to predict response to fluoxetine.
Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Chromatography, Liquid; Depressive Disord | 2016 |
Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding.
Topics: Adult; Aging; Antidepressive Agents, Second-Generation; Breast Feeding; Depressive Disorder, Major; | 2006 |