norfloxacin has been researched along with Urethritis in 16 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Urethritis: Inflammation involving the URETHRA. Similar to CYSTITIS, clinical symptoms range from vague discomfort to painful urination (DYSURIA), urethral discharge, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Norfloxacin (NOR) was given to 37 patients affected by urethritis due to Chlamydia trachomatis (CT), as demonstrated by clinical findings and fluorescent monoclonal antibody in urethral swab." | 9.06 | [A clinical study on the use of norfloxacin in the therapy of urethritis caused by Chlamydia trachomatis]. ( Cespa, M; Concia, E; Cruciani, M; Donadini, A; Gusmitta, A; Rabbiosi, G, 1990) |
| "Fifty six males with gonococcal urethritis were administered 600 mg of norfloxacin (NFLX) daily for 7 days, before the effects were examined." | 9.06 | [Treatment of gonococcal urethritis with norfloxacin]. ( Asaka, H; Asano, H; Fukatsu, H; Mitsuya, H; Murase, T; Obata, K; Okamura, K; Otani, S; Segawa, A; Yoshida, K, 1989) |
| "Thirty patients with acute urethritis were treated with short-term administration of norfloxacin." | 9.06 | [Clinical effectiveness of short-term administration of norfloxacin in acute urethritis]. ( Fukui, I; Goto, S; Kihara, K; Mizuo, T; Oshima, H, 1986) |
| "Fifteen male outpatients with uncomplicated gonococcal urethritis were treated by a single oral dose of norfloxacin (800 mg)." | 7.67 | Clinical trial of norfloxacin in the treatment of uncomplicated gonococcal urethritis: preliminary report. ( Cristiano, P, 1989) |
| "Thirty male patients with gonorrheal urethritis were treated with norfloxacin (NFLX) at our urological ward between May and July, 1984, and clinically evaluated." | 7.67 | [Bacteriological and clinical evaluation of norfloxacin in male gonorrheal urethritis]. ( Okazaki, T, 1987) |
| "Norfloxacin, a new quinolinecarboxylic acid derivative, was administered to 30 male patients with gonococcal urethritis at a daily dose of 600 mg for 7-21 days." | 7.67 | [Clinical evaluation of norfloxacin in gonococcal urethritis]. ( Jinbo, S; Mashimo, T; Miki, M; Yamanaka, H, 1986) |
| " Ciprofloxacin is effective in single dosage against urogenital gonococcal infections, and probably also against rectal and pharyngeal infections." | 6.37 | Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis. ( Oriel, JD, 1986) |
| "Norfloxacin has some activity in vitro against Chlamydia trachomatis and Ureaplasma urealyticum, although not at levels attainable in serum." | 5.27 | Failure of norfloxacin to eradicate Chlamydia trachomatis in nongonococcal urethritis. ( Bowie, WR; Sibau, L; Willetts, V, 1986) |
| "Norfloxacin (NOR) was given to 37 patients affected by urethritis due to Chlamydia trachomatis (CT), as demonstrated by clinical findings and fluorescent monoclonal antibody in urethral swab." | 5.06 | [A clinical study on the use of norfloxacin in the therapy of urethritis caused by Chlamydia trachomatis]. ( Cespa, M; Concia, E; Cruciani, M; Donadini, A; Gusmitta, A; Rabbiosi, G, 1990) |
| "Fifty six males with gonococcal urethritis were administered 600 mg of norfloxacin (NFLX) daily for 7 days, before the effects were examined." | 5.06 | [Treatment of gonococcal urethritis with norfloxacin]. ( Asaka, H; Asano, H; Fukatsu, H; Mitsuya, H; Murase, T; Obata, K; Okamura, K; Otani, S; Segawa, A; Yoshida, K, 1989) |
| "Thirty patients with acute urethritis were treated with short-term administration of norfloxacin." | 5.06 | [Clinical effectiveness of short-term administration of norfloxacin in acute urethritis]. ( Fukui, I; Goto, S; Kihara, K; Mizuo, T; Oshima, H, 1986) |
| "Fifteen male outpatients with uncomplicated gonococcal urethritis were treated by a single oral dose of norfloxacin (800 mg)." | 3.67 | Clinical trial of norfloxacin in the treatment of uncomplicated gonococcal urethritis: preliminary report. ( Cristiano, P, 1989) |
| "Thirty male patients with gonorrheal urethritis were treated with norfloxacin (NFLX) at our urological ward between May and July, 1984, and clinically evaluated." | 3.67 | [Bacteriological and clinical evaluation of norfloxacin in male gonorrheal urethritis]. ( Okazaki, T, 1987) |
| "Following a summary of the main bacteriological and pharmacokinetic properties of this new quinolone derivative, the author reviews the results obtained with pefloxacine in the treatment of urinary tract infection, gonococcal urethritis, and bronchopulmonary, surgical, gynaecological, bone, soft tissue, neuromeningeal and ENT infections." | 3.67 | [Pefloxacin: evaluation and clinical prospects]. ( Modaï, J, 1986) |
| "Norfloxacin, a new quinolinecarboxylic acid derivative, was administered to 30 male patients with gonococcal urethritis at a daily dose of 600 mg for 7-21 days." | 3.67 | [Clinical evaluation of norfloxacin in gonococcal urethritis]. ( Jinbo, S; Mashimo, T; Miki, M; Yamanaka, H, 1986) |
| "We studied the basic and clinical effects of norfloxacin (NFLX) in 120 patients with gonococcal infections (110 men with urethritis and 10 women with cervicitis)--all residents at Sapporo City; and epidemiologically analyzed the sources of their infections." | 3.67 | [Epidemiologic and therapeutic study on gonococcal infections--clinical efficacy of norfloxacin]. ( Gohro, T; Henmi, I; Hirose, T; Igawa, K; Inoke, T; Kumamoto, Y; Sakai, S; Tabata, S; Tazuki, J; Tsunekawa, T, 1986) |
| " Ciprofloxacin is effective in single dosage against urogenital gonococcal infections, and probably also against rectal and pharyngeal infections." | 2.37 | Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis. ( Oriel, JD, 1986) |
| "Norfloxacin has some activity in vitro against Chlamydia trachomatis and Ureaplasma urealyticum, although not at levels attainable in serum." | 1.27 | Failure of norfloxacin to eradicate Chlamydia trachomatis in nongonococcal urethritis. ( Bowie, WR; Sibau, L; Willetts, V, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meier-Ewert, H | 1 |
| Weil, G | 1 |
| Millott, G | 1 |
| Crider, SR | 1 |
| Colby, SD | 1 |
| Miller, LK | 1 |
| Harrison, WO | 1 |
| Kerbs, SB | 1 |
| Berg, SW | 1 |
| Jain, SK | 1 |
| Kulkarni, MG | 2 |
| Banker, DD | 1 |
| Tanaka, M | 1 |
| Kumazawa, J | 1 |
| Matsumoto, T | 1 |
| Kobayashi, I | 1 |
| Pai, A | 1 |
| Koppikar, GV | 1 |
| Rabbiosi, G | 1 |
| Donadini, A | 1 |
| Cespa, M | 1 |
| Concia, E | 1 |
| Cruciani, M | 1 |
| Gusmitta, A | 1 |
| Mitsuya, H | 1 |
| Asaka, H | 1 |
| Segawa, A | 1 |
| Fukatsu, H | 1 |
| Otani, S | 1 |
| Yoshida, K | 1 |
| Okamura, K | 1 |
| Murase, T | 1 |
| Asano, H | 1 |
| Obata, K | 1 |
| Cristiano, P | 1 |
| Okazaki, T | 1 |
| Modaï, J | 1 |
| Oriel, JD | 1 |
| Kihara, K | 1 |
| Mizuo, T | 1 |
| Fukui, I | 1 |
| Oshima, H | 1 |
| Goto, S | 1 |
| Miki, M | 1 |
| Jinbo, S | 1 |
| Mashimo, T | 1 |
| Yamanaka, H | 1 |
| Bowie, WR | 1 |
| Willetts, V | 1 |
| Sibau, L | 1 |
| Sakai, S | 1 |
| Kumamoto, Y | 1 |
| Tsunekawa, T | 1 |
| Hirose, T | 1 |
| Tabata, S | 1 |
| Gohro, T | 1 |
| Inoke, T | 1 |
| Igawa, K | 1 |
| Tazuki, J | 1 |
| Henmi, I | 1 |
| Holmes, B | 1 |
| Brogden, RN | 1 |
| Richards, DM | 1 |
2 reviews available for norfloxacin and Urethritis
| Article | Year |
|---|---|
Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis.
Topics: 4-Quinolones; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chlamydia Infections; Chlamydia | 1986 |
Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Topics: Antifungal Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial | 1985 |
3 trials available for norfloxacin and Urethritis
| Article | Year |
|---|---|
[A clinical study on the use of norfloxacin in the therapy of urethritis caused by Chlamydia trachomatis].
Topics: Adolescent; Adult; Chlamydia Infections; Chlamydia trachomatis; Humans; Male; Norfloxacin; Time Fact | 1990 |
[Treatment of gonococcal urethritis with norfloxacin].
Topics: Adult; Clinical Trials as Topic; Gonorrhea; Humans; Male; Middle Aged; Multicenter Studies as Topic; | 1989 |
[Clinical effectiveness of short-term administration of norfloxacin in acute urethritis].
Topics: Acute Disease; Adult; Drug Administration Schedule; Gonorrhea; Humans; Male; Middle Aged; Norfloxaci | 1986 |
11 other studies available for norfloxacin and Urethritis
| Article | Year |
|---|---|
In vitro activity of norfloxacin against Chlamydia trachomatis.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Humans; Nalidixic Acid; Norfloxacin; Species Specifici | 1983 |
Treatment of penicillin-resistant Neisseria gonorrhoeae with oral norfloxacin.
Topics: Administration, Oral; Anti-Bacterial Agents; Drug Tolerance; Gonorrhea; Humans; Male; Nalidixic Acid | 1984 |
Antibiotic susceptibility pattern of gonococcal isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria | 1994 |
High prevalence of Neisseria gonorrhoeae strains with reduced susceptibility to fluoroquinolones in Japan.
Topics: Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbi | 1994 |
Antibiotics sensitivity pattern of N. gonorrhoeae with special emphasis on norfloxacin and ciprofloxacin.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Gonorrhea; Humans; Ma | 1999 |
Clinical trial of norfloxacin in the treatment of uncomplicated gonococcal urethritis: preliminary report.
Topics: Adult; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Pen | 1989 |
[Bacteriological and clinical evaluation of norfloxacin in male gonorrheal urethritis].
Topics: Adolescent; Adult; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Norfl | 1987 |
[Pefloxacin: evaluation and clinical prospects].
Topics: Bacterial Infections; Evaluation Studies as Topic; Female; Humans; Lung Diseases; Male; Meningitis; | 1986 |
[Clinical evaluation of norfloxacin in gonococcal urethritis].
Topics: Adult; Drug Administration Schedule; Drug Evaluation; Gonorrhea; Humans; Male; Middle Aged; Norfloxa | 1986 |
Failure of norfloxacin to eradicate Chlamydia trachomatis in nongonococcal urethritis.
Topics: Adolescent; Adult; Chlamydia Infections; Chlamydia trachomatis; Humans; Male; Middle Aged; Mycoplasm | 1986 |
[Epidemiologic and therapeutic study on gonococcal infections--clinical efficacy of norfloxacin].
Topics: Adolescent; Adult; Aged; Chlamydia Infections; Chlamydia trachomatis; Drug Evaluation; Drug Resistan | 1986 |