norfloxacin has been researched along with Stevens-Johnson Syndrome in 2 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 77-year-old male who had suffered from an upper respiratory infection and had been given Norfloxacin (NFLX) on May 2, 1990, developed generalized erythema which did not subside with prednisolone." | 7.68 | [Norfloxacin-induced infectious mononucleosis (IM)-like syndrome with Stevens-Johnson syndrome]. ( Kubo-Shimasaki, A; Tatsumi, E; Yamaguchi, N; Yoneda, N; Yoshimoto, K, 1992) |
| " A MEDLINE search (1966-February 2005) revealed no reports of toxic epidermal necrolysis, but one incidence of Stevens-Johnson syndrome due to norfloxacin therapy." | 3.73 | Norfloxacin-induced toxic epidermal necrolysis. ( Filiz, EE; Inanir, I; Ozturkcan, S; Sahin, MT, 2005) |
| "A 77-year-old male who had suffered from an upper respiratory infection and had been given Norfloxacin (NFLX) on May 2, 1990, developed generalized erythema which did not subside with prednisolone." | 3.68 | [Norfloxacin-induced infectious mononucleosis (IM)-like syndrome with Stevens-Johnson syndrome]. ( Kubo-Shimasaki, A; Tatsumi, E; Yamaguchi, N; Yoneda, N; Yoshimoto, K, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sahin, MT | 1 |
| Ozturkcan, S | 1 |
| Inanir, I | 1 |
| Filiz, EE | 1 |
| Kubo-Shimasaki, A | 1 |
| Yoshimoto, K | 1 |
| Tatsumi, E | 1 |
| Yoneda, N | 1 |
| Yamaguchi, N | 1 |
2 other studies available for norfloxacin and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Norfloxacin-induced toxic epidermal necrolysis.
Topics: Adult; Humans; Male; Norfloxacin; Stevens-Johnson Syndrome | 2005 |
[Norfloxacin-induced infectious mononucleosis (IM)-like syndrome with Stevens-Johnson syndrome].
Topics: Aged; Drug Hypersensitivity; Erythema; Fatigue Syndrome, Chronic; Humans; Male; Norfloxacin; Stevens | 1992 |