norfloxacin has been researched along with Pyrexia in 10 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of a combination regimen using norfloxacin (NFLX) and amphotericin B (AMPH-B) for prevention of infections in patients with acute leukemia being treated by remission-induction chemotherapy in a randomized, controlled trial was studied." | 9.07 | Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B. ( Dan, K; Nomura, T; Yamada, T, 1993) |
| "Fever was induced and maintained for 12 h by injecting Escherichia coli endotoxin (0." | 5.29 | The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats. ( Jha, K; Roy, BK; Singh, RC, 1996) |
| "The effect of a combination regimen using norfloxacin (NFLX) and amphotericin B (AMPH-B) for prevention of infections in patients with acute leukemia being treated by remission-induction chemotherapy in a randomized, controlled trial was studied." | 5.07 | Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B. ( Dan, K; Nomura, T; Yamada, T, 1993) |
| "More patients receiving ciprofloxacin did not develop fever during neutropenia and did not receive antibiotics (34%) compared with those receiving norfloxacin (25%) (P = 0." | 5.07 | Prevention of bacterial infection in neutropenic patients with hematologic malignancies. A randomized, multicenter trial comparing norfloxacin with ciprofloxacin. The GIMEMA Infection Program. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto. ( , 1991) |
| " The treatment of 37 initial febrile episodes (12 cases of septicemia, 7 infectious sites and 38 cases of fever of unknown origin) in 33 neutropenic patients (PMN leucocytes less than 500/mm3) using the combination of a third generation cephalosporin (cefotaxime or ceftazidime) and a new quinolone (pefloxacin) resulted in an 86% immediate success rate (32 cases/37)." | 5.06 | [Combination of a 3d-generation cephalosporin (cefotaxime or ceftazidime) and a new quinolone (pefloxacine) in the treatment of febrile episodes in neutropenic diseases (37 cases)]. ( Bielefeld, P; Caillot, D; Guy, H; Kazmierczak, A; Portier, H; Solary, E, 1987) |
| "In the patient described here, norfloxacin induced a generalized erythematous subcorneal pustular drug eruption associated with photosensitivity and fever, proven by challenge." | 3.67 | The subcorneal pustular drug eruption: an example induced by norfloxacin. ( Shelley, ED; Shelley, WB, 1988) |
| "Norfloxacin 400 mg ? 2 was given for 3 days as prophylaxis starting just before or within 10 min of biopsy." | 1.37 | Febrile reactions after transrectal ultrasound-guided prostatic biopsy: a retrospective study. ( Claesson, BE; Hedelin, H; Wilpart, A, 2011) |
| "Fever was induced and maintained for 12 h by injecting Escherichia coli endotoxin (0." | 1.29 | The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats. ( Jha, K; Roy, BK; Singh, RC, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hedelin, H | 1 |
| Claesson, BE | 1 |
| Wilpart, A | 1 |
| Yamada, T | 1 |
| Dan, K | 1 |
| Nomura, T | 1 |
| Broun, ER | 1 |
| Wheat, JL | 1 |
| Kneebone, PH | 1 |
| Sundblad, K | 1 |
| Hromas, RA | 1 |
| Tricot, G | 1 |
| Jha, K | 1 |
| Roy, BK | 1 |
| Singh, RC | 1 |
| Sundman, K | 1 |
| Arneborn, P | 1 |
| Blad, L | 1 |
| Sjöberg, L | 1 |
| Vikerfors, T | 1 |
| Albitar, S | 1 |
| Genin, R | 1 |
| Fen-Chong, M | 1 |
| Schohn, D | 1 |
| Riviere, JP | 1 |
| Serveaux, MO | 1 |
| Chuet, C | 1 |
| D'Antonio, D | 1 |
| Iacone, A | 1 |
| Fioritoni, G | 1 |
| Betti, S | 1 |
| Dell'Isola, M | 1 |
| Quaglietta, AM | 1 |
| Accorsi, P | 1 |
| Pantalone, V | 1 |
| Recchia, A | 1 |
| Piergallini, A | 1 |
| Guy, H | 1 |
| Caillot, D | 1 |
| Solary, E | 1 |
| Bielefeld, P | 1 |
| Portier, H | 1 |
| Kazmierczak, A | 1 |
| Shelley, ED | 1 |
| Shelley, WB | 1 |
6 trials available for norfloxacin and Pyrexia
| Article | Year |
|---|---|
Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B.
Topics: Administration, Oral; Adult; Amphotericin B; Antineoplastic Agents; Bacterial Infections; Drug Combi | 1993 |
Randomized trial of the addition of gram-positive prophylaxis to standard antimicrobial prophylaxis for patients undergoing autologous bone marrow transplantation.
Topics: Acyclovir; Adult; Bacteremia; Bone Marrow Transplantation; Female; Fever; Fluconazole; Gram-Positive | 1994 |
One bolus dose of gentamicin and early oral therapy versus cefotaxime and subsequent oral therapy in the treatment of febrile urinary tract infection.
Topics: Adult; Aged; Aged, 80 and over; Cefotaxime; Drug Therapy, Combination; Female; Fever; Gentamicins; H | 1997 |
Comparison of norfloxacin and pefloxacin in the prophylaxis of bacterial infection in neutropenic cancer patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bacteremia; Bacterial Infections; Female; Fever; Hum | 1992 |
Prevention of bacterial infection in neutropenic patients with hematologic malignancies. A randomized, multicenter trial comparing norfloxacin with ciprofloxacin. The GIMEMA Infection Program. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Female; Fever; | 1991 |
[Combination of a 3d-generation cephalosporin (cefotaxime or ceftazidime) and a new quinolone (pefloxacine) in the treatment of febrile episodes in neutropenic diseases (37 cases)].
Topics: Agranulocytosis; Anti-Infective Agents; Cefotaxime; Ceftazidime; Drug Evaluation; Drug Therapy, Comb | 1987 |
4 other studies available for norfloxacin and Pyrexia
| Article | Year |
|---|---|
Febrile reactions after transrectal ultrasound-guided prostatic biopsy: a retrospective study.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy; Drug Resistance, Bacterial; Escherichia coli; | 2011 |
The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats.
Topics: Analysis of Variance; Animals; Drug Interactions; Endotoxins; Escherichia coli; Female; Fever; Goats | 1996 |
The febrile patient presenting with acute renal failure and enlarged kidneys--another mode of presentation of malakoplakia.
Topics: Acute Kidney Injury; Aged; Anti-Infective Agents; Escherichia coli Infections; Fever; Humans; Kidney | 1997 |
The subcorneal pustular drug eruption: an example induced by norfloxacin.
Topics: Biopsy; Drug Eruptions; Fever; Humans; Male; Middle Aged; Norfloxacin; Photosensitivity Disorders; S | 1988 |