Page last updated: 2024-11-01

norfloxacin and Prostatitis

norfloxacin has been researched along with Prostatitis in 16 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Prostatitis: Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment.

Research Excerpts

ExcerptRelevanceReference
"We treated 15 men who had chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin with 400 mg."7.68The efficacy of norfloxacin in the treatment of chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin. ( Darras, FS; Schaeffer, AJ, 1990)
"The clinical efficacy of norfloxacin (NFLX) was evaluated in 74 patients having chronic prostatitis with the subjective symptoms suggesting the inflammations of prostate and more than five white bloodcells (WBCs)/hpf in their prostatic secretions (EPS)."7.67[The therapeutic effect of norfloxacin on chronic prostatitis]. ( Gouro, T; Henmi, I; Igawa, K; Kadono, M; Kumamoto, Y; Maekwa, S; Oguma, K; Okayama, S; Sakai, S; Tsukamoto, T, 1987)
" Norfloxacin, a new quinolone antibacterial agent particularly active in urinary tract infections, gave excellent results (400 mg every 12 h for 10 days) in the treatment of chronic-relapsing prostatitis in a group of 20 patients."7.67Norfloxacin in prostatitis: correlation between HPLC tissue concentrations and clinical results. ( Bologna, M; Carlucci, G; Flammini, D; Forchetti, CM; Vaggi, L, 1985)
"Norfloxacin is a lipid-soluble weak organic acid bound to plasma proteins to a low extent."6.66Norfloxacin versus co-trimoxazole in the treatment of recurring urinary tract infections in men. ( Cook, T; Hoagland, VL; Sabbaj, J, 1986)
"We treated 15 men who had chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin with 400 mg."3.68The efficacy of norfloxacin in the treatment of chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin. ( Darras, FS; Schaeffer, AJ, 1990)
"The clinical efficacy of norfloxacin (NFLX) was evaluated in 74 patients having chronic prostatitis with the subjective symptoms suggesting the inflammations of prostate and more than five white bloodcells (WBCs)/hpf in their prostatic secretions (EPS)."3.67[The therapeutic effect of norfloxacin on chronic prostatitis]. ( Gouro, T; Henmi, I; Igawa, K; Kadono, M; Kumamoto, Y; Maekwa, S; Oguma, K; Okayama, S; Sakai, S; Tsukamoto, T, 1987)
" Norfloxacin, a new quinolone antibacterial agent particularly active in urinary tract infections, gave excellent results (400 mg every 12 h for 10 days) in the treatment of chronic-relapsing prostatitis in a group of 20 patients."3.67Norfloxacin in prostatitis: correlation between HPLC tissue concentrations and clinical results. ( Bologna, M; Carlucci, G; Flammini, D; Forchetti, CM; Vaggi, L, 1985)
"Norfloxacin is a lipid-soluble weak organic acid bound to plasma proteins to a low extent."2.66Norfloxacin versus co-trimoxazole in the treatment of recurring urinary tract infections in men. ( Cook, T; Hoagland, VL; Sabbaj, J, 1986)
" We employed a rat model of chronic bacterial prostatitis to investigate any pharmacokinetic differences that may exist between uninflamed and inflamed prostate glands."1.29Antibiotic pharmacokinetics in the inflamed prostate. ( Ceri, H; Clark, J; Downey, J; Nickel, JC; Olson, M, 1995)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's3 (18.75)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glick, R1
Epstein, DS1
Aponso, DT1
Peppas, T1
Petrikkos, G1
Deliganni, V1
Zoumboulis, P1
Koulentianos, E1
Giamarellou, H1
Bologna, M2
Vaggi, L2
Forchetti, CM2
Martini, E1
Jensen, KM1
Madsen, PO1
Nickel, JC1
Downey, J1
Clark, J1
Ceri, H1
Olson, M1
Schaeffer, AJ1
Darras, FS1
Morikawa, M1
Tokunaka, S1
Yachiku, S1
Yamauchi, K1
Wakabayashi, A1
Inagaki, N1
Nishihara, M1
Yamaguchi, S1
Boerema, JB1
Bischoff, W1
Borsa, F1
Humbert, G1
Sheikh, MA1
Naqvi, SA1
Sabbaj, J1
Hoagland, VL1
Cook, T1
Dan, M1
Golomb, J1
Gorea, A1
Lindner, A1
Berger, SA1
Kumamoto, Y1
Tsukamoto, T1
Sakai, S1
Gouro, T1
Maekwa, S1
Oguma, K1
Henmi, I1
Igawa, K1
Kadono, M1
Okayama, S1
Denis, B1
Wauters, G1
Wese, F1
Van Cangh, PJ1
Flammini, D1
Carlucci, G1

Trials

1 trial available for norfloxacin and Prostatitis

ArticleYear
Norfloxacin versus co-trimoxazole in the treatment of recurring urinary tract infections in men.
    Scandinavian journal of infectious diseases. Supplementum, 1986, Volume: 48

    Topics: Anti-Infective Agents, Urinary; Bacteria; Drug Combinations; Humans; Male; Microbial Sensitivity Tes

1986

Other Studies

15 other studies available for norfloxacin and Prostatitis

ArticleYear
Spontaneous bilateral quadriceps tendon rupture associated with norfloxacin.
    Internal medicine journal, 2015, Volume: 45, Issue:12

    Topics: Accidental Falls; Aged; Anti-Bacterial Agents; Humans; Knee Injuries; Male; Norfloxacin; Prostatitis

2015
Efficacy of long-term therapy with norfloxacin in chronic bacterial prostatitis.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Humans; Male; Mi

1989
Bactericidal intraprostatic concentrations of norfloxacin.
    Lancet (London, England), 1983, Jul-30, Volume: 2, Issue:8344

    Topics: Anti-Infective Agents; Humans; Male; Nalidixic Acid; Norfloxacin; Prostate; Prostatitis

1983
Distribution of quinoline carboxylic acid derivatives in the dog prostate.
    The Prostate, 1983, Volume: 4, Issue:4

    Topics: 4-Quinolones; Administration, Oral; Animals; Anti-Infective Agents; Dogs; Drug Evaluation, Preclinic

1983
Antibiotic pharmacokinetics in the inflamed prostate.
    The Journal of urology, 1995, Volume: 153, Issue:2

    Topics: Animals; Bacterial Infections; Chronic Disease; Male; Norfloxacin; Prostatitis; Rats; Rats, Sprague-

1995
The efficacy of norfloxacin in the treatment of chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin.
    The Journal of urology, 1990, Volume: 144, Issue:3

    Topics: Carbenicillin; Chronic Disease; Escherichia coli Infections; Follow-Up Studies; Humans; Male; Middle

1990
[The therapeutic effect of norfloxacin on chronic prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1990, Volume: 36, Issue:10

    Topics: Adult; Aged; Bacterial Infections; Chronic Disease; Drug Evaluation; Humans; Leukocyte Count; Male;

1990
New 4-quinolones in the treatment of urinary tract infections.
    Pharmaceutisch weekblad. Scientific edition, 1986, Feb-21, Volume: 8, Issue:1

    Topics: Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Combinations; Humans; Male; Norfloxacin; Pefloxa

1986
[Norfloxacin treatment of acute cystitis in the female and bacterial prostatitis].
    Fortschritte der Medizin, 1985, Feb-28, Volume: 103, Issue:8

    Topics: Adult; Anti-Infective Agents, Urinary; Bacterial Infections; Cystitis; Female; Humans; Male; Microbi

1985
[Treatment of urinary tract infections].
    La Revue du praticien, 1985, Mar-11, Volume: 35, Issue:15

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Chlamydia Infections; Female; Humans; Lactams

1985
A study of the use of norfloxacin in prostatitis.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Adult; Escherichia coli Infections; Humans; Male; Norfloxacin; Prostatitis; Staphylococcal Infection

1987
Penetration of norfloxacin into human prostatic tissue following single-dose oral administration.
    Chemotherapy, 1987, Volume: 33, Issue:4

    Topics: Aged; Aged, 80 and over; Humans; Male; Middle Aged; Norfloxacin; Prostate; Prostatitis

1987
[The therapeutic effect of norfloxacin on chronic prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:3

    Topics: Adult; Aged; Chronic Disease; Drug Resistance, Microbial; Gram-Negative Bacteria; Humans; Male; Micr

1987
Intraprostatic bactericidal concentrations of Norfloxacin.
    Acta urologica Belgica, 1986, Volume: 54, Issue:3

    Topics: Administration, Oral; Aged; Humans; Male; Middle Aged; Norfloxacin; Prostate; Prostatitis

1986
Norfloxacin in prostatitis: correlation between HPLC tissue concentrations and clinical results.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:2

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Humans; Kinetics; Male; Middle Ag

1985