Page last updated: 2024-11-01

norfloxacin and Peritonitis

norfloxacin has been researched along with Peritonitis in 65 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.

Research Excerpts

ExcerptRelevanceReference
"Once weekly ciprofloxacin was as effective as daily norfloxacin for the prevention of SBP in cirrhotic patients with ascites."9.27Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial. ( Jang, JY; Jung, YK; Kim, BI; Kim, HS; Kim, YS; Lee, YR; Park, SY; Seo, YS; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2018)
"Two hundred and sixty two cirrhotic patients with ascites and a previous episode of SBP were assigned randomly to receive either 1200 mg rifaximin or 400 mg of norfloxacin daily for 6 months."9.22Randomized-controlled trial of rifaximin versus norfloxacin for secondary prophylaxis of spontaneous bacterial peritonitis. ( Abd-Elsalam, S; Abo Ali, L; Elfert, A; Ibrahim, S; Soliman, S, 2016)
"Our aim was to compare weekly rufloxacin with daily norfloxacin in the secondary prophylaxis of spontaneous bacterial peritonitis and to examine changes in antibiotic susceptibility in fecal Escherichia coli."9.10Daily norfloxacin is more effective than weekly rufloxacin in prevention of spontaneous bacterial peritonitis recurrence. ( Bauer, TM; Bory, F; Clemente, G; Follo, A; Navasa, M; Planas, R; Rodés, J; Vaquer, P; Vargas, V; Vila, J, 2002)
"Eighty cirrhotic patients who had recovered from an episode of spontaneous bacterial peritonitis were included in a multicenter, double-blind trial aimed at comparing long-term norfloxacin administration (400 mg/day; 40 patients) vs."9.06Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: results of a double-blind, placebo-controlled trial. ( Almela, M; Forné, M; Ginés, P; Llach, J; Marco, F; Miranda, ML; Planas, R; Rimola, A; Salmerón, JM; Vargas, V, 1990)
"For recipients who have received prophylactic norfloxacin, clinicians should be aware of the high risk of multidrug-resistant bacterial infections during the first month after liver transplant."8.31Impact of Prophylactic Norfloxacin in Multidrug Resistant Bacterial Infections in the Early Liver Posttransplant Period. ( Castells, L; Dopazo, C; Len, O; Lladó, L; Los-Arcos, I; Lung, M; Nuvials, X; Oriol, I; Pérez-Cameo, C; Sabé, N, 2023)
"In cirrhotic rats with ascites: (a) pentoxifylline as well as norfloxacin reduced intestinal bacterial overgrowth and bacterial translocation and prevented spontaneous bacterial peritonitis; (b) pentoxifylline, but not norfloxacin, reduced oxidative stress in cecal mucosal."7.78Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites. ( Acevedo, J; Brusasco, C; Corradi, F; Fernández, J; Fernández-Varo, G; Gines, P; Mosbah, IB; Navasa, M; Pelosi, P; Ramirez, MJ; Rocco, PR; Seva-Pereira, T; Silva, A; Vila, J, 2012)
"Although norfloxacin (N) is widely accepted as the drug of choice for spontaneous bacterial peritonitis (SBP) prophylaxis, there is data to suggest that trimethoprim-sulfamethoxazole (TS) may be similarly effective."7.74Norfloxacin and trimethoprim-sulfamethoxazole therapy have similar efficacy in prevention of spontaneous bacterial peritonitis. ( Angus, PW; Gow, PJ; Lontos, S; Vaughan, RB, 2008)
"The extensive use of invasive procedures and of long-term norfloxacin prophylaxis in the management of cirrhotic patients may have influenced the epidemiology of bacterial infections in cirrhosis."7.71Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. ( Arroyo, V; Colmenero, J; Fernández, J; Gómez, J; Navasa, M; Rodés, J; Vila, J, 2002)
"We carried out quantitative culturing of stools from 31 hospitalized alcoholic patients with cirrhosis and ascites, before treatment with 400 mg of norfloxacin per day, weekly for the first month, and then every 2 weeks thereafter for 15 to 229 days (median, 54 days)."7.69Rapid emergence of quinolone resistance in cirrhotic patients treated with norfloxacin to prevent spontaneous bacterial peritonitis. ( Campillo, B; Dupeyron, C; Fouet, P; Leluan, G; Mangeney, N; Sedrati, L, 1994)
"Pefloxacin was used as monotherapy in 15 cases of peritonitis occurring in patients undergoing continuous ambulatory peritoneal dialysis (CAPD)."7.67[Treatment of peritonitis in kidney failure patients under continuous ambulatory peritoneal dialysis by pefloxacine. Results and pharmacokinetics]. ( Benevent, D; Denis, F; Lagarde, C; Mounier, M, 1987)
" There was no difference among the studied groups regarding the incidence and severity of adverse events reported."6.82Efficacy and safety of alternating norfloxacin and rifaximin as primary prophylaxis for spontaneous bacterial peritonitis in cirrhotic ascites: a prospective randomized open-label comparative multicenter study. ( Abdelaziz, A; Abdelrashed, M; Assem, M; El-Azab, G; Elemam, S; Elsabaawy, M; Hamed, W; Khodeer, S, 2016)
"Norfloxacin was not superior to other antibiotics."6.66Efficacy of Norfloxacin Prophylaxis to Prevent Spontaneous Bacterial Peritonitis: A Systematic Review and Meta-Analysis. ( Fernandez, J; Ferstl, PG; Graf, C; Herrmann, E; Lange, CM; Mücke, MM; Mücke, VT; Schwarzkopf, KM; Trebicka, J; Zeuzem, S, 2020)
"The cumulative incidence of SBP recurrence was 28."5.51Spontaneous bacterial peritonitis recurrence in patients with cirrhosis receiving secondary prophylaxis with norfloxacin. ( Barcán, LA; Bermudez, C; Diaz, JM; Dirchwolf, M; Gadano, AC; Giunta, D; Gutierrez-Acevedo, MN; Marciano, S; Smud, A, 2019)
"The SBP recurrence rate was 42."5.37Recurrence of spontaneous bacterial peritonitis in cirrhotic patients non-prophylactically treated with norfloxacin: serum albumin as an easy but reliable predictive factor. ( Chen, WT; Chiu, CT; Ho, YP; Huang, CH; Lin, CY; Lin, TN; Sheen, IS, 2011)
"We performed a 5-year retrospective study to evaluate the effect of long-term administration of norfloxacin on the epidemiology of severe hospital-acquired infections in patients with advanced cirrhosis."5.30Epidemiology of severe hospital-acquired infections in patients with liver cirrhosis: effect of long-term administration of norfloxacin. ( Campillo, B; Dupeyron, C; Leluan, G; Mangeney, N; Richardet, JP, 1998)
"The 1-year recurrence rate of SBP can be as high as 30-70%."5.30An economic analysis of norfloxacin prophylaxis against spontaneous bacterial peritonitis. ( Ganiats, TG; McHutchison, JG; Younossi, ZM, 1997)
"Once weekly ciprofloxacin was as effective as daily norfloxacin for the prevention of SBP in cirrhotic patients with ascites."5.27Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial. ( Jang, JY; Jung, YK; Kim, BI; Kim, HS; Kim, YS; Lee, YR; Park, SY; Seo, YS; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2018)
"Two hundred and sixty two cirrhotic patients with ascites and a previous episode of SBP were assigned randomly to receive either 1200 mg rifaximin or 400 mg of norfloxacin daily for 6 months."5.22Randomized-controlled trial of rifaximin versus norfloxacin for secondary prophylaxis of spontaneous bacterial peritonitis. ( Abd-Elsalam, S; Abo Ali, L; Elfert, A; Ibrahim, S; Soliman, S, 2016)
"Norfloxacin administration reduced the 1-year probability of developing spontaneous bacterial peritonitis (7% vs 61%, P < ."5.12Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis. ( Arroyo, V; Fernández, J; Ginès, P; Monfort, D; Montoliu, S; Navasa, M; Pardo, A; Planas, R; Quintero, E; Soriano, G; Such, J; Vargas, V; Vila, C, 2007)
"Oral norfloxacin is the standard of therapy in the prophylaxis of bacterial infections in cirrhotic patients with gastrointestinal hemorrhage."5.12Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage. ( Arroyo, V; Durandez, R; Fernández, J; Gómez, C; Guarner, C; Navasa, M; Planas, R; Ruiz del Arbol, L; Serradilla, R, 2006)
"Our aim was to compare weekly rufloxacin with daily norfloxacin in the secondary prophylaxis of spontaneous bacterial peritonitis and to examine changes in antibiotic susceptibility in fecal Escherichia coli."5.10Daily norfloxacin is more effective than weekly rufloxacin in prevention of spontaneous bacterial peritonitis recurrence. ( Bauer, TM; Bory, F; Clemente, G; Follo, A; Navasa, M; Planas, R; Rodés, J; Vaquer, P; Vargas, V; Vila, J, 2002)
"Selective intestinal decontamination (SID) for 7 days with norfloxacin (NF) was performed in 15 patients with schistosomal hepatic fibrosis (SHF) and low-protein ascites."5.07Selective intestinal decontamination in patients with schistosomal hepatic fibrosis and low-protein ascites. ( Abou Seif Helmy, M; el Aggan, HA; el-Aggan, HA; Guirguis, TG, 1993)
"Eighty cirrhotic patients who had recovered from an episode of spontaneous bacterial peritonitis were included in a multicenter, double-blind trial aimed at comparing long-term norfloxacin administration (400 mg/day; 40 patients) vs."5.06Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: results of a double-blind, placebo-controlled trial. ( Almela, M; Forné, M; Ginés, P; Llach, J; Marco, F; Miranda, ML; Planas, R; Rimola, A; Salmerón, JM; Vargas, V, 1990)
" For primary prophylaxis, short-term antibiotic treatment (oral norfloxacin or ciprofloxacin) is indicated in cirrhotic patients (with or without ascites) admitted with gastrointestinal haemorrhage (variceal or non-variceal)."4.84[Bacterial infections in liver cirrhosis]. ( Farkas, A; Papp, M; Tornai, I; Udvardy, M, 2007)
"For recipients who have received prophylactic norfloxacin, clinicians should be aware of the high risk of multidrug-resistant bacterial infections during the first month after liver transplant."4.31Impact of Prophylactic Norfloxacin in Multidrug Resistant Bacterial Infections in the Early Liver Posttransplant Period. ( Castells, L; Dopazo, C; Len, O; Lladó, L; Los-Arcos, I; Lung, M; Nuvials, X; Oriol, I; Pérez-Cameo, C; Sabé, N, 2023)
"Consecutively admitted patients with cirrhosis and ascitic fluid (AF) with: spontaneous bacterial peritonitis (SBP), non-infected AF, and norfloxacin as secondary SBP prophylaxis (SID group)."3.83Selective intestinal decontamination with norfloxacin enhances a regulatory T cell-mediated inflammatory control mechanism in cirrhosis. ( Caparrós, E; Francés, R; Giménez, P; Gómez-Hurtado, I; González-Navajas, JM; Juanola, O; Moratalla, A; Piñero, P; Such, J; Zapater, P, 2016)
"In cirrhotic rats with ascites: (a) pentoxifylline as well as norfloxacin reduced intestinal bacterial overgrowth and bacterial translocation and prevented spontaneous bacterial peritonitis; (b) pentoxifylline, but not norfloxacin, reduced oxidative stress in cecal mucosal."3.78Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites. ( Acevedo, J; Brusasco, C; Corradi, F; Fernández, J; Fernández-Varo, G; Gines, P; Mosbah, IB; Navasa, M; Pelosi, P; Ramirez, MJ; Rocco, PR; Seva-Pereira, T; Silva, A; Vila, J, 2012)
" Thirty patients were taking norfloxacin or trimethoprim-sulfamethoxazole as prophylaxis against bacterial peritonitis and 11 were not."3.76Effects of antibiotics on expression and function of Toll-like receptors 2 and 4 on mononuclear cells in patients with advanced cirrhosis. ( Angus, PW; Gow, PJ; Markovska, V; Skinner, N; Testro, AG; Visvanathan, K; Wongseelashote, S, 2010)
" The bactDNA translocation was investigated in 226 patients with cirrhosis and noninfected ascites, 22 patients with spontaneous bacterial peritonitis, and 10 patients with ascites receiving continuous norfloxacin."3.74Bacterial DNA in patients with cirrhosis and noninfected ascites mimics the soluble immune response established in patients with spontaneous bacterial peritonitis. ( Bellot, P; Caño, R; Francés, R; González-Navajas, JM; Moreu, R; Muñoz, C; Pascual, S; Pérez-Mateo, M; Such, J; Zapater, P, 2008)
"Although norfloxacin (N) is widely accepted as the drug of choice for spontaneous bacterial peritonitis (SBP) prophylaxis, there is data to suggest that trimethoprim-sulfamethoxazole (TS) may be similarly effective."3.74Norfloxacin and trimethoprim-sulfamethoxazole therapy have similar efficacy in prevention of spontaneous bacterial peritonitis. ( Angus, PW; Gow, PJ; Lontos, S; Vaughan, RB, 2008)
"The objective of the study was to examine the characteristics of spontaneous bacterial peritonitis (SBP) caused by streptococci, in particular viridans group streptococci (VGS), and to investigate a potential association between the long-term administration of norfloxacin and high-level resistance to fluoroquinolones in these organisms."3.73Viridans group streptococci: an underestimated cause of spontaneous bacterial peritonitis in cirrhotic patients with ascites. ( Bert, F; Lambert-Zechovsky, N; Noussair, L; Valla, D, 2005)
" Norfloxacin 400 mg per day had been introduced three months earlier as secondary prophylaxis for spontaneous bacterial peritonitis."3.72[Spontaneous infection of ascitic fluid due to Salmonella typhimurium in a cirrhotic patient undergoing selective intestinal decontamination with norfloxacin]. ( Colin, R; Di Fiore, F; Goria, O; Hervé, S; Lecleire, S; Lerebours, E; Savoye, G, 2003)
"Norfloxacin decreases the incidence of spontaneous bacterial peritonitis in cirrhotics, but promotes the appearance of quinolone-resistant Escherichia coli."3.72Role of immunosuppression in the development of quinolone-resistant Escherichia coli spontaneous bacterial peritonitis and in the mortality of E. coli spontaneous bacterial peritonitis. ( Cereto, F; Del Valle, O; Esteban, R; Genescà, J; González, A; Guardia, J; Molina, I, 2003)
"Prophylaxis with norfloxacin has been shown to be effective in preventing spontaneous bacterial peritonitis (SBP) in liver cirrhosis."3.71Spontaneous bacterial peritonitis caused by quinolone-resistant Escherichia coli: could steroid therapy play a role? ( Cereto, F; del Valle Ortiz, O; Esteban, R; Genescà, J; González, A; Guardia, J; Moreno, G; Smithson, A, 2002)
"The extensive use of invasive procedures and of long-term norfloxacin prophylaxis in the management of cirrhotic patients may have influenced the epidemiology of bacterial infections in cirrhosis."3.71Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. ( Arroyo, V; Colmenero, J; Fernández, J; Gómez, J; Navasa, M; Rodés, J; Vila, J, 2002)
"We designed a prospective study to evaluate the incidence of Escherichia coli in stools at admission in patients with cirrhosis that had previously received norfloxacin as primary or secondary prophylaxis of spontaneous bacterial peritonitis (SBP) (group I, n = 28) vs those who did not (group II, n = 55)."3.70[Development of Escherichia coli strands resistant to quinolones in stools of patients with liver cirrhosis submitted to selective bowel decontamination]. ( Aparicio, JR; Arroyo, A; Gutiérrez, A; Pérez-Mateo, M; Plaza, J; Such, J, 1999)
"We carried out quantitative culturing of stools from 31 hospitalized alcoholic patients with cirrhosis and ascites, before treatment with 400 mg of norfloxacin per day, weekly for the first month, and then every 2 weeks thereafter for 15 to 229 days (median, 54 days)."3.69Rapid emergence of quinolone resistance in cirrhotic patients treated with norfloxacin to prevent spontaneous bacterial peritonitis. ( Campillo, B; Dupeyron, C; Fouet, P; Leluan, G; Mangeney, N; Sedrati, L, 1994)
"Spontaneous bacterial peritonitis in patients with and without prophylaxis with norfloxacin are not different in clinical features, response to treatment and prognosis."3.69Spontaneous bacterial peritonitis in patients with cirrhosis undergoing selective intestinal decontamination. A retrospective study of 229 spontaneous bacterial peritonitis episodes. ( Arroyo, V; Bataller, R; Cabré, E; Castells, A; Gassull, MA; Llovet, JM; Menacho, M; Moitinho, E; Navasa, M; Pardo, A; Planas, R; Rodés, J; Rodríguez-Iglesias, P, 1997)
"Pefloxacin was used as monotherapy in 15 cases of peritonitis occurring in patients undergoing continuous ambulatory peritoneal dialysis (CAPD)."3.67[Treatment of peritonitis in kidney failure patients under continuous ambulatory peritoneal dialysis by pefloxacine. Results and pharmacokinetics]. ( Benevent, D; Denis, F; Lagarde, C; Mounier, M, 1987)
" There was no difference among the studied groups regarding the incidence and severity of adverse events reported."2.82Efficacy and safety of alternating norfloxacin and rifaximin as primary prophylaxis for spontaneous bacterial peritonitis in cirrhotic ascites: a prospective randomized open-label comparative multicenter study. ( Abdelaziz, A; Abdelrashed, M; Assem, M; El-Azab, G; Elemam, S; Elsabaawy, M; Hamed, W; Khodeer, S, 2016)
"Norfloxacin was not superior to other antibiotics."2.66Efficacy of Norfloxacin Prophylaxis to Prevent Spontaneous Bacterial Peritonitis: A Systematic Review and Meta-Analysis. ( Fernandez, J; Ferstl, PG; Graf, C; Herrmann, E; Lange, CM; Mücke, MM; Mücke, VT; Schwarzkopf, KM; Trebicka, J; Zeuzem, S, 2020)
"The cumulative incidence of SBP recurrence was 28."1.51Spontaneous bacterial peritonitis recurrence in patients with cirrhosis receiving secondary prophylaxis with norfloxacin. ( Barcán, LA; Bermudez, C; Diaz, JM; Dirchwolf, M; Gadano, AC; Giunta, D; Gutierrez-Acevedo, MN; Marciano, S; Smud, A, 2019)
"The aac(6')-Ib-cr gene, in spite of producing low-level resistance by itself, plays a relevant role in acquisition of a clinical level of ciprofloxacin and norfloxacin resistance, when combined with three or four chromosomal mutations, both in vitro and in vivo."1.43Impact of AAC(6')-Ib-cr in combination with chromosomal-mediated mechanisms on clinical quinolone resistance in Escherichia coli. ( Díaz-De-Alba, P; Docobo-Perez, F; Machuca, J; Ortiz, M; Pascual, Á; Recacha, E; Rodríguez-Martínez, JM, 2016)
"The SBP recurrence rate was 42."1.37Recurrence of spontaneous bacterial peritonitis in cirrhotic patients non-prophylactically treated with norfloxacin: serum albumin as an easy but reliable predictive factor. ( Chen, WT; Chiu, CT; Ho, YP; Huang, CH; Lin, CY; Lin, TN; Sheen, IS, 2011)
"The 1-year recurrence rate of SBP can be as high as 30-70%."1.30An economic analysis of norfloxacin prophylaxis against spontaneous bacterial peritonitis. ( Ganiats, TG; McHutchison, JG; Younossi, ZM, 1997)
"We performed a 5-year retrospective study to evaluate the effect of long-term administration of norfloxacin on the epidemiology of severe hospital-acquired infections in patients with advanced cirrhosis."1.30Epidemiology of severe hospital-acquired infections in patients with liver cirrhosis: effect of long-term administration of norfloxacin. ( Campillo, B; Dupeyron, C; Leluan, G; Mangeney, N; Richardet, JP, 1998)
" The overall elimination half-life was 19."1.28Single-dose pefloxacin pharmacokinetics and metabolism in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). ( Dombros, N; Nikolaidis, P; Oreopoulos, DG; Paton, TW; Tourkantonis, A; Walker, SE, 1991)
" This risk may depend on the dosing schedule and may be reduced by combined therapy."1.27Resistance occurring after fluoroquinolone therapy of experimental Pseudomonas aeruginosa peritonitis. ( Auckenthaler, R; Michéa-Hamzehpour, M; Pechère, JC; Regamey, P, 1987)

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.15)18.7374
1990's20 (30.77)18.2507
2000's19 (29.23)29.6817
2010's19 (29.23)24.3611
2020's3 (4.62)2.80

Authors

AuthorsStudies
Marciano, S2
Gutierrez-Acevedo, MN2
Barbero, S1
Del C Notari, L1
Agozino, M1
Fernandez, JL1
Anders, MM1
Grigera, N1
Antinucci, F1
Orozco Ganem, OF1
Murga, MD1
Perez, D1
Palazzo, A1
Martinez Rejtman, L1
Duarte, IG1
Vorobioff, J1
Trevizan, V1
Bulaty, S1
Bessone, F1
Valverde, M1
Elizondo, M1
Bosia, JD1
Borzi, SM1
Stieben, TE1
Masola, A1
Ferretti, SE1
Arufe, D1
Demirdjian, E1
Raffa, MP1
Peralta, M1
Fainboim, HA1
Vazquez, CE1
Ruiz, P1
Martínez, JE1
Heffner, LA1
Odzak, A1
Dirchwolf, M2
Smud, A2
Mendizabal, M1
Bellizzi, C1
Martinez, A1
Tomatis, J1
Bruno, A1
Ramos, A1
Pages, J1
Tevez, S1
Gadano, AC2
Giunta, DH1
Pérez-Cameo, C1
Oriol, I1
Lung, M1
Lladó, L1
Dopazo, C1
Nuvials, X1
Los-Arcos, I1
Sabé, N1
Castells, L1
Len, O1
Mücke, MM1
Mücke, VT1
Graf, C1
Schwarzkopf, KM1
Ferstl, PG1
Fernandez, J5
Zeuzem, S1
Trebicka, J1
Lange, CM1
Herrmann, E1
Yim, HJ1
Suh, SJ1
Jung, YK1
Yim, SY1
Seo, YS1
Lee, YR1
Park, SY1
Jang, JY1
Kim, YS1
Kim, HS1
Kim, BI1
Um, SH1
Menshawy, A1
Mattar, O1
Barssoum, K1
AboEl-Naga, AM1
Salim, HM1
Mohamed, AMF1
Elgebaly, A1
Abd-Elsalam, S2
Diaz, JM1
Bermudez, C1
Barcán, LA1
Giunta, D1
Facciorusso, A1
Papagiouvanni, I1
Cela, M1
Buccino, VR1
Sacco, R1
Wang, W2
Yang, J1
Liu, C1
Song, P1
Xu, H1
Xia, X1
Saffouri, GB1
Wittich, CM1
Lontos, S2
Shelton, E1
Angus, PW3
Vaughan, R1
Roberts, SK1
Gordon, A1
Gow, PJ3
Mostafa, T1
Badra, G1
Abdallah, M1
Salerno, F1
La Mura, V1
Assem, M1
Elsabaawy, M1
Abdelrashed, M1
Elemam, S1
Khodeer, S1
Hamed, W1
Abdelaziz, A1
El-Azab, G1
Juanola, O1
Gómez-Hurtado, I2
Zapater, P5
Moratalla, A1
Caparrós, E1
Piñero, P1
González-Navajas, JM3
Giménez, P1
Such, J8
Francés, R5
Machuca, J1
Ortiz, M1
Recacha, E1
Díaz-De-Alba, P1
Docobo-Perez, F1
Rodríguez-Martínez, JM1
Pascual, Á1
Elfert, A1
Abo Ali, L1
Soliman, S1
Ibrahim, S1
Bert, F2
Leflon-Guibout, V1
Le Grand, J1
Bourdon, N1
Nicolas-Chanoine, MH1
Caño, R3
Llanos, L1
Ruiz-Alcaraz, AJ1
Pascual, S4
Barquero, C1
Moreu, R2
Bellot, P3
Horga, JF1
Muñoz, C3
Pérez, J1
García-Peñarrubia, P1
Pérez-Mateo, M5
Testro, AG1
Wongseelashote, S1
Skinner, N1
Markovska, V1
Visvanathan, K1
Huang, CH1
Lin, CY1
Sheen, IS1
Chen, WT1
Lin, TN1
Ho, YP1
Chiu, CT1
Corradi, F1
Brusasco, C1
Vila, J3
Ramirez, MJ1
Seva-Pereira, T1
Fernández-Varo, G1
Mosbah, IB1
Acevedo, J1
Silva, A1
Rocco, PR1
Pelosi, P1
Gines, P3
Navasa, M6
Pande, C1
Kumar, A1
Sarin, SK2
Karakan, T1
Tahtaci, M1
Alagozlu, H1
Cereto, F2
Molina, I1
González, A2
Del Valle, O1
Esteban, R2
Guardia, J2
Genescà, J2
Lecleire, S1
Di Fiore, F1
Hervé, S1
Goria, O1
Savoye, G1
Colin, R1
Lerebours, E1
Sandhu, BS1
Gupta, R1
Sharma, J1
Singh, J1
Murthy, NS1
Noussair, L1
Lambert-Zechovsky, N1
Valla, D1
Itha, S1
Sharma, A1
Bhatt, G1
Ruiz del Arbol, L1
Gómez, C1
Durandez, R1
Serradilla, R1
Guarner, C4
Planas, R5
Arroyo, V4
Papp, M1
Farkas, A1
Udvardy, M1
Tornai, I1
Márquez, D1
Santana, F1
Vaughan, RB1
Montoliu, S1
Monfort, D1
Soriano, G3
Vila, C1
Pardo, A2
Quintero, E1
Vargas, V3
Runyon, BA2
Menon, S1
Velayos Jiménez, B1
Fernández Salazar, L1
Aller Fuente, R1
del Olmo Martínez, L1
de la Calle Valverde, F1
Arranz Santos, T1
González Hernández, JM1
Schölmerich, J2
Gerbes, AL1
Andus, T1
Leser, HG1
Borzio, M1
Young, S1
Squier, SU1
Runyon, MA1
Castellote, J1
Xiol, J1
Rota Roca, R1
Fernandez Esparrach, G1
Dupeyron, C2
Mangeney, N2
Sedrati, L1
Campillo, B2
Fouet, P1
Leluan, G2
Doershuk, CF1
Stern, RC1
el Aggan, HA1
el-Aggan, HA1
Abou Seif Helmy, M1
Guirguis, TG1
Novella, M1
Solà, R1
Andreu, M1
Gana, J1
Ortiz, J1
Coll, S1
Sàbat, M1
Vila, MC1
Vilardell, F2
Llovet, JM1
Rodríguez-Iglesias, P1
Moitinho, E1
Bataller, R1
Menacho, M1
Castells, A1
Cabré, E1
Gassull, MA1
Rodés, J3
Younossi, ZM1
McHutchison, JG1
Ganiats, TG1
Barrio, J1
Castiella, A1
López, P1
Indart, A1
Arenas, JI1
Glück, T1
Richardet, JP1
Romero-Gómez, M1
Suárez García, E1
Fernández, MC1
Jeffries, MA1
Stern, MA1
Gunaratnam, NT1
Fontana, RJ1
Aparicio, JR1
Gutiérrez, A1
Plaza, J1
Arroyo, A1
Smithson, A1
Moreno, G1
del Valle Ortiz, O1
Gómez, J1
Colmenero, J1
Bauer, TM1
Follo, A1
Clemente, G1
Bory, F1
Vaquer, P1
Schubert, ML1
Sanyal, AJ1
Wong, ES1
Teixidó, M1
Barrios, J1
Enríquez, J1
Nikolaidis, P1
Walker, SE1
Dombros, N1
Tourkantonis, A1
Paton, TW1
Oreopoulos, DG1
Rimola, A1
Marco, F1
Almela, M1
Forné, M1
Miranda, ML1
Llach, J1
Salmerón, JM1
Hoefs, JC1
Nord, CE1
Edlund, C1
Lahnborg, G1
Pechère, JC2
Marchou, B1
Michéa-Hamzehpour, M2
Auckenthaler, R2
Regamey, P1
Denis, F1
Mounier, M1
Lagarde, C1
Benevent, D1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Rifaximin Versus Norfloxacin in the Primary Prophylaxis of Spontaneous Bacterial Peritonitis[NCT04159870]Phase 3322 participants (Anticipated)Interventional2019-11-05Active, not recruiting
The Efficacy and Safety of Rifaximin In The Treatment of HBV Associated Acute-on-Chronic Liver Failure Patients With Mild to Moderate Hepatic Encephalopathy[NCT05786859]Early Phase 1124 participants (Anticipated)Interventional2023-03-09Recruiting
Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis in Patients With Acute Variceal Bleeding[NCT00838864]Phase 479 participants (Actual)Interventional2009-03-31Completed
Asymptomatic Spontaneous Bacterial Peritonitis in Patients With Decompensated Liver Cirrhosis in Upper Egypt : A Prospective Hospital Based Study[NCT03163745]70 participants (Actual)Observational2019-03-11Completed
Comparison of Daily Norfloxacin Versus Weekly Ciprofloxacin for the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients[NCT01542801]Phase 4124 participants (Actual)Interventional2011-08-31Completed
Patterns of Antibiotic Resistant Bacterial Infections in Liver Intensive Care Unit[NCT03855709]200 participants (Anticipated)Observational2019-05-31Not yet recruiting
Rifaximin Prophylaxis Against Recurrence of Spontaneous Bacterial Peritonitis and Occurrence of Hepatorenal Syndrome in Decompensated Cirrhotic Egyptian Patients[NCT05621005]Phase 2104 participants (Actual)Interventional2019-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for norfloxacin and Peritonitis

ArticleYear
Efficacy of Norfloxacin Prophylaxis to Prevent Spontaneous Bacterial Peritonitis: A Systematic Review and Meta-Analysis.
    Clinical and translational gastroenterology, 2020, Volume: 11, Issue:8

    Topics: Antibiotic Prophylaxis; Bacterial Infections; Drug Resistance, Multiple, Bacterial; Humans; Incidenc

2020
Safety and Efficacy of Rifaximin in Prophylaxis of Spontaneous Bacterial Peritonitis: A Systematic Review and Meta-analysis.
    Current drug targets, 2019, Volume: 20, Issue:4

    Topics: Antibiotic Prophylaxis; Bacterial Infections; Drug Therapy, Combination; Female; Humans; Norfloxacin

2019
Comparative efficacy of long-term antibiotic treatments in the primary prophylaxis of spontaneous bacterial peritonitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:8

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Humans; Incidence; Norfloxacin;

2019
Norfloxacin, ciprofloxacin, trimethoprim-sulfamethoxazole, and rifaximin for the prevention of spontaneous bacterial peritonitis: a network meta-analysis.
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:8

    Topics: Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Humans; Network Meta-Analysis; Norfloxac

2019
[Emergence of vancomycin-dependent enterococci following glycopeptide therapy: case report and review].
    Pathologie-biologie, 2009, Volume: 57, Issue:1

    Topics: Bacterial Proteins; Bacteriuria; Carbon-Oxygen Ligases; Cecal Diseases; Ceftriaxone; Citrobacter fre

2009
[Bacterial infections in liver cirrhosis].
    Orvosi hetilap, 2007, Mar-04, Volume: 148, Issue:9

    Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ascites;

2007
[Spontaneous bacterial peritonitis in liver cirrhosis with ascites].
    Deutsche medizinische Wochenschrift (1946), 1995, Mar-31, Volume: 120, Issue:13

    Topics: Anti-Bacterial Agents; Ascites; Bacteria; Bacterial Infections; Blood; Endoscopy; Humans; Leukocyte

1995
[Spontaneous bacterial peritonitis].
    Der Internist, 1998, Volume: 39, Issue:3

    Topics: Animals; Ascites; Bacterial Infections; Bacterial Translocation; Cefotaxime; Diagnosis, Differential

1998

Trials

16 trials available for norfloxacin and Peritonitis

ArticleYear
Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial.
    The American journal of gastroenterology, 2018, Volume: 113, Issue:8

    Topics: Adult; Aged; Anti-Bacterial Agents; Ascites; Bacterial Infections; Ciprofloxacin; Disease-Free Survi

2018
A randomized controlled study of trimethoprim-sulfamethoxazole versus norfloxacin for the prevention of infection in cirrhotic patients.
    Journal of digestive diseases, 2014, Volume: 15, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Bacterial I

2014
The efficacy and the immunomodulatory effect of rifaximin in prophylaxis of spontaneous bacterial peritonitis in cirrhotic Egyptian patients.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2015, Volume: 26, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Ascites; Bacterial Infections; Female; Humans; Interleukin-10; Interle

2015
Efficacy and safety of alternating norfloxacin and rifaximin as primary prophylaxis for spontaneous bacterial peritonitis in cirrhotic ascites: a prospective randomized open-label comparative multicenter study.
    Hepatology international, 2016, Volume: 10, Issue:2

    Topics: Adult; Aged; Antibiotic Prophylaxis; Bacterial Infections; Drug Administration Schedule; Female; Hum

2016
Randomized-controlled trial of rifaximin versus norfloxacin for secondary prophylaxis of spontaneous bacterial peritonitis.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ascites; Bacterial Infections; Cause of Death; Egypt;

2016
Norfloxacin modulates the inflammatory response and directly affects neutrophils in patients with decompensated cirrhosis.
    Gastroenterology, 2009, Volume: 137, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Cohort Studies; Cross-Over Studies; Cytokines; Fe

2009
Addition of probiotics to norfloxacin does not improve efficacy in the prevention of spontaneous bacterial peritonitis: a double-blind placebo-controlled randomized-controlled trial.
    European journal of gastroenterology & hepatology, 2012, Volume: 24, Issue:7

    Topics: Adolescent; Adult; Aged; Antibiotic Prophylaxis; Bacterial Infections; Combined Modality Therapy; Do

2012
Norfloxacin and cisapride combination decreases the incidence of spontaneous bacterial peritonitis in cirrhotic ascites.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:4

    Topics: Adult; Analysis of Variance; Anti-Infective Agents; Ascites; Chi-Square Distribution; Cisapride; Dru

2005
Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage.
    Gastroenterology, 2006, Volume: 131, Issue:4

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Ba

2006
Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis.
    Gastroenterology, 2007, Volume: 133, Issue:3

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Double-Blind Method; Female; Hepatorenal Syndro

2007
Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis.
    Gastroenterology, 2007, Volume: 133, Issue:3

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Double-Blind Method; Female; Hepatorenal Syndro

2007
Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis.
    Gastroenterology, 2007, Volume: 133, Issue:3

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Double-Blind Method; Female; Hepatorenal Syndro

2007
Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis.
    Gastroenterology, 2007, Volume: 133, Issue:3

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Double-Blind Method; Female; Hepatorenal Syndro

2007
Selective intestinal decontamination in patients with schistosomal hepatic fibrosis and low-protein ascites.
    Journal of the Egyptian Society of Parasitology, 1993, Volume: 23, Issue:3

    Topics: Adult; Animals; Ascites; Ascitic Fluid; Humans; Intestines; Liver Cirrhosis; Norfloxacin; Peritoniti

1993
Continuous versus inpatient prophylaxis of the first episode of spontaneous bacterial peritonitis with norfloxacin.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:3

    Topics: Anti-Infective Agents; Ascites; Bacterial Infections; Drug Administration Schedule; Drug Resistance,

1997
Daily norfloxacin is more effective than weekly rufloxacin in prevention of spontaneous bacterial peritonitis recurrence.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:6

    Topics: Aged; Anti-Infective Agents; Female; Fluoroquinolones; Humans; Liver Cirrhosis; Male; Middle Aged; N

2002
Antibiotic prophylaxis for prevention of spontaneous bacterial peritonitis?
    Gastroenterology, 1991, Volume: 101, Issue:2

    Topics: Bacterial Infections; Cost-Benefit Analysis; Humans; Liver Cirrhosis; Norfloxacin; Peritonitis

1991
Selective intestinal decontamination prevents spontaneous bacterial peritonitis.
    Gastroenterology, 1991, Volume: 100, Issue:2

    Topics: Aged; Ascitic Fluid; Bacterial Infections; Female; Hospitalization; Humans; Intestines; Liver Cirrho

1991
Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: results of a double-blind, placebo-controlled trial.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:4 Pt 1

    Topics: Bacterial Infections; Double-Blind Method; Drug Administration Schedule; Feces; Female; Humans; Live

1990

Other Studies

41 other studies available for norfloxacin and Peritonitis

ArticleYear
Norfloxacin prophylaxis effect on multidrug resistance in patients with cirrhosis and bacterial infections.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2023, Volume: 42, Issue:4

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Cross-Sectional Studies; Drug R

2023
Impact of Prophylactic Norfloxacin in Multidrug Resistant Bacterial Infections in the Early Liver Posttransplant Period.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2023, Volume: 21, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; End Stage Liver Disease; Humans; Liver Cirrhosis

2023
Spontaneous bacterial peritonitis recurrence in patients with cirrhosis receiving secondary prophylaxis with norfloxacin.
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Female; Humans; Li

2019
83-year-old man with abdominal swelling and lower extremity edema.
    Mayo Clinic proceedings, 2013, Volume: 88, Issue:10

    Topics: Abdominal Cavity; Aged, 80 and over; Anti-Infective Agents; Ascites; Cefotaxime; Diagnosis, Differen

2013
Treatment of Spontaneous Bacterial Peritonitis.
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:4

    Topics: Age Factors; Albumins; Anti-Bacterial Agents; Antibiotic Prophylaxis; Ascites; Bilirubin; Drug Resis

2015
Selective intestinal decontamination with norfloxacin enhances a regulatory T cell-mediated inflammatory control mechanism in cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2016, Volume: 36, Issue:12

    Topics: Adoptive Transfer; Aged; Animals; Anti-Bacterial Agents; B7-1 Antigen; B7-2 Antigen; Bacterial Infec

2016
Impact of AAC(6')-Ib-cr in combination with chromosomal-mediated mechanisms on clinical quinolone resistance in Escherichia coli.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Chromosomes, Bacterial; Ciprofloxacin; Disease Models, Animal; Esche

2016
Effects of antibiotics on expression and function of Toll-like receptors 2 and 4 on mononuclear cells in patients with advanced cirrhosis.
    Journal of hepatology, 2010, Volume: 52, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Case-Control Studies; Female; Gram-Negative Bacterial Infections

2010
Recurrence of spontaneous bacterial peritonitis in cirrhotic patients non-prophylactically treated with norfloxacin: serum albumin as an easy but reliable predictive factor.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Liver Cirrhosis; Logistic Models; Male;

2011
Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Cells, Cultured; Cyclooxygenase 2; DNA, Bacterial; Down-Regulation; Fe

2011
Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Ascites; Ascitic Fluid; Bacterial Translocatio

2012
Probiotics: should we be more definitive in terminology?
    European journal of gastroenterology & hepatology, 2012, Volume: 24, Issue:9

    Topics: Bacterial Infections; Female; Humans; Male; Norfloxacin; Peritonitis; Probiotics

2012
Role of immunosuppression in the development of quinolone-resistant Escherichia coli spontaneous bacterial peritonitis and in the mortality of E. coli spontaneous bacterial peritonitis.
    Alimentary pharmacology & therapeutics, 2003, Mar-01, Volume: 17, Issue:5

    Topics: Anti-Infective Agents; Ascitic Fluid; Drug Resistance, Bacterial; Escherichia coli Infections; Human

2003
[Spontaneous infection of ascitic fluid due to Salmonella typhimurium in a cirrhotic patient undergoing selective intestinal decontamination with norfloxacin].
    Presse medicale (Paris, France : 1983), 2003, Mar-29, Volume: 32, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Ascitic Fluid; Blood; Cefotaxi

2003
Viridans group streptococci: an underestimated cause of spontaneous bacterial peritonitis in cirrhotic patients with ascites.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:9

    Topics: Anti-Bacterial Agents; Ascitic Fluid; Drug Administration Schedule; Drug Resistance, Bacterial; Fema

2005
Norfloxacin and cisapride combination decreases the incidence of spontaneous bacterial peritonitis in cirrhotic ascites.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:10

    Topics: Anti-Infective Agents; Ascites; Bacterial Infections; Cisapride; Drug Therapy, Combination; Gastroin

2006
Bacterial DNA induces the complement system activation in serum and ascitic fluid from patients with advanced cirrhosis.
    Journal of clinical immunology, 2007, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ascites; Ascitic Fluid; Bacterial Infections;

2007
Norfloxacin and trimethoprim-sulfamethoxazole therapy have similar efficacy in prevention of spontaneous bacterial peritonitis.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Female; Humans; Male; Mid

2008
A pill a day can improve survival in patients with advanced cirrhosis.
    Gastroenterology, 2007, Volume: 133, Issue:3

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Hepatorenal Syndrome; Humans; Liver Cirrhosis; Norflo

2007
Primary prophylaxis of SBP.
    Gastroenterology, 2008, Volume: 134, Issue:2

    Topics: Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Bacterial; Enteritis; Enterocoliti

2008
Bacterial DNA in patients with cirrhosis and noninfected ascites mimics the soluble immune response established in patients with spontaneous bacterial peritonitis.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Ascites; Bacterial Infections; DNA, Bacterial; Female; Humans; I

2008
[Spontaneous bacterial peritonitis due to Gemella morbillorum in a patient under chronic treatment with norfloxacin].
    Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Ascites; Humans; Liver Cirrhosis, Alcoholic; Mal

2008
Effect of selective bowel decontamination with norfloxacin on spontaneous bacterial peritonitis, translocation, and survival in an animal model of cirrhosis.
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:6

    Topics: Administration, Oral; Animals; Carbon Tetrachloride Poisoning; Enterobacteriaceae; Enterobacteriacea

1995
Spontaneous bacterial peritonitis and empyema by Escherichia coli resistant to norfloxacine in a patient on selective intestinal decontamination with norfloxacine.
    Journal of hepatology, 1994, Volume: 20, Issue:3

    Topics: Drug Resistance, Microbial; Empyema; Escherichia coli Infections; Female; Humans; Incidence; Intesti

1994
Rapid emergence of quinolone resistance in cirrhotic patients treated with norfloxacin to prevent spontaneous bacterial peritonitis.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Ascites; Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Feces; Human

1994
Spontaneous bacterial peritonitis in cystic fibrosis.
    Gut, 1994, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Bacterial Infections; Cystic Fibrosis; Female; Humans; Liver Cirrhosis; Male; Nor

1994
Spontaneous bacterial peritonitis in patients with cirrhosis undergoing selective intestinal decontamination. A retrospective study of 229 spontaneous bacterial peritonitis episodes.
    Journal of hepatology, 1997, Volume: 26, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Translocation; Female; Humans; Inci

1997
An economic analysis of norfloxacin prophylaxis against spontaneous bacterial peritonitis.
    Journal of hepatology, 1997, Volume: 27, Issue:2

    Topics: Anti-Infective Agents; Bacterial Infections; Cost Savings; Health Care Costs; Humans; Life Expectanc

1997
[Spontaneous bacterial peritonitis caused by Streptococcus milleri in a cirrhotic patient with selective intestinal decontamination].
    Gastroenterologia y hepatologia, 1998, Volume: 21, Issue:1

    Topics: Aged; Anti-Infective Agents; Humans; Intestines; Liver Cirrhosis, Alcoholic; Male; Norfloxacin; Peri

1998
Epidemiology of severe hospital-acquired infections in patients with liver cirrhosis: effect of long-term administration of norfloxacin.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:5

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Ascitic Fluid; Bacteremia; Cross Infection; Dru

1998
Norfloxacin-induced acute cholestatic hepatitis in a patient with alcoholic liver cirrhosis.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:8

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Chemical and Drug Induced Liver Injury; Cholestasis,

1999
Unsuspected infection is infrequent in asymptomatic outpatients with refractory ascites undergoing therapeutic paracentesis.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:10

    Topics: Adult; Aged; Ambulatory Care; Anti-Infective Agents; Antibiotic Prophylaxis; Ascites; Ascitic Fluid;

1999
[Development of Escherichia coli strands resistant to quinolones in stools of patients with liver cirrhosis submitted to selective bowel decontamination].
    Medicina clinica, 1999, Sep-11, Volume: 113, Issue:7

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Escherichia coli; Escherichia coli Infections;

1999
Spontaneous bacterial peritonitis caused by quinolone-resistant Escherichia coli: could steroid therapy play a role?
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:1

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Drug Resistance, Bacterial; Escherichia coli; E

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Single-dose pefloxacin pharmacokinetics and metabolism in patients undergoing continuous ambulatory peritoneal dialysis (CAPD).
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1991, Volume: 11, Issue:1

    Topics: Administration, Oral; Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Infusions,

1991
Spontaneous bacterial peritonitis: prevention and therapy.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:4 Pt 1

    Topics: Anti-Bacterial Agents; Bacterial Infections; Humans; Liver Cirrhosis; Norfloxacin; Peritonitis

1990
The efficacy of pefloxacin in comparison to gentamicin in the treatment of experimentally induced peritonitis in rats.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 17 Suppl B

    Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Bacteroides fragilis; Clo

1986
Emergence of resistance after therapy with antibiotics used alone or combined in a murine model.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 17 Suppl A

    Topics: Amikacin; Animals; Bacteria; Bacterial Infections; Ceftriaxone; Drug Resistance, Microbial; Drug The

1986
Resistance occurring after fluoroquinolone therapy of experimental Pseudomonas aeruginosa peritonitis.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:11

    Topics: Animals; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Mice; Mice, I

1987
[Treatment of peritonitis in kidney failure patients under continuous ambulatory peritoneal dialysis by pefloxacine. Results and pharmacokinetics].
    Pathologie-biologie, 1987, Volume: 35, Issue:5

    Topics: Adult; Aged; Anti-Infective Agents; Drug Tolerance; Humans; Kidney Failure, Chronic; Middle Aged; No

1987