Page last updated: 2024-11-01

norfloxacin and Osteomyelitis

norfloxacin has been researched along with Osteomyelitis in 5 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Osteomyelitis: INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.

Research Excerpts

ExcerptRelevanceReference
"Norfloxacin (NFLX), a new quinolone antibiotic agent, was evaluated for its efficacy in experimental osteomyelitis in rabbits."7.68[Therapeutic efficacy of norfloxacin for experimental osteomyelitis in rabbits]. ( Aijima, H; Kaetsu, M; Okada, J, 1992)
"Pefloxacin was evaluated in the treatment of bone infections."5.27The diffusion of pefloxacin into bone and the treatment of osteomyelitis. ( Bernard, E; Dellamonica, P; Etesse, H; Garraffo, R, 1986)
"Norfloxacin (NFLX), a new quinolone antibiotic agent, was evaluated for its efficacy in experimental osteomyelitis in rabbits."3.68[Therapeutic efficacy of norfloxacin for experimental osteomyelitis in rabbits]. ( Aijima, H; Kaetsu, M; Okada, J, 1992)
"Following a summary of the main bacteriological and pharmacokinetic properties of this new quinolone derivative, the author reviews the results obtained with pefloxacine in the treatment of urinary tract infection, gonococcal urethritis, and bronchopulmonary, surgical, gynaecological, bone, soft tissue, neuromeningeal and ENT infections."3.67[Pefloxacin: evaluation and clinical prospects]. ( Modaï, J, 1986)
"Pefloxacin was evaluated in the treatment of bone infections."1.27The diffusion of pefloxacin into bone and the treatment of osteomyelitis. ( Bernard, E; Dellamonica, P; Etesse, H; Garraffo, R, 1986)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okada, J1
Kaetsu, M1
Aijima, H1
Yu, D1
Tsai, CL1
Wong, J1
Fox, JL1
Neu, HC1
Dellamonica, P1
Bernard, E1
Etesse, H1
Garraffo, R1
Modaï, J1

Other Studies

5 other studies available for norfloxacin and Osteomyelitis

ArticleYear
[Therapeutic efficacy of norfloxacin for experimental osteomyelitis in rabbits].
    The Japanese journal of antibiotics, 1992, Volume: 45, Issue:5

    Topics: Animals; Drug Evaluation; Drug Resistance, Microbial; Male; Norfloxacin; Osteomyelitis; Rabbits; Sta

1992
Hydroxyapatite cement based drug delivery systems: drug release in vitro.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1991, Volume: 90, Issue:10

    Topics: Bone Cements; Cephalexin; Delayed-Action Preparations; Fractures, Open; Hydroxyapatites; In Vitro Te

1991
Clinical use of the quinolones.
    Lancet (London, England), 1987, Dec-05, Volume: 2, Issue:8571

    Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Enoxacin; Gastrointestinal Diseases; Humans; Naphthy

1987
The diffusion of pefloxacin into bone and the treatment of osteomyelitis.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 17 Suppl B

    Topics: Adult; Aged; Anti-Bacterial Agents; Biopsy; Bone and Bones; Calcium; Chromatography, High Pressure L

1986
[Pefloxacin: evaluation and clinical prospects].
    La Revue de medecine interne, 1986, Volume: 7, Issue:2

    Topics: Bacterial Infections; Evaluation Studies as Topic; Female; Humans; Lung Diseases; Male; Meningitis;

1986