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norfloxacin and Mycoses

norfloxacin has been researched along with Mycoses in 11 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Mycoses: Diseases caused by FUNGI.

Research Excerpts

ExcerptRelevanceReference
"The effect of a combination regimen using norfloxacin (NFLX) and amphotericin B (AMPH-B) for prevention of infections in patients with acute leukemia being treated by remission-induction chemotherapy in a randomized, controlled trial was studied."9.07Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B. ( Dan, K; Nomura, T; Yamada, T, 1993)
"The efficacy and safety of norfloxacin were compared with those of placebo, vancomycin-polymyxin, and trimethoprim-sulfamethoxazole (TMP/SMX) for prophylaxis of bacterial infections in granulocytopenic patients."9.06Norfloxacin for prevention of bacterial infections in granulocytopenic patients. ( Bartlett, J; Champlin, RE; Deresinski, S; Finley, RS; Ho, WG; Joshi, JH; Karp, J; Levitt, L; Talbot, G; Winston, DJ, 1987)
"We evaluated the effect of norfloxacin, 400 mg given orally every 12 hours, on the prevention of bacterial infections in 68 adult patients who had acute leukemia throughout prolonged courses of granulocytopenia (median, 32 days)."9.06Oral norfloxacin for prevention of gram-negative bacterial infections in patients with acute leukemia and granulocytopenia. A randomized, double-blind, placebo-controlled trial. ( Bamberger, BJ; Bartlett, JG; Burke, PJ; Hendricksen, C; Karp, JE; Laughon, B; Merz, WG; Redden, T; Saral, R, 1987)
"The effect of a combination regimen using norfloxacin (NFLX) and amphotericin B (AMPH-B) for prevention of infections in patients with acute leukemia being treated by remission-induction chemotherapy in a randomized, controlled trial was studied."5.07Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B. ( Dan, K; Nomura, T; Yamada, T, 1993)
"The efficacy and safety of norfloxacin were compared with those of placebo, vancomycin-polymyxin, and trimethoprim-sulfamethoxazole (TMP/SMX) for prophylaxis of bacterial infections in granulocytopenic patients."5.06Norfloxacin for prevention of bacterial infections in granulocytopenic patients. ( Bartlett, J; Champlin, RE; Deresinski, S; Finley, RS; Ho, WG; Joshi, JH; Karp, J; Levitt, L; Talbot, G; Winston, DJ, 1987)
"We evaluated the effect of norfloxacin, 400 mg given orally every 12 hours, on the prevention of bacterial infections in 68 adult patients who had acute leukemia throughout prolonged courses of granulocytopenia (median, 32 days)."5.06Oral norfloxacin for prevention of gram-negative bacterial infections in patients with acute leukemia and granulocytopenia. A randomized, double-blind, placebo-controlled trial. ( Bamberger, BJ; Bartlett, JG; Burke, PJ; Hendricksen, C; Karp, JE; Laughon, B; Merz, WG; Redden, T; Saral, R, 1987)
"Selective antimicrobial decontamination with norfloxacin was compared with vancomycin/polymyxin for prophylaxis of bacterial infections in granulocytopenic patients."3.67Norfloxacin versus vancomycin/polymyxin for prevention of infections in granulocytopenic patients. ( Champlin, RE; Gale, RP; Ho, WG; Nakao, SL; Winston, DJ, 1986)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Makawana, JA1
Mungra, DC1
Patel, MP1
Patel, RG1
Shelke, SN1
Mhaske, GR1
Bonifácio, VD1
Gawande, MB1
Yin, BT1
Yan, CY1
Peng, XM2
Zhang, SL1
Rasheed, S1
Geng, RX2
Zhou, CH2
Karad, SC1
Purohit, VB1
Thakor, P1
Thakkar, VR1
Raval, DK1
Jeyakkumar, P1
Liu, HB1
Gopala, L1
Cheng, Y1
Yamada, T2
Dan, K2
Nomura, T2
Zwaveling, JH1
Maring, JK1
Klompmaker, IJ1
Haagsma, EB1
Bottema, JT1
Laseur, M1
Winter, HL1
van Enckevort, PJ1
TenVergert, EM1
Metselaar, HJ1
Bruining, HA1
Slooff, MJ1
Ogata, K1
Tanabe, Y1
Iwakiri, K1
Ito, T1
Winston, DJ2
Ho, WG2
Nakao, SL1
Gale, RP1
Champlin, RE2
Karp, J1
Bartlett, J1
Finley, RS1
Joshi, JH1
Talbot, G1
Levitt, L1
Deresinski, S1
Karp, JE1
Merz, WG1
Hendricksen, C1
Laughon, B1
Redden, T1
Bamberger, BJ1
Bartlett, JG1
Saral, R1
Burke, PJ1

Trials

4 trials available for norfloxacin and Mycoses

ArticleYear
Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B.
    Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:9

    Topics: Administration, Oral; Adult; Amphotericin B; Antineoplastic Agents; Bacterial Infections; Drug Combi

1993
Selective decontamination of the digestive tract to prevent postoperative infection: a randomized placebo-controlled trial in liver transplant patients.
    Critical care medicine, 2002, Volume: 30, Issue:6

    Topics: Adult; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacterial Infections; Decontaminati

2002
Norfloxacin for prevention of bacterial infections in granulocytopenic patients.
    The American journal of medicine, 1987, Jun-26, Volume: 82, Issue:6B

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Drug Combinations; Drug Therapy, Com

1987
Oral norfloxacin for prevention of gram-negative bacterial infections in patients with acute leukemia and granulocytopenia. A randomized, double-blind, placebo-controlled trial.
    Annals of internal medicine, 1987, Volume: 106, Issue:1

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Agents

1987

Other Studies

7 other studies available for norfloxacin and Mycoses

ArticleYear
Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus.
    Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Candida albicans; Fungi; Gram-Negative Bacte

2011
Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives.
    Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17

    Topics: Anti-Infective Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; Green Chemistry

2012
Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin.
    European journal of medicinal chemistry, 2014, Volume: 71

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Cattle; Chalcones; DNA; Fungi; Human

2014
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Anti-Infective Agents; Antimalarials; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi;

2016
Novel benzimidazolyl tetrahydroprotoberberines: Design, synthesis, antimicrobial evaluation and multi-targeting exploration.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Benzimidazoles; Berberine Alkaloids;

2017
Two cases of disseminated Trichosporon beigelii infection treated with combination antifungal therapy.
    Cancer, 1990, Jun-15, Volume: 65, Issue:12

    Topics: Adult; Amphotericin B; Drug Combinations; Flucytosine; Humans; Leukemia, Myeloid, Acute; Lymphoma, N

1990
Norfloxacin versus vancomycin/polymyxin for prevention of infections in granulocytopenic patients.
    The American journal of medicine, 1986, Volume: 80, Issue:5

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Drug Evaluation; Drug Tolerance; Fem

1986