norfloxacin has been researched along with Meningitis in 6 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Meningitis: Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic efficacy of the fluoroquinolone pefloxacin mesylate was compared with those of cefotaxime and chloramphenicol in a rabbit model of Escherichia coli meningitis." | 7.67 | Evaluation of pefloxacin in experimental Escherichia coli meningitis. ( Hackbarth, CJ; Sande, MA; Shibl, AM, 1986) |
| "Following a summary of the main bacteriological and pharmacokinetic properties of this new quinolone derivative, the author reviews the results obtained with pefloxacine in the treatment of urinary tract infection, gonococcal urethritis, and bronchopulmonary, surgical, gynaecological, bone, soft tissue, neuromeningeal and ENT infections." | 3.67 | [Pefloxacin: evaluation and clinical prospects]. ( Modaï, J, 1986) |
| "The therapeutic efficacy of the fluoroquinolone pefloxacin mesylate was compared with those of cefotaxime and chloramphenicol in a rabbit model of Escherichia coli meningitis." | 3.67 | Evaluation of pefloxacin in experimental Escherichia coli meningitis. ( Hackbarth, CJ; Sande, MA; Shibl, AM, 1986) |
| "Pefloxacin was given as the single drug (except in one case) to twenty-seven patients with a variety of infections (bone and/or joint: 8; respiratory tract: 6; urinary tract: 5; bacteremia: 4; meninges: 3; other: 1)." | 1.27 | [Pefloxacin: clinical experience]. ( Bertrand, A; Janbon, F; Jonquet, O; Jourdan, J; Santoni, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghadage, DP | 1 |
| Bal, AM | 1 |
| Modaï, J | 1 |
| Isaacs, RD | 1 |
| Ellis-Pegler, RB | 1 |
| Shibl, AM | 1 |
| Hackbarth, CJ | 1 |
| Sande, MA | 1 |
| Chomarat, M | 1 |
| Joulie, V | 1 |
| Fournier, G | 1 |
| Bouletreau, P | 1 |
| Flandrois, JP | 1 |
| Bertrand, A | 1 |
| Janbon, F | 1 |
| Jourdan, J | 1 |
| Jonquet, O | 1 |
| Santoni, A | 1 |
6 other studies available for norfloxacin and Meningitis
| Article | Year |
|---|---|
Antibiotic susceptibility pattern of Salmonella worthington isolated from neonates--a retrospective study.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Chloramphenicol; Ciprofloxacin; | 2002 |
[Pefloxacin: evaluation and clinical prospects].
Topics: Bacterial Infections; Evaluation Studies as Topic; Female; Humans; Lung Diseases; Male; Meningitis; | 1986 |
Successful treatment of Morganella morganii meningitis with pefloxacin mesylate.
Topics: Aged; Anti-Infective Agents; Enterobacteriaceae Infections; Female; Humans; Meningitis; Microbial Se | 1987 |
Evaluation of pefloxacin in experimental Escherichia coli meningitis.
Topics: Animals; Anti-Infective Agents; Cefotaxime; Chloramphenicol; Escherichia coli Infections; Humans; Me | 1986 |
[Pharmacokinetic study of pefloxacin in 37 hospital patients under resuscitation].
Topics: Humans; Intensive Care Units; Kinetics; Meningitis; Norfloxacin; Pefloxacin; Pneumonia; Risk; Sepsis | 1985 |
[Pefloxacin: clinical experience].
Topics: Acinetobacter Infections; Adult; Aged; Bacterial Infections; Enterobacteriaceae Infections; Enteroco | 1985 |