norfloxacin has been researched along with Malaria, Falciparum in 4 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyronaridine was the most effective gametocytocidal drug against P." | 1.31 | Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro. ( Auparakkitanon, S; Chavalitshewinkoon-Petmitr, P; Pongvilairat, G; Wilairat, P, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karad, SC | 1 |
| Purohit, VB | 1 |
| Thakor, P | 1 |
| Thakkar, VR | 1 |
| Raval, DK | 1 |
| Tripathi, KD | 1 |
| Sharma, AK | 1 |
| Valecha, N | 1 |
| Kulpati, DD | 1 |
| Chavalitshewinkoon-Petmitr, P | 1 |
| Pongvilairat, G | 1 |
| Auparakkitanon, S | 1 |
| Wilairat, P | 1 |
| McClean, KL | 1 |
| Hitchman, D | 1 |
| Shafran, SD | 1 |
1 trial available for norfloxacin and Malaria, Falciparum
| Article | Year |
|---|---|
Norfloxacin is inferior to chloroquine for falciparum malaria in northwestern Zambia: a comparative clinical trial.
Topics: Adult; Chloroquine; Drug Resistance; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; N | 1992 |
3 other studies available for norfloxacin and Malaria, Falciparum
| Article | Year |
|---|---|
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
Topics: Anti-Infective Agents; Antimalarials; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi; | 2016 |
Curative efficacy of norfloxacin in falciparum malaria.
Topics: Adolescent; Adult; Chloroquine; Drug Administration Schedule; Female; Humans; Malaria, Falciparum; M | 1993 |
Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro.
Topics: Amsacrine; Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Enzyme Inhibitors; Etopos | 2000 |