norfloxacin has been researched along with Liver Failure in 2 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the survival study, a dose-response effect of ciprofloxacin on survival was observed (ciprofloxacin: 10 mg/kg, 10%; 50 mg/kg, 26%; and 100 mg/kg, 35%) with the results in the 100-mg/kg-treated group being significant when compared with the 5% survival rate in saline-treated controls (P < ." | 5.30 | The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure. ( Assy, N; Gauthier, T; Kaita, KD; Meyers, AF; Minuk, GY; Zhang, M, 1998) |
| " In the survival study, a dose-response effect of ciprofloxacin on survival was observed (ciprofloxacin: 10 mg/kg, 10%; 50 mg/kg, 26%; and 100 mg/kg, 35%) with the results in the 100-mg/kg-treated group being significant when compared with the 5% survival rate in saline-treated controls (P < ." | 1.30 | The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure. ( Assy, N; Gauthier, T; Kaita, KD; Meyers, AF; Minuk, GY; Zhang, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| San-Juan, R | 1 |
| Aguado, JM | 1 |
| Lumbreras, C | 1 |
| Fortun, J | 1 |
| Len, O | 1 |
| Munoz, P | 1 |
| Montejo, M | 1 |
| Moreno, A | 1 |
| Cordero, E | 1 |
| Blanes, M | 1 |
| Ramos, A | 1 |
| Torre-Cisneros, J | 1 |
| López-Medrano, F | 1 |
| Carratala, J | 1 |
| Moreno, E | 1 |
| Kaita, KD | 1 |
| Assy, N | 1 |
| Gauthier, T | 1 |
| Zhang, M | 1 |
| Meyers, AF | 1 |
| Minuk, GY | 1 |
2 other studies available for norfloxacin and Liver Failure
| Article | Year |
|---|---|
Selective intestinal decontamination with fluoroquinolones for the prevention of early bacterial infections after liver transplantation.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Female; Fluoroquinolones; H | 2011 |
The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; DNA; Im | 1998 |