norfloxacin has been researched along with Leprosy in 3 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The treatment of mice with the smaller dosage ofloxacin, with pefloxacin, prothionamide, or dapsone uniformly resulted in a delay of multiplication of 4 months, compared to the multiplication of M." | 1.27 | Activity of ofloxacin against Mycobacterium leprae in the mouse. ( Beoletto, C; Grosset, JH; Guelpa-Lauras, CC; Perani, EG, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grosset, JH | 2 |
| Guelpa-Lauras, CC | 2 |
| Perani, EG | 2 |
| Beoletto, C | 1 |
| Pattyn, SR | 1 |
| Giroir, AM | 1 |
3 other studies available for norfloxacin and Leprosy
| Article | Year |
|---|---|
Activity of ofloxacin against Mycobacterium leprae in the mouse.
Topics: Animals; Anti-Bacterial Agents; Dapsone; Female; Leprosy; Mice; Mycobacterium leprae; Norfloxacin; O | 1988 |
Activity of ofloxacin and pefloxacin against Mycobacterium leprae in mice.
Topics: Animals; Drug Evaluation, Preclinical; Leprosy; Mice; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin | 1987 |
Activities of pefloxacin and ciprofloxacin against Mycobacterium leprae in the mouse.
Topics: Animals; Ciprofloxacin; Dapsone; Female; Half-Life; Kinetics; Leprosy; Mice; Mycobacterium leprae; N | 1987 |