norfloxacin has been researched along with Kidney Failure, Chronic in 10 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pefloxacin was used as monotherapy in 15 cases of peritonitis occurring in patients undergoing continuous ambulatory peritoneal dialysis (CAPD)." | 7.67 | [Treatment of peritonitis in kidney failure patients under continuous ambulatory peritoneal dialysis by pefloxacine. Results and pharmacokinetics]. ( Benevent, D; Denis, F; Lagarde, C; Mounier, M, 1987) |
| "Pefloxacin was used as monotherapy in 15 cases of peritonitis occurring in patients undergoing continuous ambulatory peritoneal dialysis (CAPD)." | 3.67 | [Treatment of peritonitis in kidney failure patients under continuous ambulatory peritoneal dialysis by pefloxacine. Results and pharmacokinetics]. ( Benevent, D; Denis, F; Lagarde, C; Mounier, M, 1987) |
| " For the other new quinolones, a decrease in glomerular filtration rate below 20-30 ml/min induces an increase in terminal half-life and a decrease in plasma and renal clearance, related to the degree of renal impairment." | 2.38 | Pharmacokinetics of quinolones in renal insufficiency. ( Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B, 1990) |
| " The mean serum elimination half-life was 8." | 1.27 | [Human and animal studies on the pharmacokinetics of norfloxacin in renal failure]. ( Akaba, K; Irikura, T; Kusajima, H; Miyahara, T; Saito, A; Shimada, J; Uchida, H, 1986) |
| " The mean apparent elimination half-life was 13." | 1.27 | Pharmacokinetics of pefloxacin in renal insufficiency. ( Bariety, J; Cunci, R; Jacquot, C; Montay, G, 1985) |
| "Norfloxacin is an antibacterial drug chiefly eliminated by the kidney and therefore useful in the treatment of urinary tract infections." | 1.27 | Pharmacokinetics of norfloxacin in chronic renal failure. ( Arrigo, G; Broccali, G; Cavaliere, G; D'Amico, G; Passarella, E, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eandi, M | 1 |
| Viano, I | 1 |
| Di Nola, F | 1 |
| Leone, L | 1 |
| Genazzani, E | 1 |
| Pascual, J | 1 |
| Orofino, L | 1 |
| Hernández, E | 1 |
| Liaño, F | 1 |
| García-González, R | 1 |
| Ortunño, J | 1 |
| Roy, A | 1 |
| Kalita, J | 1 |
| Gayathri, N | 1 |
| Shankar, SK | 1 |
| Misra, UK | 1 |
| Abad, A | 1 |
| López, P | 1 |
| Bauza, J | 1 |
| Fillastre, JP | 1 |
| Leroy, A | 1 |
| Moulin, B | 1 |
| Dhib, M | 1 |
| Borsa-Lebas, F | 1 |
| Humbert, G | 1 |
| Denis, F | 1 |
| Mounier, M | 1 |
| Lagarde, C | 1 |
| Benevent, D | 1 |
| Di Veroli, C | 1 |
| Carlizzi, G | 1 |
| Xagoraris, V | 1 |
| Shimada, J | 1 |
| Saito, A | 1 |
| Akaba, K | 1 |
| Miyahara, T | 1 |
| Kusajima, H | 1 |
| Uchida, H | 1 |
| Irikura, T | 1 |
| Montay, G | 1 |
| Jacquot, C | 1 |
| Bariety, J | 1 |
| Cunci, R | 1 |
| Arrigo, G | 1 |
| Cavaliere, G | 1 |
| D'Amico, G | 1 |
| Passarella, E | 1 |
| Broccali, G | 1 |
1 review available for norfloxacin and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration | 1990 |
9 other studies available for norfloxacin and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetics of norfloxacin in healthy volunteers and patients with renal and hepatic damage.
Topics: Adult; Aged; Anti-Infective Agents; Female; Hepatitis B; Humans; Kidney Failure, Chronic; Kinetics; | 1983 |
Subacute thyroiditis in a renal allograft recipient.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Biopsy, Needle; Cyclosporine; Escherichia coli Infe | 1996 |
Reversible neuropathy in chronic renal failure.
Topics: Axons; Demyelinating Diseases; Humans; Kidney Failure, Chronic; Male; Middle Aged; Motor Neuron Dise | 1998 |
Norfloxacin-induced positive direct antiglobulin test.
Topics: Adsorption; Aged; Anti-Infective Agents; Antibodies; Coombs Test; Erythrocytes; False Positive React | 1999 |
[Treatment of peritonitis in kidney failure patients under continuous ambulatory peritoneal dialysis by pefloxacine. Results and pharmacokinetics].
Topics: Adult; Aged; Anti-Infective Agents; Drug Tolerance; Humans; Kidney Failure, Chronic; Middle Aged; No | 1987 |
[Norfloxacin in chronic renal insufficiency].
Topics: Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Norfloxacin; Urinary Tract Infections | 1987 |
[Human and animal studies on the pharmacokinetics of norfloxacin in renal failure].
Topics: Administration, Oral; Adult; Aged; Animals; Bile; Female; Half-Life; Humans; Injections, Intravenous | 1986 |
Pharmacokinetics of pefloxacin in renal insufficiency.
Topics: Adult; Aged; Anti-Infective Agents; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Midd | 1985 |
Pharmacokinetics of norfloxacin in chronic renal failure.
Topics: Adolescent; Adult; Biological Availability; Female; Half-Life; Humans; Kidney; Kidney Failure, Chron | 1985 |