norfloxacin has been researched along with Kidney Diseases in 4 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients with a glomerular filtration rate of less than 30 ml/min require dosage reduction and we would recommend a reduction to half the usual dosage." | 1.27 | Pharmacokinetics of norfloxacin (MK 366) in patients with impaired kidney function--some preliminary results. ( Asscher, AW; Hughes, PJ; Webb, DB, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A | 1 |
| Tam, KY | 1 |
| Hughes, PJ | 1 |
| Webb, DB | 1 |
| Asscher, AW | 1 |
| Höffler, D | 1 |
| Schäfer, I | 1 |
| Koeppe, P | 1 |
| Sörgel, F | 1 |
| Holmes, B | 1 |
| Brogden, RN | 1 |
| Richards, DM | 1 |
1 review available for norfloxacin and Kidney Diseases
| Article | Year |
|---|---|
Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Topics: Antifungal Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial | 1985 |
3 other studies available for norfloxacin and Kidney Diseases
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological | 2010 |
Pharmacokinetics of norfloxacin (MK 366) in patients with impaired kidney function--some preliminary results.
Topics: Anti-Infective Agents, Urinary; Glomerular Filtration Rate; Half-Life; Humans; Kidney Diseases; Kine | 1984 |
Pharmacokinetics of pefloxacin in normal and impaired renal function.
Topics: Adult; Anti-Bacterial Agents; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Male; Nor | 1988 |