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norfloxacin and Innate Inflammatory Response

norfloxacin has been researched along with Innate Inflammatory Response in 10 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Research Excerpts

ExcerptRelevanceReference
" In this study, the role of norfloxacin on Leptospira-induced inflammation was investigated."8.12Norfloxacin suppresses Leptospira-induced inflammation through inhibiting p65 and ERK phosphorylation and NLRP3 inflammasome activation. ( Cao, Y; Chen, X; Wu, D; Xie, X; Zhang, W, 2022)
" In this study, the role of norfloxacin on Leptospira-induced inflammation was investigated."4.12Norfloxacin suppresses Leptospira-induced inflammation through inhibiting p65 and ERK phosphorylation and NLRP3 inflammasome activation. ( Cao, Y; Chen, X; Wu, D; Xie, X; Zhang, W, 2022)
"Norfloxacin is a gram-negative bactericidal drug able to maintain low endotoxin levels and stimulate IL-10 production."1.40Role of interleukin 10 in norfloxacin prevention of luminal free endotoxin translocation in mice with cirrhosis. ( Francés, R; Giménez, P; Gómez-Hurtado, I; González-Navajas, JM; Moratalla, A; Moya-Pérez, Á; Peiró, G; Sanz, Y; Such, J; Zapater, P, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Kalkhambkar, RG1
Kulkarni, GM1
Kamanavalli, CM1
Premkumar, N1
Asdaq, SM1
Sun, CM1
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Xie, X1
Zhang, W2
Chen, X1
Wu, D1
Cao, Y1
Li, J1
Moturi, KR1
Wang, L1
Zhang, K1
Yu, C1
Saffouri, GB1
Wittich, CM1
Gómez-Hurtado, I1
Moratalla, A1
Moya-Pérez, Á1
Peiró, G1
Zapater, P1
González-Navajas, JM1
Giménez, P1
Such, J1
Sanz, Y1
Francés, R1
Zhang, S1
Wang, Y1
Jin, Z1
Wang, X1
Zhang, J1
Zhang, Y1
Alagarsamy, V1
Murugananthan, G1
Venkateshperumal, R1
Thomas, JM1
Swanson, NA1
Comhaire, FH1

Other Studies

10 other studies available for norfloxacin and Innate Inflammatory Response

ArticleYear
Synthesis and biological activities of some new fluorinated coumarins and 1-aza coumarins.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Analgesics; Animals; Aza Compounds; Bacteria; Coumarins; Drug Design; Fluorine; Fungi; Inflammation;

2008
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Norfloxacin suppresses Leptospira-induced inflammation through inhibiting p65 and ERK phosphorylation and NLRP3 inflammasome activation.
    Microbial pathogenesis, 2022, Volume: 162

    Topics: Extracellular Signal-Regulated MAP Kinases; Humans; Inflammasomes; Inflammation; Interleukin-1beta;

2022
Gut derived-endotoxin contributes to inflammation in severe ischemic acute kidney injury.
    BMC nephrology, 2019, 01-11, Volume: 20, Issue:1

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Bacterial Translocation; Endotoxemia; Endotoxin

2019
83-year-old man with abdominal swelling and lower extremity edema.
    Mayo Clinic proceedings, 2013, Volume: 88, Issue:10

    Topics: Abdominal Cavity; Aged, 80 and over; Anti-Infective Agents; Ascites; Cefotaxime; Diagnosis, Differen

2013
Role of interleukin 10 in norfloxacin prevention of luminal free endotoxin translocation in mice with cirrhosis.
    Journal of hepatology, 2014, Volume: 61, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Bacterial Translocation; Endotoxins; Escherichia coli; Inflammation;

2014
Synthesis and biodistribution of a novel (⁹⁹m)TcN complex of norfloxacin dithiocarbamate as a potential agent for bacterial infection imaging.
    Bioconjugate chemistry, 2011, Mar-16, Volume: 22, Issue:3

    Topics: Animals; Bacterial Infections; Drug Stability; Electrophoresis, Paper; Inflammation; Isotope Labelin

2011
Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-methyl-3-substituted quinazolin-4-(3H)-ones.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:12

    Topics: Administration, Oral; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ster

2003
Treatment of perichondritis with a quinolone derivative--norfloxacin.
    The Journal of dermatologic surgery and oncology, 1988, Volume: 14, Issue:4

    Topics: Carcinoma, Basal Cell; Cartilage Diseases; Ear Cartilage; Ear Neoplasms; Ear, External; Humans; Infl

1988
Concentration of pefloxacine in split ejaculates of patients with chronic male accessory gland infection.
    The Journal of urology, 1987, Volume: 138, Issue:4

    Topics: Adult; Chronic Disease; Exocrine Glands; Genital Diseases, Male; Humans; Infertility, Male; Inflamma

1987