norfloxacin has been researched along with Hematochezia in 11 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Hematochezia: The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Once weekly ciprofloxacin was as effective as daily norfloxacin for the prevention of SBP in cirrhotic patients with ascites." | 9.27 | Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial. ( Jang, JY; Jung, YK; Kim, BI; Kim, HS; Kim, YS; Lee, YR; Park, SY; Seo, YS; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2018) |
| "Selective intestinal decontamination with norfloxacin is useful in the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding." | 9.08 | Parenteral antibiotic prophylaxis of bacterial infections does not improve cost-efficacy of oral norfloxacin in cirrhotic patients with gastrointestinal bleeding. ( Balanzó, J; Guarner, C; Kolle, L; Novella, MT; Ortiz, J; Pamplona, J; Sàbat, M; Sainz, S; Soriano, G; Torras, J; Villanueva, C, 1998) |
| "To assess the efficacy of selective intestinal decontamination with norfloxacin in the prevention of bacterial infections in cirrhotic patients with gastrointestinal hemorrhage, 119 patients were included in a prospective randomized study." | 9.07 | Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage. ( Anguera, A; Balanzó, J; Cussó, X; González, D; Guarner, C; Sainz, S; Soriano, G; Tomás, A; Torras, X; Villanueva, C, 1992) |
| "Once weekly ciprofloxacin was as effective as daily norfloxacin for the prevention of SBP in cirrhotic patients with ascites." | 5.27 | Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial. ( Jang, JY; Jung, YK; Kim, BI; Kim, HS; Kim, YS; Lee, YR; Park, SY; Seo, YS; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2018) |
| "Oral norfloxacin is the standard of therapy in the prophylaxis of bacterial infections in cirrhotic patients with gastrointestinal hemorrhage." | 5.12 | Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage. ( Arroyo, V; Durandez, R; Fernández, J; Gómez, C; Guarner, C; Navasa, M; Planas, R; Ruiz del Arbol, L; Serradilla, R, 2006) |
| "Selective intestinal decontamination with norfloxacin is useful in the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding." | 5.08 | Parenteral antibiotic prophylaxis of bacterial infections does not improve cost-efficacy of oral norfloxacin in cirrhotic patients with gastrointestinal bleeding. ( Balanzó, J; Guarner, C; Kolle, L; Novella, MT; Ortiz, J; Pamplona, J; Sàbat, M; Sainz, S; Soriano, G; Torras, J; Villanueva, C, 1998) |
| "To assess the efficacy of selective intestinal decontamination with norfloxacin in the prevention of bacterial infections in cirrhotic patients with gastrointestinal hemorrhage, 119 patients were included in a prospective randomized study." | 5.07 | Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage. ( Anguera, A; Balanzó, J; Cussó, X; González, D; Guarner, C; Sainz, S; Soriano, G; Tomás, A; Torras, X; Villanueva, C, 1992) |
| " For primary prophylaxis, short-term antibiotic treatment (oral norfloxacin or ciprofloxacin) is indicated in cirrhotic patients (with or without ascites) admitted with gastrointestinal haemorrhage (variceal or non-variceal)." | 4.84 | [Bacterial infections in liver cirrhosis]. ( Farkas, A; Papp, M; Tornai, I; Udvardy, M, 2007) |
| "Due to a high number of bacterial infections antibiotics administration has been indicated in these patients." | 2.71 | [Factors participating in development of bleeding varices in portal hypertension. Part I: bacterial infection and comparison of intravenous and peroral antibiotics effects--a randomised study]. ( Dastych, M; Díte, P; Husová, L; Juránková, J; Lata, J; Príbramská, V; Senkyrík, M, 2004) |
| "To determine the prevalence of bacterial infection in patients admitted to hospital with variceal bleeding in comparison with patients with liver cirrhosis admitted because of another reason." | 2.71 | Variceal bleeding in portal hypertension: bacterial infection and comparison of efficacy of intravenous and per-oral application of antibiotics--a randomized trial. ( Dastych, M; Díte, P; Husová, L; Juránková, J; Kroupa, R; Lata, J; Príbramská, V; Senkyrík, M, 2005) |
| "Bacterial infections are common in cirrhotic patients with acute variceal bleeding, occurring in 20% within 48 h." | 2.50 | Role of prophylactic antibiotics in cirrhotic patients with variceal bleeding. ( Lee, YY; Mahadeva, S; Tee, HP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yim, HJ | 1 |
| Suh, SJ | 1 |
| Jung, YK | 1 |
| Yim, SY | 1 |
| Seo, YS | 1 |
| Lee, YR | 1 |
| Park, SY | 1 |
| Jang, JY | 1 |
| Kim, YS | 1 |
| Kim, HS | 1 |
| Kim, BI | 1 |
| Um, SH | 1 |
| Lee, YY | 1 |
| Tee, HP | 1 |
| Mahadeva, S | 1 |
| Salerno, F | 1 |
| La Mura, V | 1 |
| Lata, J | 2 |
| Juránková, J | 2 |
| Husová, L | 2 |
| Senkyrík, M | 2 |
| Díte, P | 2 |
| Dastych, M | 2 |
| Príbramská, V | 2 |
| Kroupa, R | 1 |
| Fernández, J | 1 |
| Ruiz del Arbol, L | 1 |
| Gómez, C | 1 |
| Durandez, R | 1 |
| Serradilla, R | 1 |
| Guarner, C | 3 |
| Planas, R | 1 |
| Arroyo, V | 1 |
| Navasa, M | 1 |
| Papp, M | 1 |
| Farkas, A | 1 |
| Udvardy, M | 1 |
| Tornai, I | 1 |
| Imperiale, TF | 1 |
| Esber, EJ | 1 |
| Sàbat, M | 1 |
| Kolle, L | 1 |
| Soriano, G | 2 |
| Ortiz, J | 1 |
| Pamplona, J | 1 |
| Novella, MT | 1 |
| Villanueva, C | 2 |
| Sainz, S | 2 |
| Torras, J | 1 |
| Balanzó, J | 2 |
| Tomás, A | 1 |
| Torras, X | 1 |
| González, D | 1 |
| Anguera, A | 1 |
| Cussó, X | 1 |
| Grangé, JD | 1 |
| Amiot, X | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis in Patients With Acute Variceal Bleeding[NCT00838864] | Phase 4 | 79 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| Rifaximin Versus Norfloxacin in the Primary Prophylaxis of Spontaneous Bacterial Peritonitis[NCT04159870] | Phase 3 | 322 participants (Anticipated) | Interventional | 2019-11-05 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for norfloxacin and Hematochezia
| Article | Year |
|---|---|
Role of prophylactic antibiotics in cirrhotic patients with variceal bleeding.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Ciprofloxacin; Endoscopy; Esoph | 2014 |
[Bacterial infections in liver cirrhosis].
Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ascites; | 2007 |
[Prophylaxis of infectious complications by selective digestive bacterial decontamination in patients with cirrhosis].
Topics: Anti-Bacterial Agents; Ascitic Fluid; Bacterial Infections; Decontamination; Digestive System Diseas | 1992 |
6 trials available for norfloxacin and Hematochezia
| Article | Year |
|---|---|
Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Ascites; Bacterial Infections; Ciprofloxacin; Disease-Free Survi | 2018 |
[Factors participating in development of bleeding varices in portal hypertension. Part I: bacterial infection and comparison of intravenous and peroral antibiotics effects--a randomised study].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Bacterial I | 2004 |
Variceal bleeding in portal hypertension: bacterial infection and comparison of efficacy of intravenous and per-oral application of antibiotics--a randomized trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Bacterial I | 2005 |
Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Ba | 2006 |
Parenteral antibiotic prophylaxis of bacterial infections does not improve cost-efficacy of oral norfloxacin in cirrhotic patients with gastrointestinal bleeding.
Topics: Administration, Oral; Aged; Anti-Infective Agents; Bacterial Infections; Ceftriaxone; Cephalosporins | 1998 |
Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage.
Topics: Adult; Aged; Bacterial Infections; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Mal | 1992 |
Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage.
Topics: Adult; Aged; Bacterial Infections; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Mal | 1992 |
Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage.
Topics: Adult; Aged; Bacterial Infections; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Mal | 1992 |
Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage.
Topics: Adult; Aged; Bacterial Infections; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Mal | 1992 |
2 other studies available for norfloxacin and Hematochezia
| Article | Year |
|---|---|
Treatment of Spontaneous Bacterial Peritonitis.
Topics: Age Factors; Albumins; Anti-Bacterial Agents; Antibiotic Prophylaxis; Ascites; Bilirubin; Drug Resis | 2015 |
Preventing infection in cirrhotics with gastrointestinal hemorrhage.
Topics: Bacteremia; Bacterial Infections; Biometry; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; No | 1993 |