norfloxacin has been researched along with Gram-Positive Bacterial Infections in 9 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Gram-Positive Bacterial Infections: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of a combination regimen using norfloxacin (NFLX) and amphotericin B (AMPH-B) for prevention of infections in patients with acute leukemia being treated by remission-induction chemotherapy in a randomized, controlled trial was studied." | 9.07 | Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B. ( Dan, K; Nomura, T; Yamada, T, 1993) |
| "The effect of a combination regimen using norfloxacin (NFLX) and amphotericin B (AMPH-B) for prevention of infections in patients with acute leukemia being treated by remission-induction chemotherapy in a randomized, controlled trial was studied." | 5.07 | Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B. ( Dan, K; Nomura, T; Yamada, T, 1993) |
| "To determine the relative importance of temperate bacteriophage in the horizontal gene transfer of fitness and virulence determinants of Enterococcus faecalis, a panel of 47 bacteremia isolates were treated with the inducing agents mitomycin C, norfloxacin, and UV radiation." | 3.76 | Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages. ( Darby, AC; Edwards, C; Hall, N; Horsburgh, MJ; Kenny, JG; Shankar, J; Yasmin, A, 2010) |
| " Urine samples were taken every 2 h during the whole dosing interval of the particular antibiotic." | 1.33 | Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model. ( Bedenic, B; Bubonja, M; Budimir, A; Topic, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Makawana, JA | 1 |
| Mungra, DC | 1 |
| Patel, MP | 1 |
| Patel, RG | 1 |
| Koh, JJ | 2 |
| Lin, S | 2 |
| Aung, TT | 2 |
| Lim, F | 2 |
| Zou, H | 2 |
| Bai, Y | 1 |
| Li, J | 2 |
| Lin, H | 1 |
| Pang, LM | 1 |
| Koh, WL | 1 |
| Salleh, SM | 1 |
| Lakshminarayanan, R | 2 |
| Zhou, L | 1 |
| Qiu, S | 1 |
| Pervushin, K | 1 |
| Verma, C | 2 |
| Tan, DT | 2 |
| Cao, D | 2 |
| Liu, S | 2 |
| Beuerman, RW | 2 |
| Wang, L | 1 |
| Wang, Y | 1 |
| Ren, L | 1 |
| Bert, F | 1 |
| Leflon-Guibout, V | 1 |
| Le Grand, J | 1 |
| Bourdon, N | 1 |
| Nicolas-Chanoine, MH | 1 |
| Yasmin, A | 1 |
| Kenny, JG | 1 |
| Shankar, J | 1 |
| Darby, AC | 1 |
| Hall, N | 1 |
| Edwards, C | 1 |
| Horsburgh, MJ | 1 |
| Orogade, AA | 1 |
| Akuse, RM | 1 |
| Bedenic, B | 1 |
| Topic, M | 1 |
| Budimir, A | 1 |
| Bubonja, M | 1 |
| Yamada, T | 1 |
| Dan, K | 1 |
| Nomura, T | 1 |
| Broun, ER | 1 |
| Wheat, JL | 1 |
| Kneebone, PH | 1 |
| Sundblad, K | 1 |
| Hromas, RA | 1 |
| Tricot, G | 1 |
1 review available for norfloxacin and Gram-Positive Bacterial Infections
| Article | Year |
|---|---|
[Emergence of vancomycin-dependent enterococci following glycopeptide therapy: case report and review].
Topics: Bacterial Proteins; Bacteriuria; Carbon-Oxygen Ligases; Cecal Diseases; Ceftriaxone; Citrobacter fre | 2009 |
2 trials available for norfloxacin and Gram-Positive Bacterial Infections
| Article | Year |
|---|---|
Prevention of bacterial and fungal infections in acute leukemia patients: a new and potent combination of oral norfloxacin and amphotericin B.
Topics: Administration, Oral; Adult; Amphotericin B; Antineoplastic Agents; Bacterial Infections; Drug Combi | 1993 |
Randomized trial of the addition of gram-positive prophylaxis to standard antimicrobial prophylaxis for patients undergoing autologous bone marrow transplantation.
Topics: Acyclovir; Adult; Bacteremia; Bone Marrow Transplantation; Female; Fever; Fluconazole; Gram-Positive | 1994 |
6 other studies available for norfloxacin and Gram-Positive Bacterial Infections
| Article | Year |
|---|---|
Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Candida albicans; Fungi; Gram-Negative Bacte | 2011 |
Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Cell Membrane; Drug Resistance, Multiple, Bacterial; Gr | 2015 |
Symmetrically Substituted Xanthone Amphiphiles Combat Gram-Positive Bacterial Resistance with Enhanced Membrane Selectivity.
Topics: Animals; Anti-Bacterial Agents; Cornea; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Pos | 2017 |
Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages.
Topics: Anti-Bacterial Agents; Bacteremia; Bacteriophages; DNA Fingerprinting; DNA, Viral; Electrophoresis, | 2010 |
Changing patterns in sensitivity of causative organisms of septicaemia in children: the need for quinolones.
Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Gr | 2004 |
Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.
Topics: Acetamides; Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; | 2006 |