norfloxacin has been researched along with Gonorrhea in 29 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Gonorrhea: Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty six males with gonococcal urethritis were administered 600 mg of norfloxacin (NFLX) daily for 7 days, before the effects were examined." | 9.06 | [Treatment of gonococcal urethritis with norfloxacin]. ( Asaka, H; Asano, H; Fukatsu, H; Mitsuya, H; Murase, T; Obata, K; Okamura, K; Otani, S; Segawa, A; Yoshida, K, 1989) |
| "Thirty patients with acute urethritis were treated with short-term administration of norfloxacin." | 9.06 | [Clinical effectiveness of short-term administration of norfloxacin in acute urethritis]. ( Fukui, I; Goto, S; Kihara, K; Mizuo, T; Oshima, H, 1986) |
| "In 12 recent clinical studies, norfloxacin given in various dosage regimens was shown to be highly effective in treating 1,588 gonococcal infections in 1,486 patients." | 7.76 | Norfloxacin in the treatment of gonorrhea due to penicillinase and non-penicillinase producing Neisseria gonorrheae: a review. ( Lee, CT; Wong, EC, 1988) |
| "Fifteen male outpatients with uncomplicated gonococcal urethritis were treated by a single oral dose of norfloxacin (800 mg)." | 7.67 | Clinical trial of norfloxacin in the treatment of uncomplicated gonococcal urethritis: preliminary report. ( Cristiano, P, 1989) |
| "In an open study, 70 patients with uncomplicated anogenital Neisseria gonorrhoeae infection were evaluated to determine the efficacy and safety of a single oral dose of norfloxacin (800 mg)." | 7.67 | Norfloxacin in the therapy of uncomplicated gonorrhea. ( Draker, J; Romanowski, B; Tsianco, MC; Wood, H, 1986) |
| "Thirty male patients with gonorrheal urethritis were treated with norfloxacin (NFLX) at our urological ward between May and July, 1984, and clinically evaluated." | 7.67 | [Bacteriological and clinical evaluation of norfloxacin in male gonorrheal urethritis]. ( Okazaki, T, 1987) |
| "Norfloxacin, a new quinolinecarboxylic acid derivative, was administered to 30 male patients with gonococcal urethritis at a daily dose of 600 mg for 7-21 days." | 7.67 | [Clinical evaluation of norfloxacin in gonococcal urethritis]. ( Jinbo, S; Mashimo, T; Miki, M; Yamanaka, H, 1986) |
| "Norfloxacin treatment failure was not related to drug resistance or to insufficient absorption of the drug." | 6.66 | Norfloxacin versus thiamphenicol for treatment of uncomplicated gonorrhea in Rwanda. ( Bogaerts, J; Martinez Tello, W; Piot, P; Vandepitte, J; Verbist, L, 1987) |
| " Ciprofloxacin is effective in single dosage against urogenital gonococcal infections, and probably also against rectal and pharyngeal infections." | 6.37 | Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis. ( Oriel, JD, 1986) |
| "Fifty six males with gonococcal urethritis were administered 600 mg of norfloxacin (NFLX) daily for 7 days, before the effects were examined." | 5.06 | [Treatment of gonococcal urethritis with norfloxacin]. ( Asaka, H; Asano, H; Fukatsu, H; Mitsuya, H; Murase, T; Obata, K; Okamura, K; Otani, S; Segawa, A; Yoshida, K, 1989) |
| "Thirty patients with acute urethritis were treated with short-term administration of norfloxacin." | 5.06 | [Clinical effectiveness of short-term administration of norfloxacin in acute urethritis]. ( Fukui, I; Goto, S; Kihara, K; Mizuo, T; Oshima, H, 1986) |
| "In 12 recent clinical studies, norfloxacin given in various dosage regimens was shown to be highly effective in treating 1,588 gonococcal infections in 1,486 patients." | 3.76 | Norfloxacin in the treatment of gonorrhea due to penicillinase and non-penicillinase producing Neisseria gonorrheae: a review. ( Lee, CT; Wong, EC, 1988) |
| "or t." | 3.76 | World-wide clinical experience with norfloxacin: efficacy and safety. ( Corrado, M; Hoagland, V; Sabbaj, J; Wang, C, 1986) |
| "Fifteen male outpatients with uncomplicated gonococcal urethritis were treated by a single oral dose of norfloxacin (800 mg)." | 3.67 | Clinical trial of norfloxacin in the treatment of uncomplicated gonococcal urethritis: preliminary report. ( Cristiano, P, 1989) |
| "In an open study, 70 patients with uncomplicated anogenital Neisseria gonorrhoeae infection were evaluated to determine the efficacy and safety of a single oral dose of norfloxacin (800 mg)." | 3.67 | Norfloxacin in the therapy of uncomplicated gonorrhea. ( Draker, J; Romanowski, B; Tsianco, MC; Wood, H, 1986) |
| "Thirty male patients with gonorrheal urethritis were treated with norfloxacin (NFLX) at our urological ward between May and July, 1984, and clinically evaluated." | 3.67 | [Bacteriological and clinical evaluation of norfloxacin in male gonorrheal urethritis]. ( Okazaki, T, 1987) |
| "Norfloxacin, a new quinolinecarboxylic acid derivative, was administered to 30 male patients with gonococcal urethritis at a daily dose of 600 mg for 7-21 days." | 3.67 | [Clinical evaluation of norfloxacin in gonococcal urethritis]. ( Jinbo, S; Mashimo, T; Miki, M; Yamanaka, H, 1986) |
| "We studied the basic and clinical effects of norfloxacin (NFLX) in 120 patients with gonococcal infections (110 men with urethritis and 10 women with cervicitis)--all residents at Sapporo City; and epidemiologically analyzed the sources of their infections." | 3.67 | [Epidemiologic and therapeutic study on gonococcal infections--clinical efficacy of norfloxacin]. ( Gohro, T; Henmi, I; Hirose, T; Igawa, K; Inoke, T; Kumamoto, Y; Sakai, S; Tabata, S; Tazuki, J; Tsunekawa, T, 1986) |
| "Norfloxacin treatment failure was not related to drug resistance or to insufficient absorption of the drug." | 2.66 | Norfloxacin versus thiamphenicol for treatment of uncomplicated gonorrhea in Rwanda. ( Bogaerts, J; Martinez Tello, W; Piot, P; Vandepitte, J; Verbist, L, 1987) |
| " Ciprofloxacin is effective in single dosage against urogenital gonococcal infections, and probably also against rectal and pharyngeal infections." | 2.37 | Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis. ( Oriel, JD, 1986) |
| "Norfloxacin is a quinolone derivative with demonstrated activity against Neisseria gonorrhoeae." | 1.27 | Norfloxacin in the therapy of gonococcal infections. ( Romanowski, B, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (72.41) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dupin, N | 1 |
| Gerhardt, P | 1 |
| Crider, SR | 1 |
| Colby, SD | 1 |
| Miller, LK | 1 |
| Harrison, WO | 1 |
| Kerbs, SB | 1 |
| Berg, SW | 1 |
| Jain, SK | 1 |
| Kulkarni, MG | 2 |
| Banker, DD | 1 |
| Tanaka, M | 2 |
| Kumazawa, J | 1 |
| Matsumoto, T | 1 |
| Kobayashi, I | 2 |
| Bogaerts, J | 2 |
| Tello, WM | 1 |
| Akingeneye, J | 1 |
| Mukantabana, V | 1 |
| Van Dyck, E | 1 |
| Piot, P | 2 |
| Mason, PR | 1 |
| Gwanzura, L | 1 |
| Latif, AS | 1 |
| Marowa, E | 1 |
| Ray, S | 1 |
| Katzenstein, DA | 1 |
| Bhalla, P | 1 |
| Sethi, K | 1 |
| Reddy, BS | 1 |
| Mathur, MD | 1 |
| Pai, A | 1 |
| Koppikar, GV | 1 |
| Tunoe, H | 1 |
| Mochida, O | 1 |
| Kanayama, A | 1 |
| Saika, T | 1 |
| Naito, S | 1 |
| Melby, K | 1 |
| Faegri, A | 1 |
| Mitsuya, H | 1 |
| Asaka, H | 1 |
| Segawa, A | 1 |
| Fukatsu, H | 1 |
| Otani, S | 1 |
| Yoshida, K | 1 |
| Okamura, K | 1 |
| Murase, T | 1 |
| Asano, H | 1 |
| Obata, K | 1 |
| Cristiano, P | 1 |
| O-Prasertsawat, P | 1 |
| Phiromsawat, S | 1 |
| Srisupandit, S | 1 |
| Sugkraroek, P | 1 |
| Pongthai, S | 1 |
| Panikabutra, K | 1 |
| Lee, CT | 2 |
| Ho, B | 1 |
| Bamberg, P | 1 |
| Romanowski, B | 2 |
| Wood, H | 1 |
| Draker, J | 1 |
| Tsianco, MC | 1 |
| Martinez Tello, W | 1 |
| Verbist, L | 1 |
| Vandepitte, J | 1 |
| Chaisilwattana, P | 1 |
| Roongpisuthipong, A | 1 |
| Bhiraleus, P | 1 |
| Okazaki, T | 1 |
| Wong, EC | 1 |
| Dey, SK | 1 |
| Banerjee, PK | 1 |
| Lee, C | 1 |
| Ronald, AR | 1 |
| Kaplowitz, LG | 1 |
| Vishniavsky, N | 1 |
| Evans, T | 1 |
| Vartivarian, S | 1 |
| Dalton, H | 1 |
| Simpson, M | 1 |
| Gruninger, RP | 1 |
| Wang, C | 1 |
| Sabbaj, J | 1 |
| Corrado, M | 1 |
| Hoagland, V | 1 |
| Oriel, JD | 1 |
| Kihara, K | 1 |
| Mizuo, T | 1 |
| Fukui, I | 1 |
| Oshima, H | 1 |
| Goto, S | 1 |
| Miki, M | 1 |
| Jinbo, S | 1 |
| Mashimo, T | 1 |
| Yamanaka, H | 1 |
| Sakai, S | 1 |
| Kumamoto, Y | 1 |
| Tsunekawa, T | 1 |
| Hirose, T | 1 |
| Tabata, S | 1 |
| Gohro, T | 1 |
| Inoke, T | 1 |
| Igawa, K | 1 |
| Tazuki, J | 1 |
| Henmi, I | 1 |
| Holmes, B | 1 |
| Brogden, RN | 1 |
| Richards, DM | 1 |
5 reviews available for norfloxacin and Gonorrhea
| Article | Year |
|---|---|
Norfloxacin in the treatment of gonorrhea due to penicillinase and non-penicillinase producing Neisseria gonorrheae: a review.
Topics: Adolescent; Adult; Clinical Trials as Topic; Female; Gonorrhea; Humans; Male; Middle Aged; Neisseria | 1988 |
Norfloxacin: its potential in clinical practice.
Topics: Bacterial Infections; Diarrhea; Gonorrhea; Humans; Neutropenia; Norfloxacin; Travel; Urinary Tract I | 1987 |
World-wide clinical experience with norfloxacin: efficacy and safety.
Topics: Acute Disease; Agranulocytosis; Bacterial Infections; Clinical Trials as Topic; Diarrhea; Gastroente | 1986 |
Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis.
Topics: 4-Quinolones; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chlamydia Infections; Chlamydia | 1986 |
Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Topics: Antifungal Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial | 1985 |
7 trials available for norfloxacin and Gonorrhea
| Article | Year |
|---|---|
[Treatment of gonococcal urethritis with norfloxacin].
Topics: Adult; Clinical Trials as Topic; Gonorrhea; Humans; Male; Middle Aged; Multicenter Studies as Topic; | 1989 |
Single dose oral norfloxacin or intramuscular spectinomycin to treat gonorrhoea (PPNG and non-PPNG infections): analysis of efficacy and patient preference.
Topics: Administration, Oral; Adolescent; Adult; Female; Gonorrhea; Humans; Injections, Intramuscular; Male; | 1988 |
Norfloxacin versus thiamphenicol for treatment of uncomplicated gonorrhea in Rwanda.
Topics: Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Th | 1987 |
Norfloxacin in the treatment of gonorrhea due to penicillinase and non-penicillinase producing Neisseria gonorrheae: a review.
Topics: Adolescent; Adult; Clinical Trials as Topic; Female; Gonorrhea; Humans; Male; Middle Aged; Neisseria | 1988 |
Norfloxacin in the treatment of uncomplicated gonococcal infections.
Topics: Adult; Aged; Ampicillin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combi | 1987 |
World-wide clinical experience with norfloxacin: efficacy and safety.
Topics: Acute Disease; Agranulocytosis; Bacterial Infections; Clinical Trials as Topic; Diarrhea; Gastroente | 1986 |
[Clinical effectiveness of short-term administration of norfloxacin in acute urethritis].
Topics: Acute Disease; Adult; Drug Administration Schedule; Gonorrhea; Humans; Male; Middle Aged; Norfloxaci | 1986 |
19 other studies available for norfloxacin and Gonorrhea
| Article | Year |
|---|---|
[Diagnosis of sexually transmitted diseases: case studies].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Carcinoma, Squamous Cell; Diagn | 2013 |
Treatment of penicillin-resistant Neisseria gonorrhoeae with oral norfloxacin.
Topics: Administration, Oral; Anti-Bacterial Agents; Drug Tolerance; Gonorrhea; Humans; Male; Nalidixic Acid | 1984 |
Antibiotic susceptibility pattern of gonococcal isolates.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria | 1994 |
High prevalence of Neisseria gonorrhoeae strains with reduced susceptibility to fluoroquinolones in Japan.
Topics: Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbi | 1994 |
Effectiveness of norfloxacin and ofloxacin for treatment of gonorrhoea and decrease of in vitro susceptibility to quinolones over time in Rwanda.
Topics: Administration, Oral; Adult; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria gonorrho | 1993 |
Antimicrobial resistance in gonococci isolated from patients and from commercial sex workers in Harare, Zimbabwe.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactam Resistance; Ciprofloxacin; Drug Resistance | 1997 |
Antimicrobial susceptibility and plasmid profile of Neisseria gonorrhoeae in India (New Delhi).
Topics: Adolescent; Adult; Anti-Infective Agents; Drug Resistance, Microbial; Gonorrhea; Humans; India; Male | 1998 |
Antibiotics sensitivity pattern of N. gonorrhoeae with special emphasis on norfloxacin and ciprofloxacin.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Gonorrhea; Humans; Ma | 1999 |
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates.
Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluo | 2000 |
The in vitro activity of norfloxacin, ofloxacin and ciprofloxacin and other antibiotics in current use against Neisseria gonorrhoeae.
Topics: Ampicillin; Ampicillin Resistance; Ciprofloxacin; Doxycycline; Drug Resistance, Microbial; Gonorrhea | 1989 |
Clinical trial of norfloxacin in the treatment of uncomplicated gonococcal urethritis: preliminary report.
Topics: Adult; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Pen | 1989 |
The efficacy between spectinomycin and norfloxacin in the treatment of uncomplicated gonorrhoeae.
Topics: Female; Gonorrhea; Humans; Norfloxacin; Prospective Studies; Random Allocation; Spectinomycin | 1987 |
Norfloxacin in the therapy of gonococcal infections.
Topics: Administration, Oral; Adolescent; Adult; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Nor | 1986 |
Norfloxacin in the therapy of uncomplicated gonorrhea.
Topics: Child; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxa | 1986 |
Norfloxacin in the treatment of uncomplicated gonorrhoeae in nonpregnant females.
Topics: Administration, Oral; Adult; Drug Administration Schedule; Female; Gonorrhea; Humans; Male; Neisseri | 1987 |
[Bacteriological and clinical evaluation of norfloxacin in male gonorrheal urethritis].
Topics: Adolescent; Adult; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Norfl | 1987 |
Treatment of uncomplicated gonorrhoea in male with norfloxacin.
Topics: Adolescent; Adult; Child; Gonorrhea; Humans; Male; Middle Aged; Norfloxacin | 1988 |
[Clinical evaluation of norfloxacin in gonococcal urethritis].
Topics: Adult; Drug Administration Schedule; Drug Evaluation; Gonorrhea; Humans; Male; Middle Aged; Norfloxa | 1986 |
[Epidemiologic and therapeutic study on gonococcal infections--clinical efficacy of norfloxacin].
Topics: Adolescent; Adult; Aged; Chlamydia Infections; Chlamydia trachomatis; Drug Evaluation; Drug Resistan | 1986 |