Page last updated: 2024-11-01

norfloxacin and Dysentery, Bacillary

norfloxacin has been researched along with Dysentery, Bacillary in 14 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Dysentery, Bacillary: DYSENTERY caused by gram-negative rod-shaped enteric bacteria (ENTEROBACTERIACEAE), most often by the genus SHIGELLA. Shigella dysentery, Shigellosis, is classified into subgroups according to syndrome severity and the infectious species. Group A: SHIGELLA DYSENTERIAE (severest); Group B: SHIGELLA FLEXNERI; Group C: SHIGELLA BOYDII; and Group D: SHIGELLA SONNEI (mildest).

Research Excerpts

ExcerptRelevanceReference
" Norfloxacin is safe and effective and showed no cartilage toxicity on short-term follow-up."2.68Double-blind, randomized clinical trial for safety and efficacy of norfloxacin for shigellosis in children. ( Bhattacharya, K; Bhattacharya, MK; Das, KP; Deb, A; Deb, M; Dutta, D; Dutta, S; Koley, H; Nair, GB, 1997)
"In the treatment of culture-positive shigellosis cases, the responses to therapy with both drugs were similar, except that the duration of fever, anorexia, and abdominal pain were less in those who received norfloxacin."2.67Randomized clinical trial of norfloxacin for shigellosis. ( Bhattacharya, MK; Bhattacharya, SK; Dutta, P; Moitra, A; Pal, SC; Rasaily, R; Sen, D, 1991)
"When 55 patients with shigellosis (26 treated with TMP-SMX, 29 treated with norfloxacin) whose bacterial isolates were susceptible to the antibiotic given were compared by treatment group, no significant differences were seen in days of illness (mean, 2."2.66Comparison of single-dose treatment with norfloxacin and standard 5-day treatment with trimethoprim-sulfamethoxazole for acute shigellosis in adults. ( Berry, SJ; Gotuzzo, E; Guzman, M; Leon-Barua, R; Maguiña, C; Oberhelman, RA; Ruiz, R; Sack, RB; Yi, A, 1989)
" Pharmacokinetic parameters for these dosage groups were as follows: Tmax values were 3."1.28[Pharmacokinetics and clinical studies of norfloxacin in the pediatric field]. ( Aramaki, M; Kawakami, A; Koga, T; Motohiro, T; Oda, K; Oki, S; Sasaki, H; Shimada, Y; Tsumura, N; Yoshinaga, Y, 1990)
"Norfloxacin is a promising drug and is more effective than nalidixic acid in the treatment of multiresistant shigellosis."1.27Comparison of norfloxacin and nalidixic acid for treatment of dysentery caused by Shigella dysenteriae type 1 in adults. ( Habiyaremye, I; Lemmens, P; Ott, D; Rogerie, F; Vandepitte, J; Verbist, L, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's10 (71.43)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bassily, S1
Hyams, KC1
el-Masry, NA1
Farid, Z1
Cross, E1
Bourgeois, AL1
Ayad, E1
Hibbs, RG1
Bhattacharya, K1
Bhattacharya, MK3
Dutta, D2
Dutta, S1
Deb, M1
Deb, A1
Das, KP1
Koley, H1
Nair, GB2
Rataboli, PV1
D'Souza, RS1
Dhume, VG1
Moolasart, P1
Eampokalap, B1
Ratanasrithong, M1
Sen, D2
Paul, M1
Debnath, A1
Nag, A1
Dutta, P2
Pal, SC2
Bhattacharya, SK2
Rasaily, R1
Moitra, A1
Zhang, YY1
Zhun, BY1
Jiang, SC2
Wang, XF1
Wei, YL1
Motohiro, T1
Yoshinaga, Y1
Tsumura, N1
Oki, S1
Sasaki, H1
Aramaki, M1
Oda, K1
Kawakami, A1
Koga, T1
Shimada, Y1
Minamitani, M1
Hachimori, K1
Kaneda, K1
Gotuzzo, E1
Oberhelman, RA1
Maguiña, C1
Berry, SJ1
Yi, A1
Guzman, M1
Ruiz, R1
Leon-Barua, R1
Sack, RB1
Aoki, T2
Shimizu, N2
Tomizawa, I2
Takizawa, Y2
Matsubara, Y2
Seo, T2
Sagara, H2
Tagawa, K2
Masuda, G2
Negishi, M2
Rogerie, F1
Ott, D1
Vandepitte, J1
Verbist, L1
Lemmens, P1
Habiyaremye, I1

Trials

8 trials available for norfloxacin and Dysentery, Bacillary

ArticleYear
Short-course norfloxacin and trimethoprim-sulfamethoxazole treatment of shigellosis and salmonellosis in Egypt.
    The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:2

    Topics: Adult; Aged; Developing Countries; Diarrhea; Double-Blind Method; Drug Administration Schedule; Dyse

1994
Double-blind, randomized clinical trial for safety and efficacy of norfloxacin for shigellosis in children.
    Acta paediatrica (Oslo, Norway : 1992), 1997, Volume: 86, Issue:3

    Topics: Anti-Infective Agents; Child, Preschool; Double-Blind Method; Dysentery, Bacillary; Female; Humans;

1997
Comparison of the efficacy of ceftibuten and norfloxacin in the treatment of acute gastrointestinal infection in children.
    The Southeast Asian journal of tropical medicine and public health, 1999, Volume: 30, Issue:4

    Topics: Acute Disease; Anti-Infective Agents; Ceftibuten; Cephalosporins; Child; Child, Preschool; Diarrhea;

1999
Efficacy of norfloxacin for shigellosis: a double-blind randomised clinical trial.
    Journal of diarrhoeal diseases research, 1992, Volume: 10, Issue:3

    Topics: Adult; Double-Blind Method; Dysentery, Bacillary; Humans; Male; Nalidixic Acid; Norfloxacin; Shigell

1992
Randomized clinical trial of norfloxacin for shigellosis.
    The American journal of tropical medicine and hygiene, 1991, Volume: 45, Issue:6

    Topics: Adult; Dysentery, Bacillary; Humans; Nalidixic Acid; Norfloxacin

1991
[Clinical evaluation of enoxacin].
    Zhonghua nei ke za zhi, 1991, Volume: 30, Issue:8

    Topics: Adult; Dysentery, Bacillary; Enoxacin; Female; Gram-Negative Bacterial Infections; Humans; Male; Mid

1991
Comparison of single-dose treatment with norfloxacin and standard 5-day treatment with trimethoprim-sulfamethoxazole for acute shigellosis in adults.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:7

    Topics: Adult; Clinical Trials as Topic; Diarrhea; Drug Combinations; Dysentery, Bacillary; Feces; Humans; N

1989
[Comparison of clinical efficacy of norfloxacin (NFLX) and pipemidic acid (PPA) in the treatment of infectious enteritis by a double-blind method. The Japan Research Committee of Norfloxacin Research Group Enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1987, Volume: 61, Issue:7

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Dysentery,

1987

Other Studies

6 other studies available for norfloxacin and Dysentery, Bacillary

ArticleYear
An unusual hallucination with norfloxacin.
    The Journal of the Association of Physicians of India, 1996, Volume: 44, Issue:7

    Topics: Acute Disease; Adolescent; Anti-Infective Agents; Dysentery, Bacillary; Female; Hallucinations; Huma

1996
[Effect of fluoroquinolones made in China in the treatment of acute bacillary dysentery. A report of 212 cases].
    Zhonghua nei ke za zhi, 1990, Volume: 29, Issue:8

    Topics: Acute Disease; Dysentery, Bacillary; Enoxacin; Humans; Microbial Sensitivity Tests; Norfloxacin; Shi

1990
[Pharmacokinetics and clinical studies of norfloxacin in the pediatric field].
    The Japanese journal of antibiotics, 1990, Volume: 43, Issue:5

    Topics: Age Factors; Child; Drug Evaluation; Drug Resistance, Microbial; Dysentery, Bacillary; Female; Human

1990
[Clinical study on norfloxacin in pediatrics].
    The Japanese journal of antibiotics, 1990, Volume: 43, Issue:5

    Topics: Adolescent; Age Factors; Campylobacter Infections; Child; Child, Preschool; Drug Evaluation; Dysente

1990
[Clinical study of AM-715 on acute infectious enteritis. The Japan Research Committee of AM-715, Research Group for Acute Infectious Enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1986, Volume: 60, Issue:5

    Topics: Acute Disease; Administration, Oral; Campylobacter Infections; Drug Administration Schedule; Dysente

1986
Comparison of norfloxacin and nalidixic acid for treatment of dysentery caused by Shigella dysenteriae type 1 in adults.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Dysentery, Bacillary; Female; Humans; Male; Middle Aged; Nalidixic Acid; Norfloxa

1986