norfloxacin has been researched along with Diabetes Mellitus, Type 2 in 2 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with norfloxacin and ampicillin for 2 weeks reduced the cecal bacterial DNA below the level of detection in ob/ob, diet-induced obese and insulin resistance (DIO) mice, and significantly improved fasting glycemia and oral glucose tolerance of the treated animals." | 2.44 | Gut decontamination with norfloxacin and ampicillin enhances insulin sensitivity in mice. ( Blancher, F; Chou, CJ; Membrez, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chou, CJ | 2 |
| Membrez, M | 2 |
| Blancher, F | 2 |
| Jaquet, M | 1 |
| Bibiloni, R | 1 |
| Cani, PD | 1 |
| Burcelin, RG | 1 |
| Corthesy, I | 1 |
| Macé, K | 1 |
1 review available for norfloxacin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Gut decontamination with norfloxacin and ampicillin enhances insulin sensitivity in mice.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Blood Glucose; Cecum; Diabetes Mellitus, Type 2; Glucose | 2008 |
1 other study available for norfloxacin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Bacteroides; Bifidobacterium; Diabetes Mellitus, Type 2; | 2008 |