norfloxacin has been researched along with Cystitis in 27 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and safety of a 5-day course of treatment with the new oral penem agent ritipenem acoxil (500 mg three times daily) or with norfloxacin (200 mg twice daily) were assessed in a double-blind study of women with uncomplicated cystitis." | 9.08 | Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin. Swedish Urinary Tract Infection Study Group. ( , 1995) |
| "The efficacy and safety of rufloxacin (400 mg, single dose) were compared to those of norfloxacin (400 mg twice a day for 3 days) for the treatment of women with uncomplicated cystitis." | 9.08 | Single-dose rufloxacin versus 3-day norfloxacin treatment of uncomplicated cystitis: clinical evaluation and pharmacodynamic considerations. ( Aguilar, L; Caffaratti, J; Dal-Ré, R; Dalet, F; Del Río, G, 1996) |
| "In a double-blind four-block randomized trial the efficacy and tolerance of a single dose of pefloxacin 800 mg was compared with a five day treatment with norfloxacin 400 mg twice daily in the treatment of uncomplicated urinary tract infections in general practice." | 9.06 | Single-dose pefloxacin versus five-days treatment with norfloxacin in uncomplicated cystitis in women. ( de Melker, RA; Touw-Otten, FW; van Balen, FA, 1990) |
| "Eighty-two evaluable patients suffering from UTI were randomly treated with parenteral Aztreonam (1 g OD in cystitis and 1 g BID in pyelonephritis) or oral Norfloxacin (400 mg BID)." | 9.06 | [Aztreonam vs norfloxacin: a comparative study of the treatment of urinary tract infections in ambulatory and hospitalized patients]. ( De Rose, AF; Germinale, F; Puppo, P, 1989) |
| "To objectively evaluate the efficacy, safety and utility of lomefloxacin (NY-198), a new quinolone antibacterial agent, in the treatment of acute uncomplicated cystitis, a comparative double blind trial was performed using norfloxacin (NFLX) as the control drug." | 9.06 | [A comparative study on lomefloxacin and norfloxacin in the treatment of acute uncomplicated cystitis]. ( Amano, M; Arakawa, S; Fujita, Y; Ishigami, J; Kamidono, S; Kanemasa, Y; Kumon, H; Ohmori, H; Suzuki, K; Tanaka, H, 1989) |
| "A 65-year-old woman developed haemorrhagic diathesis due to a profound thrombocytopenia (thrombocyte count: 1 x 10(9)/l) within one week after a 10-day course of norfloxacin (2 x 400 mg/day), prescribed for cystitis." | 7.69 | [Immune thrombocytopenia attributed to norfloxacin]. ( Vlasveld, LT; Wensing, JW, 1997) |
| "Oral doses of norfloxacin (80 mg/kg of body weight per day) and ciprofloxacin (25 and 80 mg/kg/day) and intramuscular doses of teicoplanin (5 mg/kg/day), all administered once a day for 10 days, were evaluated as a means of preventing encrusted cystitis caused by Corynebacterium group D2." | 7.68 | Treatment of encrusted cystitis caused by Corynebacterium group D2 with norfloxacin, ciprofloxacin, and teicoplanin in an experimental model in rats. ( Avilés, P; Castilla, C; Rodriguez-Tudela, JL; Soriano, F, 1991) |
| "The therapeutic effectiveness of a single oral dose (60 and 200 mg/kg body weight) of fosfomycin trometamol (FT), norfloxacin, trimethoprim sulfamethoxazole (Bactrim) and pipemidic acid against experimental cystitis in the rat were compared." | 7.67 | Treatment of experimental cystitis in the rat with a single dose of fosfomycin trometamol. ( Dubini, F; Riviera, L, 1988) |
| "25 women with acute uncomplicated cystitis were treated with a single dose of 800 mg norfloxacin orally." | 7.67 | [Single-dose treatment of acute cystitis with norfloxacin. 1st report]. ( Bischoff, H; Bischoff, W; Schniepp, C, 1985) |
| "The clinical effectiveness and safety of norfloxacin were evaluated in 34 patients with urinary tract infections." | 7.67 | [Clinical studies of norfloxacin in urinary tract infections]. ( Kurita, T; Matsuura, T, 1985) |
| "The efficacy and safety of a 5-day course of treatment with the new oral penem agent ritipenem acoxil (500 mg three times daily) or with norfloxacin (200 mg twice daily) were assessed in a double-blind study of women with uncomplicated cystitis." | 5.08 | Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin. Swedish Urinary Tract Infection Study Group. ( , 1995) |
| "The efficacy and safety of rufloxacin (400 mg, single dose) were compared to those of norfloxacin (400 mg twice a day for 3 days) for the treatment of women with uncomplicated cystitis." | 5.08 | Single-dose rufloxacin versus 3-day norfloxacin treatment of uncomplicated cystitis: clinical evaluation and pharmacodynamic considerations. ( Aguilar, L; Caffaratti, J; Dal-Ré, R; Dalet, F; Del Río, G, 1996) |
| "In a double-blind four-block randomized trial the efficacy and tolerance of a single dose of pefloxacin 800 mg was compared with a five day treatment with norfloxacin 400 mg twice daily in the treatment of uncomplicated urinary tract infections in general practice." | 5.06 | Single-dose pefloxacin versus five-days treatment with norfloxacin in uncomplicated cystitis in women. ( de Melker, RA; Touw-Otten, FW; van Balen, FA, 1990) |
| "The aim of this study was to carry out a small-scale bacteriological comparison between a standard therapy with norfloxacin 400 mg twice daily, and fosfomycin trometamol (3 g) in single dose in uncomplicated urinary tract infections (UTI) in women." | 5.06 | Single dose fosfomycin trometamol versus multiple dose norfloxacin over three days for uncomplicated UTI in general practice. ( Reynaert, J; Van Eyck, D; Vandepitte, J, 1990) |
| "Eighty-two evaluable patients suffering from UTI were randomly treated with parenteral Aztreonam (1 g OD in cystitis and 1 g BID in pyelonephritis) or oral Norfloxacin (400 mg BID)." | 5.06 | [Aztreonam vs norfloxacin: a comparative study of the treatment of urinary tract infections in ambulatory and hospitalized patients]. ( De Rose, AF; Germinale, F; Puppo, P, 1989) |
| "To objectively evaluate the efficacy, safety and utility of lomefloxacin (NY-198), a new quinolone antibacterial agent, in the treatment of acute uncomplicated cystitis, a comparative double blind trial was performed using norfloxacin (NFLX) as the control drug." | 5.06 | [A comparative study on lomefloxacin and norfloxacin in the treatment of acute uncomplicated cystitis]. ( Amano, M; Arakawa, S; Fujita, Y; Ishigami, J; Kamidono, S; Kanemasa, Y; Kumon, H; Ohmori, H; Suzuki, K; Tanaka, H, 1989) |
| "A 65-year-old woman developed haemorrhagic diathesis due to a profound thrombocytopenia (thrombocyte count: 1 x 10(9)/l) within one week after a 10-day course of norfloxacin (2 x 400 mg/day), prescribed for cystitis." | 3.69 | [Immune thrombocytopenia attributed to norfloxacin]. ( Vlasveld, LT; Wensing, JW, 1997) |
| "Oral doses of norfloxacin (80 mg/kg of body weight per day) and ciprofloxacin (25 and 80 mg/kg/day) and intramuscular doses of teicoplanin (5 mg/kg/day), all administered once a day for 10 days, were evaluated as a means of preventing encrusted cystitis caused by Corynebacterium group D2." | 3.68 | Treatment of encrusted cystitis caused by Corynebacterium group D2 with norfloxacin, ciprofloxacin, and teicoplanin in an experimental model in rats. ( Avilés, P; Castilla, C; Rodriguez-Tudela, JL; Soriano, F, 1991) |
| "The effect of a single day treatment with 600 mg norfloxacin 600 mg ofloxacin or 1,920 mg trimethoprim-sulfamethoxazol was determined on 114 patients with acute cystitis." | 3.67 | [Single day treatment in acute cystitis]. ( Kawaguchi, K; Yamaguchi, K, 1988) |
| "The therapeutic effectiveness of a single oral dose (60 and 200 mg/kg body weight) of fosfomycin trometamol (FT), norfloxacin, trimethoprim sulfamethoxazole (Bactrim) and pipemidic acid against experimental cystitis in the rat were compared." | 3.67 | Treatment of experimental cystitis in the rat with a single dose of fosfomycin trometamol. ( Dubini, F; Riviera, L, 1988) |
| "The clinical effectiveness and safety of norfloxacin were evaluated in 34 patients with urinary tract infections." | 3.67 | [Clinical studies of norfloxacin in urinary tract infections]. ( Kurita, T; Matsuura, T, 1985) |
| "Uncomplicated acute cystitis is one of the most common bacterial infections in adults." | 2.43 | Quinolones for uncomplicated acute cystitis in women. ( Andreeva, I; Rafalsky, V; Rjabkova, E, 2006) |
| "To explore the urine bactericidal activity of co-amoxiclav and norfloxacin against Escherichia coli in an in vitro pharmacodynamic model simulating the human urinary concentrations observed after administration of a single oral dose of 2000/125 mg sustained-release co-amoxiclav and 400 mg norfloxacin." | 1.33 | Urine bactericidal activity against resistant Escherichia coli in an in vitro pharmacodynamic model simulating urine concentrations obtained after 2000/125 mg sustained-release co-amoxiclav and 400 mg norfloxacin administration. ( Aguilar, L; Alou, L; Cafini, F; Giménez, MJ; Prieto, J; Relaño, MT; Sevillano, D; Valero, E, 2006) |
| "Norfloxacin was the most active of the seven compounds tested and was the only one to which resistance did not emerge at the concentrations tested." | 1.27 | The assessment of antimicrobial activity in an in-vitro model of the treatment of bacterial cystitis. ( Greenwood, D, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (55.56) | 18.7374 |
| 1990's | 8 (29.63) | 18.2507 |
| 2000's | 3 (11.11) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gauld, NJ | 1 |
| Zeng, IS | 1 |
| Ikram, RB | 1 |
| Thomas, MG | 1 |
| Buetow, SA | 1 |
| Alou, L | 1 |
| Aguilar, L | 2 |
| Sevillano, D | 1 |
| Giménez, MJ | 1 |
| Cafini, F | 1 |
| Valero, E | 1 |
| Relaño, MT | 1 |
| Prieto, J | 1 |
| Rafalsky, V | 1 |
| Andreeva, I | 1 |
| Rjabkova, E | 1 |
| Greenwood, D | 2 |
| Guibert, J | 2 |
| Mazeman, E | 1 |
| Colau, JC | 1 |
| Delavault, P | 1 |
| Del Río, G | 1 |
| Dalet, F | 1 |
| Caffaratti, J | 1 |
| Dal-Ré, R | 1 |
| Herman, H | 1 |
| Capron, MH | 1 |
| Wensing, JW | 1 |
| Vlasveld, LT | 1 |
| Soriano, F | 1 |
| Rodriguez-Tudela, JL | 1 |
| Castilla, C | 1 |
| Avilés, P | 1 |
| van Balen, FA | 1 |
| Touw-Otten, FW | 1 |
| de Melker, RA | 1 |
| Reynaert, J | 1 |
| Van Eyck, D | 1 |
| Vandepitte, J | 1 |
| Kanematsu, M | 1 |
| Puppo, P | 1 |
| Germinale, F | 1 |
| De Rose, AF | 1 |
| Ohmori, H | 1 |
| Kumon, H | 1 |
| Suzuki, K | 1 |
| Kamidono, S | 1 |
| Arakawa, S | 1 |
| Ishigami, J | 1 |
| Tanaka, H | 1 |
| Amano, M | 1 |
| Fujita, Y | 1 |
| Kanemasa, Y | 1 |
| Yamaguchi, K | 1 |
| Kawaguchi, K | 1 |
| Gargallo, D | 1 |
| Moros, M | 1 |
| Coll, R | 1 |
| Esteve, M | 1 |
| Parés, J | 1 |
| Xicota, MA | 1 |
| Guinea, J | 1 |
| Bischoff, W | 2 |
| Dubini, F | 3 |
| Riviera, L | 3 |
| Visconti, A | 1 |
| Yamamoto, M | 1 |
| Nagai, T | 1 |
| Takaba, H | 1 |
| Hashimoto, J | 1 |
| Miyake, K | 1 |
| Gallego Gómez, J | 1 |
| Llopis Mínguez, B | 1 |
| Boronat Tormo, F | 1 |
| Martínez García, R | 1 |
| Oliver Amorós, F | 1 |
| Gobernado Serrano, M | 1 |
| Jiménez Cruz, JF | 1 |
| Bischoff, H | 1 |
| Schniepp, C | 1 |
| Fukuoka, H | 1 |
| Goto, A | 1 |
| Sasaki, S | 1 |
| Matsuura, T | 1 |
| Kurita, T | 1 |
1 review available for norfloxacin and Cystitis
| Article | Year |
|---|---|
Quinolones for uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolo | 2006 |
9 trials available for norfloxacin and Cystitis
| Article | Year |
|---|---|
Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin. Swedish Urinary Tract Infection Study Group.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteriuria; Cystitis; Data Interpretation, Statisti | 1995 |
[Acute cystitis in women over 50 years of age. Efficacy of pefloxacin with single dose and norfloxacin for 10 days].
Topics: Acute Disease; Administration, Oral; Aged; Cystitis; Drug Evaluation; Drug Therapy, Combination; Fem | 1993 |
Single-dose rufloxacin versus 3-day norfloxacin treatment of uncomplicated cystitis: clinical evaluation and pharmacodynamic considerations.
Topics: Adult; Anti-Infective Agents; Cystitis; Escherichia coli Infections; Female; Fluoroquinolones; Human | 1996 |
[Treatment of uncomplicated recurrent cystitis in women: lomefloxacin versus norfloxacin].
Topics: Adult; Anti-Infective Agents; Cystitis; Drug Administration Schedule; Female; Fluoroquinolones; Huma | 1997 |
Single-dose pefloxacin versus five-days treatment with norfloxacin in uncomplicated cystitis in women.
Topics: Adult; Cystitis; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Human | 1990 |
Single dose fosfomycin trometamol versus multiple dose norfloxacin over three days for uncomplicated UTI in general practice.
Topics: Adolescent; Adult; Aged; Cystitis; Drug Administration Schedule; Escherichia coli; Female; Fosfomyci | 1990 |
[Aztreonam vs norfloxacin: a comparative study of the treatment of urinary tract infections in ambulatory and hospitalized patients].
Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Aztreonam; Clinical Trials as Topic; Cystitis; F | 1989 |
[A comparative study on lomefloxacin and norfloxacin in the treatment of acute uncomplicated cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bacteria; Child; Clinical Trials as T | 1989 |
[Norfloxacin versus pipemidic acid in acute cystitis].
Topics: Acute Disease; Cystitis; Female; Humans; Nicotinic Acids; Norfloxacin; Pipemidic Acid | 1987 |
17 other studies available for norfloxacin and Cystitis
| Article | Year |
|---|---|
Treatment of uncomplicated cystitis: analysis of prescribing in New Zealand.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Cystitis; Dose-Response Relationship, Drug; Drug Pre | 2016 |
Urine bactericidal activity against resistant Escherichia coli in an in vitro pharmacodynamic model simulating urine concentrations obtained after 2000/125 mg sustained-release co-amoxiclav and 400 mg norfloxacin administration.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cystitis; Delayed-Action Prepa | 2006 |
The assessment of antimicrobial activity in an in-vitro model of the treatment of bacterial cystitis.
Topics: Anti-Infective Agents, Urinary; Cystitis; Drug Resistance, Microbial; Escherichia coli; Nalidixic Ac | 1984 |
[Immune thrombocytopenia attributed to norfloxacin].
Topics: Aged; Anti-Infective Agents; Autoimmune Diseases; Cystitis; Female; Hemorrhagic Disorders; Humans; N | 1997 |
Effectiveness of 3 vs. 7 day therapy cited.
Topics: Anti-Infective Agents; Ciprofloxacin; Cystitis; Drug Administration Schedule; Female; Humans; Norflo | 2001 |
Treatment of encrusted cystitis caused by Corynebacterium group D2 with norfloxacin, ciprofloxacin, and teicoplanin in an experimental model in rats.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium Infections; Cystitis; Female; Glycope | 1991 |
Studies on the emergence of resistance to lomefloxacin in vitro.
Topics: Anti-Infective Agents; Ciprofloxacin; Cystitis; Drug Resistance, Microbial; Escherichia coli; Fluoro | 1989 |
[Single day treatment in acute cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Cystitis; | 1988 |
Activity of E-3846, a new fluoroquinolone, in vitro and in experimental cystitis and pyelonephritis in rats.
Topics: Animals; Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacteria; Chemical Phenomena; Chemis | 1988 |
[Norfloxacin treatment of acute cystitis in the female and bacterial prostatitis].
Topics: Adult; Anti-Infective Agents, Urinary; Bacterial Infections; Cystitis; Female; Humans; Male; Microbi | 1985 |
Treatment of experimental cystitis in the rat with a single dose of fosfomycin trometamol.
Topics: Administration, Oral; Animals; Bacterial Infections; Cystitis; Drug Combinations; Fosfomycin; Norflo | 1988 |
Antibacterial activity in human urine of fosfomycin trometamol in an in vitro model of the urinary bladder.
Topics: Administration, Oral; Adolescent; Adult; Bacteria; Cystitis; Drug Combinations; Fosfomycin; Humans; | 1988 |
[Experimental cystitis in the rat and the therapeutic effect of a single dose of fosfomycin trometamol].
Topics: Animals; Cystitis; Drug Combinations; Drug Evaluation, Preclinical; Escherichia coli Infections; Fos | 1987 |
Comparison of enoxacin and norfloxacin in patients with cystitis.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacteria; Cystitis; Drug Resistance, Microb | 1987 |
[Single-dose treatment of acute cystitis with norfloxacin. 1st report].
Topics: Adult; Cystitis; Drug Administration Schedule; Escherichia coli; Female; Humans; Norfloxacin; Pseudo | 1985 |
[Clinical experience of norfloxacin (Baccidal) in the urological field].
Topics: Adult; Aged; Bacteria; Cystitis; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Middle | 1985 |
[Clinical studies of norfloxacin in urinary tract infections].
Topics: Adult; Aged; Cystitis; Drug Evaluation; Drug Resistance, Microbial; Enterobacteriaceae; Female; Huma | 1985 |