Page last updated: 2024-11-01

norfloxacin and Cystic Fibrosis

norfloxacin has been researched along with Cystic Fibrosis in 4 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, WJ1
Goeckeler-Fried, JL1
Havasi, V1
Chiang, A1
Rowe, SM1
Plyler, ZE1
Hong, JS1
Mazur, M1
Piazza, GA1
Keeton, AB1
White, EL1
Rasmussen, L1
Weissman, AM1
Denny, RA1
Brodsky, JL1
Sorscher, EJ1
James, CE1
Fothergill, JL1
Hall, AJ1
Cottell, J1
Brockhurst, MA1
Winstanley, C1
Doershuk, CF1
Stern, RC1
Jalal, S1
Ciofu, O1
Hoiby, N1
Gotoh, N1
Wretlind, B1

Other Studies

4 other studies available for norfloxacin and Cystic Fibrosis

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu

2016
Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa.
    BMC microbiology, 2012, 09-21, Volume: 12

    Topics: Adult; Animals; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Fimbriae, Bacterial

2012
Spontaneous bacterial peritonitis in cystic fibrosis.
    Gut, 1994, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Bacterial Infections; Cystic Fibrosis; Female; Humans; Liver Cirrhosis; Male; Nor

1994
Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3

    Topics: Adult; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Ciprofloxacin;

2000