norfloxacin has been researched along with Cirrhoses, Experimental Liver in 6 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To assess the effect of hemorrhagic shock (HS) on the incidence of BT and if selective intestinal decontamination (SID) reduces this incidence, we studied six groups of Sprague-Dawley rats: ascitic rats, ascitic rats exposed to HS with and without previous norfloxacin prophylaxis, healthy rats, and healthy shocked rats with and without previous norfloxacin prophylaxis." | 7.69 | Selective intestinal decontamination with norfloxacin reduces bacterial translocation in ascitic cirrhotic rats exposed to hemorrhagic shock. ( Arnal, J; Ausina, V; Bartolí, R; Cabré, E; Gassull, MA; Llovet, JM; Ojanguren, I; Pérez, J; Planas, R; Viñado, B, 1996) |
| "Norfloxacin administration is useful in preventing bacterial infections in cirrhosis but associated to the generation of resistant species." | 3.88 | Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis. ( Bellot, P; Francés, R; García, I; Gimenez, P; Gómez-Hurtado, I; González-Navajas, JM; Guarner, F; Manichanh, C; Ramos, JM; Such, J; Zapater, P, 2018) |
| " We used antibiotic (norfloxacin) and different probiotic treatments to change the status of gut flora in the cirrhotic rats and evaluated BT, liver function, and endotoxemia in the different models." | 3.76 | Intestinal flora imbalance results in altered bacterial translocation and liver function in rats with experimental cirrhosis. ( Chen, L; Chen, S; Chen, Y; Deng, H; Gao, Z; Gu, Y; Zhang, G; Zhang, W, 2010) |
| " To assess the effect of hemorrhagic shock (HS) on the incidence of BT and if selective intestinal decontamination (SID) reduces this incidence, we studied six groups of Sprague-Dawley rats: ascitic rats, ascitic rats exposed to HS with and without previous norfloxacin prophylaxis, healthy rats, and healthy shocked rats with and without previous norfloxacin prophylaxis." | 3.69 | Selective intestinal decontamination with norfloxacin reduces bacterial translocation in ascitic cirrhotic rats exposed to hemorrhagic shock. ( Arnal, J; Ausina, V; Bartolí, R; Cabré, E; Gassull, MA; Llovet, JM; Ojanguren, I; Pérez, J; Planas, R; Viñado, B, 1996) |
| "Norfloxacin is a gram-negative bactericidal drug able to maintain low endotoxin levels and stimulate IL-10 production." | 1.40 | Role of interleukin 10 in norfloxacin prevention of luminal free endotoxin translocation in mice with cirrhosis. ( Francés, R; Giménez, P; Gómez-Hurtado, I; González-Navajas, JM; Moratalla, A; Moya-Pérez, Á; Peiró, G; Sanz, Y; Such, J; Zapater, P, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gómez-Hurtado, I | 2 |
| Gimenez, P | 2 |
| García, I | 1 |
| Zapater, P | 2 |
| Francés, R | 2 |
| González-Navajas, JM | 2 |
| Manichanh, C | 1 |
| Ramos, JM | 1 |
| Bellot, P | 1 |
| Guarner, F | 1 |
| Such, J | 2 |
| Moratalla, A | 1 |
| Moya-Pérez, Á | 1 |
| Peiró, G | 1 |
| Sanz, Y | 1 |
| Gustot, T | 1 |
| Zhang, W | 1 |
| Gu, Y | 1 |
| Chen, Y | 1 |
| Deng, H | 1 |
| Chen, L | 1 |
| Chen, S | 1 |
| Zhang, G | 1 |
| Gao, Z | 1 |
| Runyon, BA | 1 |
| Borzio, M | 1 |
| Young, S | 1 |
| Squier, SU | 1 |
| Guarner, C | 1 |
| Runyon, MA | 1 |
| Llovet, JM | 1 |
| Bartolí, R | 1 |
| Planas, R | 1 |
| Viñado, B | 1 |
| Pérez, J | 1 |
| Cabré, E | 1 |
| Arnal, J | 1 |
| Ojanguren, I | 1 |
| Ausina, V | 1 |
| Gassull, MA | 1 |
6 other studies available for norfloxacin and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Bacterial Translocation; Carbon Tetrachloride; | 2018 |
Role of interleukin 10 in norfloxacin prevention of luminal free endotoxin translocation in mice with cirrhosis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Translocation; Endotoxins; Escherichia coli; Inflammation; | 2014 |
New findings about an 'old' drug: immunomodulatory effects of norfloxacin in cirrhosis.
Topics: Animals; Endotoxins; Escherichia coli; Interleukin-10; Intestines; Klebsiella pneumoniae; Liver Cirr | 2014 |
Intestinal flora imbalance results in altered bacterial translocation and liver function in rats with experimental cirrhosis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Translocation; Bifidobacterium; Carbon Tetrachloride; Endo | 2010 |
Effect of selective bowel decontamination with norfloxacin on spontaneous bacterial peritonitis, translocation, and survival in an animal model of cirrhosis.
Topics: Administration, Oral; Animals; Carbon Tetrachloride Poisoning; Enterobacteriaceae; Enterobacteriacea | 1995 |
Selective intestinal decontamination with norfloxacin reduces bacterial translocation in ascitic cirrhotic rats exposed to hemorrhagic shock.
Topics: Animals; Anti-Infective Agents; Bacterial Physiological Phenomena; Intestines; Liver Cirrhosis, Expe | 1996 |