Page last updated: 2024-11-01

norfloxacin and Chronic Illness

norfloxacin has been researched along with Chronic Illness in 16 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Research Excerpts

ExcerptRelevanceReference
"Studies on a combination therapy of fosfomycin (FOM) and norfloxacin (NFLX) against chronic otitis media were performed, and the following results were obtained."7.70[Combination effect of fosfomycin otic solution and norfloxacin against chronic otitis media]. ( Uno, Y, 1999)
"We treated 15 men who had chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin with 400 mg."7.68The efficacy of norfloxacin in the treatment of chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin. ( Darras, FS; Schaeffer, AJ, 1990)
"The clinical efficacy of norfloxacin (NFLX) was evaluated in 74 patients having chronic prostatitis with the subjective symptoms suggesting the inflammations of prostate and more than five white bloodcells (WBCs)/hpf in their prostatic secretions (EPS)."7.67[The therapeutic effect of norfloxacin on chronic prostatitis]. ( Gouro, T; Henmi, I; Igawa, K; Kadono, M; Kumamoto, Y; Maekwa, S; Oguma, K; Okayama, S; Sakai, S; Tsukamoto, T, 1987)
"Forty-three patients admitted to hospital with acute purulent exacerbations of chronic bronchitis were treated with 400 mg pefloxacin twice daily for ten days."7.67Pefloxacin in acute exacerbations of chronic bronchitis. ( Davies, BI; Maesen, FP; Teengs, JP, 1985)
"Ten patients with bacterial overgrowth-related diarrhea underwent the following five 7-day treatment periods: untreated (control period), then placebo, and subsequently, in random order and blinded fashion, norfloxacin (800 mg/day), amoxicillin-clavulanic acid (1500 mg/day), and Saccharomyces boulardii (1500 mg/day)."5.09Antibiotic efficacy in small intestinal bacterial overgrowth-related chronic diarrhea: a crossover, randomized trial. ( Attar, A; Bouhnik, Y; FlouriƩ, B; Franchisseur, C; Rambaud, JC; Ruszniewski, P, 1999)
"Studies on a combination therapy of fosfomycin (FOM) and norfloxacin (NFLX) against chronic otitis media were performed, and the following results were obtained."3.70[Combination effect of fosfomycin otic solution and norfloxacin against chronic otitis media]. ( Uno, Y, 1999)
"We treated 15 men who had chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin with 400 mg."3.68The efficacy of norfloxacin in the treatment of chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin. ( Darras, FS; Schaeffer, AJ, 1990)
"The clinical efficacy of norfloxacin (NFLX) was evaluated in 74 patients having chronic prostatitis with the subjective symptoms suggesting the inflammations of prostate and more than five white bloodcells (WBCs)/hpf in their prostatic secretions (EPS)."3.67[The therapeutic effect of norfloxacin on chronic prostatitis]. ( Gouro, T; Henmi, I; Igawa, K; Kadono, M; Kumamoto, Y; Maekwa, S; Oguma, K; Okayama, S; Sakai, S; Tsukamoto, T, 1987)
"Forty-three patients admitted to hospital with acute purulent exacerbations of chronic bronchitis were treated with 400 mg pefloxacin twice daily for ten days."3.67Pefloxacin in acute exacerbations of chronic bronchitis. ( Davies, BI; Maesen, FP; Teengs, JP, 1985)
" We employed a rat model of chronic bacterial prostatitis to investigate any pharmacokinetic differences that may exist between uninflamed and inflamed prostate glands."1.29Antibiotic pharmacokinetics in the inflamed prostate. ( Ceri, H; Clark, J; Downey, J; Nickel, JC; Olson, M, 1995)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's8 (50.00)18.2507
2000's1 (6.25)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Molla, R1
Tiruneh, M1
Abebe, W1
Moges, F1
Mwachari, CW1
Meier, AS1
Muyodi, J1
Gatei, W1
Waiyaki, P1
Cohen, CR1
Peppas, T1
Petrikkos, G1
Deliganni, V1
Zoumboulis, P1
Koulentianos, E1
Giamarellou, H1
Nickel, JC1
Downey, J1
Clark, J1
Ceri, H1
Olson, M1
Levadoux, M1
Carli, P1
Gadea, JF1
De Mauleon De Bruyere, P1
Perre, C1
Sumano, LH1
Ocampo, CL1
Brumbaugh, GW1
Lizarraga, RE1
Uno, Y1
Attar, A1
FlouriƩ, B1
Rambaud, JC1
Franchisseur, C1
Ruszniewski, P1
Bouhnik, Y1
Schaeffer, AJ1
Darras, FS1
Morikawa, M1
Tokunaka, S1
Yachiku, S1
Yamauchi, K1
Wakabayashi, A1
Inagaki, N1
Nishihara, M1
Yamaguchi, S1
Majima, Y1
Hirata, K1
Takeuchi, K1
Hattori, M1
Sakakura, Y1
Mertens, JC1
Dekker, W1
Ligtvoet, EE1
Blok, P1
Davies, BI2
Maesen, FP2
Teengs, JP2
Baur, C1
Comhaire, FH1
Kumamoto, Y1
Tsukamoto, T1
Sakai, S1
Gouro, T1
Maekwa, S1
Oguma, K1
Henmi, I1
Igawa, K1
Kadono, M1
Okayama, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing[NCT01324895]944 participants (Actual)Observational2010-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for norfloxacin and Chronic Illness

ArticleYear
Effectiveness of two fluoroquinolones for the treatment of chronic respiratory disease outbreak in broilers.
    British poultry science, 1998, Volume: 39, Issue:1

    Topics: Animals; Anti-Infective Agents; Body Weight; Chickens; Chronic Disease; Disease Outbreaks; Enrofloxa

1998
Antibiotic efficacy in small intestinal bacterial overgrowth-related chronic diarrhea: a crossover, randomized trial.
    Gastroenterology, 1999, Volume: 117, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria;

1999

Other Studies

14 other studies available for norfloxacin and Chronic Illness

ArticleYear
Bacterial profile and antimicrobial susceptibility patterns in chronic suppurative otitis media at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.
    BMC research notes, 2019, Jul-15, Volume: 12, Issue:1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chronic Disease; Ciprofloxacin; Clarithromyci

2019
Chronic diarrhoea in HIV-1-infected adults in Nairobi, Kenya: evaluation of risk factors and the WHO treatment algorithm.
    AIDS (London, England), 2003, Sep-26, Volume: 17, Issue:14

    Topics: Adult; Algorithms; Anti-Infective Agents; Chronic Disease; Cohort Studies; Diarrhea; Drug Therapy, C

2003
Efficacy of long-term therapy with norfloxacin in chronic bacterial prostatitis.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Humans; Male; Mi

1989
Antibiotic pharmacokinetics in the inflamed prostate.
    The Journal of urology, 1995, Volume: 153, Issue:2

    Topics: Animals; Bacterial Infections; Chronic Disease; Male; Norfloxacin; Prostatitis; Rats; Rats, Sprague-

1995
[Repeated rupture of the extensor tendons of the hand due to fluoroquinolones. Apropos of a case].
    Annales de chirurgie de la main et du membre superieur : organe officiel des societes de chirurgie de la main = Annals of hand and upper limb surgery, 1997, Volume: 16, Issue:2

    Topics: Acute Disease; Aged; Anti-Infective Agents; Blood Vessels; Chronic Disease; Female; Hand; Hemosidero

1997
[Combination effect of fosfomycin otic solution and norfloxacin against chronic otitis media].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1999, Volume: 73, Issue:4

    Topics: Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Chronic

1999
The efficacy of norfloxacin in the treatment of chronic bacterial prostatitis refractory to trimethoprim-sulfamethoxazole and/or carbenicillin.
    The Journal of urology, 1990, Volume: 144, Issue:3

    Topics: Carbenicillin; Chronic Disease; Escherichia coli Infections; Follow-Up Studies; Humans; Male; Middle

1990
[The therapeutic effect of norfloxacin on chronic prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1990, Volume: 36, Issue:10

    Topics: Adult; Aged; Bacterial Infections; Chronic Disease; Drug Evaluation; Humans; Leukocyte Count; Male;

1990
Effects of orally administered drugs on dynamic viscoelasticity of human nasal mucus.
    The American review of respiratory disease, 1990, Volume: 141, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Carbocysteine; Chronic Disease; El

1990
Treatment failure of norfloxacin against Campylobacter pylori and chronic gastritis in patients with nonulcerative dyspepsia.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:2

    Topics: Campylobacter Infections; Chronic Disease; Dyspepsia; Gastritis; Humans; Norfloxacin

1989
[New oral quinolone compounds in chronic bronchitis].
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Cipr

1986
Concentration of pefloxacine in split ejaculates of patients with chronic male accessory gland infection.
    The Journal of urology, 1987, Volume: 138, Issue:4

    Topics: Adult; Chronic Disease; Exocrine Glands; Genital Diseases, Male; Humans; Infertility, Male; Inflamma

1987
[The therapeutic effect of norfloxacin on chronic prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:3

    Topics: Adult; Aged; Chronic Disease; Drug Resistance, Microbial; Gram-Negative Bacteria; Humans; Male; Micr

1987
Pefloxacin in acute exacerbations of chronic bronchitis.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:3

    Topics: Anti-Bacterial Agents; Bacteria; Bronchitis; Chronic Disease; Female; Humans; Kinetics; Male; Microb

1985