norfloxacin has been researched along with Chemical and Drug Induced Liver Injury in 12 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Norfloxacin administration is useful in preventing bacterial infections in cirrhosis but associated to the generation of resistant species." | 3.88 | Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis. ( Bellot, P; Francés, R; García, I; Gimenez, P; Gómez-Hurtado, I; González-Navajas, JM; Guarner, F; Manichanh, C; Ramos, JM; Such, J; Zapater, P, 2018) |
| " In this study, we investigated the toxic effects of carp exposed to 0, 100 ng/L, and 1 mg/L norfloxacin (NOR) at environmental concentrations for 42 days." | 1.62 | Hepatotoxicity in carp (Cyprinus carpio) exposed to environmental levels of norfloxacin (NOR): Some latest evidences from transcriptomics analysis, biochemical parameters and histopathological changes. ( Cao, ZH; He, SW; Li, P; Li, ZH; Xing, SY; Zhang, HQ; Zhang, SQ; Zhao, XL, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Zhang, SQ | 1 |
| Li, P | 1 |
| Zhao, XL | 1 |
| He, SW | 1 |
| Xing, SY | 1 |
| Cao, ZH | 1 |
| Zhang, HQ | 1 |
| Li, ZH | 1 |
| Gómez-Hurtado, I | 1 |
| Gimenez, P | 1 |
| García, I | 1 |
| Zapater, P | 1 |
| Francés, R | 1 |
| González-Navajas, JM | 1 |
| Manichanh, C | 1 |
| Ramos, JM | 1 |
| Bellot, P | 1 |
| Guarner, F | 1 |
| Such, J | 1 |
| Elliott, TR | 1 |
| Symes, T | 1 |
| Kannourakis, G | 1 |
| Angus, P | 1 |
| Davoren, P | 1 |
| Mainstone, K | 1 |
| Romero-Gómez, M | 1 |
| Suárez García, E | 1 |
| Fernández, MC | 1 |
| Björnsson, E | 1 |
| Olsson, R | 1 |
| Remotti, H | 1 |
| Clark, DW | 1 |
| Layton, D | 1 |
| Wilton, LV | 1 |
| Pearce, GL | 1 |
| Shakir, SA | 1 |
| López-Navidad, A | 1 |
| Domingo, P | 1 |
| Cadafalch, J | 1 |
| Farrerons, J | 1 |
1 review available for norfloxacin and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
11 other studies available for norfloxacin and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Hepatotoxicity in carp (Cyprinus carpio) exposed to environmental levels of norfloxacin (NOR): Some latest evidences from transcriptomics analysis, biochemical parameters and histopathological changes.
Topics: Animals; Carps; Chemical and Drug Induced Liver Injury; Liver; Norfloxacin; Transcriptome; Water Pol | 2021 |
Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Bacterial Translocation; Carbon Tetrachloride; | 2018 |
Resolution of norfloxacin-induced acute liver failure after N-acetylcysteine therapy: further support for the use of NAC in drug-induced ALF?
Topics: Acetylcysteine; Aged; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Female; Humans; | 2016 |
Norfloxacin-induced hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Norfloxacin; Urinary Tract Infections | 1993 |
Norfloxacin-induced acute cholestatic hepatitis in a patient with alcoholic liver cirrhosis.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Chemical and Drug Induced Liver Injury; Cholestasis, | 1999 |
Norfloxacin-induced eosinophilic necrotizing granulomatous hepatitis.
Topics: Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Eosinophilic Granuloma; Female; | 2000 |
Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database.
Topics: Adult; Aged; Anti-Infective Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Ci | 2001 |
Norfloxacin-induced hepatotoxicity.
Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Norfloxacin | 1990 |