norfloxacin has been researched along with Blepharitis in 3 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Blepharitis: Inflammation of the eyelids.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this double-masked study, we randomly assigned 488 patients with clinical signs of acute bacterial conjunctivitis or blepharitis, or both, to treatment with either norfloxacin ophthalmic solution 0." | 9.07 | Topically administered norfloxacin compared with topically administered gentamicin for the treatment of external ocular bacterial infections. The Worldwide Norfloxacin Ophthalmic Study Group. ( Cook, TJ; Miller, IM; Vogel, R; Wittreich, J, 1992) |
| "Two hundred and forty-six patients with signs of acute bacterial conjunctivitis and/or blepharitis were randomised to receive either norfloxacin or chloramphenicol for one week in this double-masked parallel group study." | 5.07 | The safety and efficacy of topical norfloxacin compared with chloramphenicol for the treatment of external ocular bacterial infections. The Norfloxacin-Chloramphenicol Ophthalmic Study Group. ( Cook, T; Miller, IM; Vogel, R; Wittreich, JM, 1992) |
| "In this double-masked study, we randomly assigned 488 patients with clinical signs of acute bacterial conjunctivitis or blepharitis, or both, to treatment with either norfloxacin ophthalmic solution 0." | 5.07 | Topically administered norfloxacin compared with topically administered gentamicin for the treatment of external ocular bacterial infections. The Worldwide Norfloxacin Ophthalmic Study Group. ( Cook, TJ; Miller, IM; Vogel, R; Wittreich, J, 1992) |
| " No patients had serious adverse reactions attributed to their therapy." | 2.66 | Safety and efficacy of topical norfloxacin versus tobramycin in the treatment of external ocular infections. ( Call, NB; Dirks, MS; Jacobson, JA; Kasworm, EM; Turner, RB, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, IM | 2 |
| Wittreich, JM | 1 |
| Cook, T | 1 |
| Vogel, R | 2 |
| Cook, TJ | 1 |
| Wittreich, J | 1 |
| Jacobson, JA | 1 |
| Call, NB | 1 |
| Kasworm, EM | 1 |
| Dirks, MS | 1 |
| Turner, RB | 1 |
3 trials available for norfloxacin and Blepharitis
| Article | Year |
|---|---|
The safety and efficacy of topical norfloxacin compared with chloramphenicol for the treatment of external ocular bacterial infections. The Norfloxacin-Chloramphenicol Ophthalmic Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Blepharitis; Child; Child, Preschool; Chl | 1992 |
Topically administered norfloxacin compared with topically administered gentamicin for the treatment of external ocular bacterial infections. The Worldwide Norfloxacin Ophthalmic Study Group.
Topics: Administration, Topical; Adolescent; Adult; Aged; Bacterial Infections; Blepharitis; Conjunctivitis; | 1992 |
Safety and efficacy of topical norfloxacin versus tobramycin in the treatment of external ocular infections.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Blepharitis; Child; Child, Pres | 1988 |