norfloxacin has been researched along with Bacteriuria in 32 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Bacteriuria: The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and safety of a 5-day course of treatment with the new oral penem agent ritipenem acoxil (500 mg three times daily) or with norfloxacin (200 mg twice daily) were assessed in a double-blind study of women with uncomplicated cystitis." | 9.08 | Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin. Swedish Urinary Tract Infection Study Group. ( , 1995) |
| "In a coordinated, double-blind multi-centre trial, adults with symptoms of acute pyelonephritis were randomly assigned to receive a two-week course of oral treatment with either 400 mg norfloxacin twice daily or 1 g cefadroxil twice daily." | 9.06 | Randomised double-blind study of norfloxacin and cefadroxil in the treatment of acute pyelonephritis. ( Englund, G; Lincoln, K; Nilsson, LG; Sandberg, T, 1990) |
| "Three hundred and forty-three patients with suspected bacteriuria undergoing transurethral resection of the prostate (TUR-P) were randomized to treatment with either trimethoprim-sulfamethoxazole (TMP-SMX) or norfloxacin (NF) for 5 1/2 days beginning the evening prior to operation." | 9.06 | Norfloxacin versus trimethoprim-sulfamethoxazole. A study in patients with known bacteriuria undergoing transurethral resection of the prostate. ( Adolfsson, J; Falck, L; Köhler, C, 1989) |
| "The therapeutic efficacy and safety of norfloxacin 400 mg twice daily for 3 or 7 days was compared in a double-blind randomized multiclinic study including 485 female general practice patients with uncomplicated symptomatic lower urinary tract infections." | 9.06 | Double-blind comparison of 3-day versus 7-day treatment with norfloxacin in symptomatic urinary tract infections. The Inter-Nordic Urinary Tract Infection Study Group. ( , 1988) |
| "The efficacies of ofloxacin and norfloxacin in the treatment of chronic complicated urinary tract infections were compared." | 9.06 | Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections. ( Rugendorff, EW, 1987) |
| "One hundred and twenty-two patients with uncomplicated urinary tract infections were treated with either 400 mg bd norfloxacin or 160/800 mg bd cotrimoxazole for 7 days." | 9.05 | Norfloxacin versus cotrimoxazole in the treatment of uncomplicated urinary tract infections--a multi-centre trial. ( Chait, I; Deaney, NB; Kelsey, MC; Newsom, RA; Newsom, SW; Round, EM; Smith, J; Toase, PD; Vogel, R; Watt, B, 1984) |
| "Ninety-nine patients with simple symptomatic urinary tract infections from three general practices were treated with norfloxacin 400 mg bd for 3 days and were followed up for 2 to 4 weeks." | 7.67 | Treatment of simple urinary tract infections in general practice with a 3-day course of norfloxacin. ( Kirby, CP, 1984) |
| "One hundred and four patients with complicated urinary tract infections (prolonged severe chronic infections or with complicated postoperative conditions) were treated for ten days with pefloxacin 400 mg bid." | 7.67 | Efficacy and safety of pefloxacin in the treatment of patients with complicated urinary tract infections. ( Boerema, JB; Crombach, W; Pauwels, R; Scheepers, J, 1986) |
| "We compared the bactericidal activities of norfloxacin and nine other oral urinary tract antibiotics against 344 Gram-negative bacilli causing bacteriuria in chronically catheterized patients." | 7.66 | Bactericidal activity of norfloxacin and nine other urinary tract antibiotics against Gram-negative bacilli causing bacteriuria in chronically catheterized patients. ( Tenney, JH; Warren, JW, 1983) |
| "The efficacy and safety of a 5-day course of treatment with the new oral penem agent ritipenem acoxil (500 mg three times daily) or with norfloxacin (200 mg twice daily) were assessed in a double-blind study of women with uncomplicated cystitis." | 5.08 | Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin. Swedish Urinary Tract Infection Study Group. ( , 1995) |
| "In a coordinated, double-blind multi-centre trial, adults with symptoms of acute pyelonephritis were randomly assigned to receive a two-week course of oral treatment with either 400 mg norfloxacin twice daily or 1 g cefadroxil twice daily." | 5.06 | Randomised double-blind study of norfloxacin and cefadroxil in the treatment of acute pyelonephritis. ( Englund, G; Lincoln, K; Nilsson, LG; Sandberg, T, 1990) |
| "A randomized clinical study was conducted in order to compare the effectiveness of norfloxacin and cinoxacin in complicated urinary tract infections." | 5.06 | [Comparative evaluation of norfloxacin and cinoxacin in the therapy of complicated infections of the urinary tract]. ( Cristiano, P; Della Vittoria Scarpati, M; Iovene, MR; Manguso, L; Morelli, G; Simioli, F, 1989) |
| "Oral norfloxacin prevented Gram-negative bacilluria in female patients with hip fractures, who needed medium-term transurethral catheterization." | 5.06 | Prevention of catheter-associated gram-negative bacilluria with norfloxacin by selective decontamination of the bowel and high urinary concentration. ( Clasener, HA; Joosten, HJ; van Griethuysen, AJ; Vollaard, EJ; Zambon, JV, 1989) |
| "Three hundred and forty-three patients with suspected bacteriuria undergoing transurethral resection of the prostate (TUR-P) were randomized to treatment with either trimethoprim-sulfamethoxazole (TMP-SMX) or norfloxacin (NF) for 5 1/2 days beginning the evening prior to operation." | 5.06 | Norfloxacin versus trimethoprim-sulfamethoxazole. A study in patients with known bacteriuria undergoing transurethral resection of the prostate. ( Adolfsson, J; Falck, L; Köhler, C, 1989) |
| "The therapeutic efficacy and safety of norfloxacin 400 mg twice daily for 3 or 7 days was compared in a double-blind randomized multiclinic study including 485 female general practice patients with uncomplicated symptomatic lower urinary tract infections." | 5.06 | Double-blind comparison of 3-day versus 7-day treatment with norfloxacin in symptomatic urinary tract infections. The Inter-Nordic Urinary Tract Infection Study Group. ( , 1988) |
| "The efficacies of ofloxacin and norfloxacin in the treatment of chronic complicated urinary tract infections were compared." | 5.06 | Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections. ( Rugendorff, EW, 1987) |
| "One hundred and twenty-two patients with uncomplicated urinary tract infections were treated with either 400 mg bd norfloxacin or 160/800 mg bd cotrimoxazole for 7 days." | 5.05 | Norfloxacin versus cotrimoxazole in the treatment of uncomplicated urinary tract infections--a multi-centre trial. ( Chait, I; Deaney, NB; Kelsey, MC; Newsom, RA; Newsom, SW; Round, EM; Smith, J; Toase, PD; Vogel, R; Watt, B, 1984) |
| "Ninety-nine patients with simple symptomatic urinary tract infections from three general practices were treated with norfloxacin 400 mg bd for 3 days and were followed up for 2 to 4 weeks." | 3.67 | Treatment of simple urinary tract infections in general practice with a 3-day course of norfloxacin. ( Kirby, CP, 1984) |
| "The effect of once daily doses of 200 mg oral norfloxacin on the occurrence of catheter-associated bacteriuria (greater than 1000 CFU/ml) and pyuria was studied in 105 post-operative gynaecologic patients." | 3.67 | Postoperative prophylaxis with norfloxacin in patients requiring bladder catheters. ( Andriesse, R; Hamersma, K; Mintjes-de Groot, AJ; van Dijk, A; Verbrugh, HA, 1988) |
| "Twenty-four patients with complicated urinary tract infections were treated with norfloxacin for three months." | 3.67 | Norfloxacin treatment in complicated urinary tract infection. ( Boerema, JB; van Saene, HK, 1986) |
| "One hundred and four patients with complicated urinary tract infections (prolonged severe chronic infections or with complicated postoperative conditions) were treated for ten days with pefloxacin 400 mg bid." | 3.67 | Efficacy and safety of pefloxacin in the treatment of patients with complicated urinary tract infections. ( Boerema, JB; Crombach, W; Pauwels, R; Scheepers, J, 1986) |
| "We compared the bactericidal activities of norfloxacin and nine other oral urinary tract antibiotics against 344 Gram-negative bacilli causing bacteriuria in chronically catheterized patients." | 3.66 | Bactericidal activity of norfloxacin and nine other urinary tract antibiotics against Gram-negative bacilli causing bacteriuria in chronically catheterized patients. ( Tenney, JH; Warren, JW, 1983) |
| "Norfloxacin was as effective and safe as trimethoprim-sulfamethoxazole without emergence of resistant bacteria associated with trimethoprim-sulfamethoxazole." | 2.66 | Efficacy of norfloxacin in urinary tract infection biological effects on vaginal and fecal flora. ( Schaeffer, AJ; Sisney, GA, 1985) |
| "Bacteriuria is much more common in the elderly than in younger individuals for a variety of reasons." | 2.37 | A review of urinary tract infection in the elderly. ( Bendall, MJ, 1984) |
| " Enoxacin (250 mg/l) demonstrated the highest peak concentration (median) in the urine (0-6 h), followed by ciprofloxacin (237 mg/l) and norfloxacin (157 mg/l) as determined by the HPLC assay." | 1.30 | Urinary bactericidal activity and pharmacokinetics of enoxacin versus norfloxacin and ciprofloxacin in healthy volunteers after a single oral dose. ( Kinzig-Schippers, M; Naber, KG; Sörgel, F; Well, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (62.50) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bert, F | 1 |
| Leflon-Guibout, V | 1 |
| Le Grand, J | 1 |
| Bourdon, N | 1 |
| Nicolas-Chanoine, MH | 1 |
| Meiland, R | 1 |
| Geerlings, SE | 1 |
| De Neeling, AJ | 1 |
| Hoepelman, AI | 1 |
| Wilson, L | 1 |
| Ryan, J | 1 |
| Thelning, C | 1 |
| Masters, J | 1 |
| Tuckey, J | 1 |
| Tenney, JH | 1 |
| Warren, JW | 1 |
| Deaney, NB | 2 |
| Vogel, R | 2 |
| Vandenburg, MJ | 1 |
| Currie, WJ | 1 |
| Kirby, CP | 1 |
| Lacey, RW | 1 |
| Lord, VL | 1 |
| Howson, GL | 1 |
| Bendall, MJ | 1 |
| Watt, B | 1 |
| Chait, I | 1 |
| Kelsey, MC | 1 |
| Newsom, SW | 1 |
| Newsom, RA | 1 |
| Smith, J | 1 |
| Toase, PD | 1 |
| Round, EM | 1 |
| Arav-Boger, R | 1 |
| Leibovici, L | 1 |
| Danon, YL | 1 |
| Aguilar, L | 1 |
| Balcabao, IP | 1 |
| Salvá, P | 1 |
| Martín, M | 1 |
| Costa, J | 1 |
| Prieto, J | 1 |
| Dal-ré, R | 1 |
| Well, M | 1 |
| Naber, KG | 1 |
| Kinzig-Schippers, M | 1 |
| Sörgel, F | 1 |
| Cutajar, CL | 1 |
| Tzias, V | 1 |
| Dontas, AS | 1 |
| Petrikkos, G | 1 |
| Papapetropoulou, M | 1 |
| Dracopoulos, J | 1 |
| Giamarellou, H | 1 |
| Selvaggi, FP | 1 |
| Ditonno, P | 1 |
| Traficante, A | 1 |
| Battaglia, M | 1 |
| Di Lorenzo, V | 1 |
| Sandberg, T | 1 |
| Englund, G | 1 |
| Lincoln, K | 1 |
| Nilsson, LG | 1 |
| Boerema, JB | 3 |
| Willems, FT | 1 |
| Cristiano, P | 1 |
| Morelli, G | 1 |
| Simioli, F | 1 |
| Iovene, MR | 1 |
| Della Vittoria Scarpati, M | 1 |
| Manguso, L | 1 |
| Vollaard, EJ | 1 |
| Clasener, HA | 1 |
| Zambon, JV | 1 |
| Joosten, HJ | 1 |
| van Griethuysen, AJ | 1 |
| Adolfsson, J | 1 |
| Köhler, C | 1 |
| Falck, L | 1 |
| Galante, D | 1 |
| Pennucci, C | 1 |
| Esposito, S | 1 |
| Barba, D | 1 |
| Ewer, TC | 1 |
| Bailey, RR | 1 |
| Gilchrist, NL | 1 |
| Aitken, JM | 1 |
| Sainsbury, R | 1 |
| Sheehan, GJ | 1 |
| Harding, GK | 1 |
| Haase, DA | 1 |
| Thomson, MJ | 1 |
| Urias, B | 1 |
| Kennedy, JK | 1 |
| Hoban, DJ | 1 |
| Ronald, AR | 1 |
| Verbrugh, HA | 1 |
| Mintjes-de Groot, AJ | 1 |
| Andriesse, R | 1 |
| Hamersma, K | 1 |
| van Dijk, A | 1 |
| Schaeffer, AJ | 1 |
| Sisney, GA | 1 |
| van Saene, HK | 1 |
| Soriano, F | 1 |
| Ponte, C | 1 |
| Santamaría, M | 1 |
| Torres, A | 1 |
| Fernández-Roblas, R | 1 |
| Rugendorff, EW | 1 |
| Pauwels, R | 1 |
| Scheepers, J | 1 |
| Crombach, W | 1 |
| Karachalios, GN | 1 |
| Georgiopoulos, AN | 1 |
2 reviews available for norfloxacin and Bacteriuria
| Article | Year |
|---|---|
[Emergence of vancomycin-dependent enterococci following glycopeptide therapy: case report and review].
Topics: Bacterial Proteins; Bacteriuria; Carbon-Oxygen Ligases; Cecal Diseases; Ceftriaxone; Citrobacter fre | 2009 |
A review of urinary tract infection in the elderly.
Topics: Aged; Anti-Infective Agents, Urinary; Bacteriuria; Drug Combinations; Female; Humans; Male; Middle A | 1984 |
19 trials available for norfloxacin and Bacteriuria
| Article | Year |
|---|---|
Is antibiotic prophylaxis required for flexible cystoscopy? A truncated randomized double-blind controlled trial.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Bacteriuria; Cystoscopy; Double-Blind Method; Enteroc | 2005 |
Norfloxacin versus cotrimoxazole in the treatment of uncomplicated urinary tract infections--a multi-centre trial.
Topics: Anti-Infective Agents, Urinary; Bacteriuria; Drug Combinations; Female; Humans; Male; Nalidixic Acid | 1984 |
Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin. Swedish Urinary Tract Infection Study Group.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteriuria; Cystitis; Data Interpretation, Statisti | 1995 |
Urinary tract infections with low and high colony counts in young women. Spontaneous remission and single-dose vs multiple-day treatment.
Topics: Adolescent; Adult; Bacteriuria; Colony Count, Microbial; Drug Administration Schedule; Female; Human | 1994 |
Ex vivo antibacterial properties of rufloxacin compared with those of norfloxacin in a study with healthy volunteers.
Topics: Adult; Anti-Infective Agents; Bacteriuria; Cross-Over Studies; Escherichia coli Infections; Fluoroqu | 1996 |
Norfloxacin prophylaxis for endoscopic urological surgery.
Topics: Administration, Oral; Bacteremia; Bacteriuria; Endoscopy; Female; Humans; Kidney Calculi; Male; Norf | 1992 |
Three-day antibiotic therapy in bacteriuria of old age.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteriuria; Cefadroxil; Escherichia coli; Female; G | 1990 |
Fosfomycin trometamol (Monuril) versus norfloxacin in single dose for adult female uncomplicated UTIs. Multicenter randomized, double-blind study.
Topics: Adolescent; Adult; Aged; Bacteriuria; Double-Blind Method; Drug Administration Schedule; Female; Fos | 1990 |
Randomised double-blind study of norfloxacin and cefadroxil in the treatment of acute pyelonephritis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Bacteriuria; Cefadroxil; Chi-Square Distr | 1990 |
Fosfomycin trometamol in a single dose versus norfloxacin for seven days in the treatment of uncomplicated urinary infections in general practice.
Topics: Adolescent; Adult; Bacteriuria; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; E | 1990 |
[Comparative evaluation of norfloxacin and cinoxacin in the therapy of complicated infections of the urinary tract].
Topics: Bacteria; Bacteriuria; Cinoxacin; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Male; Mi | 1989 |
Prevention of catheter-associated gram-negative bacilluria with norfloxacin by selective decontamination of the bowel and high urinary concentration.
Topics: Aged; Aged, 80 and over; Amphotericin B; Bacteriuria; Candida albicans; Digestive System; Feces; Fem | 1989 |
Norfloxacin versus trimethoprim-sulfamethoxazole. A study in patients with known bacteriuria undergoing transurethral resection of the prostate.
Topics: Aged; Aged, 80 and over; Bacteriuria; Humans; Male; Middle Aged; Multicenter Studies as Topic; Norfl | 1989 |
Double-blind comparison of 3-day versus 7-day treatment with norfloxacin in symptomatic urinary tract infections. The Inter-Nordic Urinary Tract Infection Study Group.
Topics: Bacteriuria; Double-Blind Method; Drug Administration Schedule; Female; Humans; Middle Aged; Norflox | 1988 |
Comparative study of norfloxacin and trimethoprim for the treatment of elderly patients with urinary tract infection.
Topics: Aged; Aged, 80 and over; Bacterial Infections; Bacteriuria; Clinical Trials as Topic; Enterobacteria | 1988 |
Double-blind, randomized comparison of 24 weeks of norfloxacin and 12 weeks of norfloxacin followed by 12 weeks of placebo in the therapy of complicated urinary tract infection.
Topics: Bacteriuria; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Humans; No | 1988 |
Efficacy of norfloxacin in urinary tract infection biological effects on vaginal and fecal flora.
Topics: Adult; Anal Canal; Anti-Infective Agents, Urinary; Bacteriuria; Drug Combinations; Drug Resistance, | 1985 |
Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections.
Topics: Adult; Anti-Infective Agents; Bacteriuria; Female; Humans; Male; Microbial Sensitivity Tests; Norflo | 1987 |
Norfloxacin versus nalidixic acid in the treatment of urinary tract infections.
Topics: Adult; Aged; Bacterial Infections; Bacteriuria; Female; Humans; Male; Middle Aged; Nalidixic Acid; N | 1987 |
11 other studies available for norfloxacin and Bacteriuria
| Article | Year |
|---|---|
Diabetes mellitus in itself is not a risk factor for antibiotic resistance in Escherichia coli isolated from patients with bacteriuria.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Bacteriuria; Ciprofloxacin; Diabetes Co | 2004 |
Bactericidal activity of norfloxacin and nine other urinary tract antibiotics against Gram-negative bacilli causing bacteriuria in chronically catheterized patients.
Topics: Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Catheterization; Cinoxacin; Humans; Microbial | 1983 |
Norfloxacin in acute urinary tract infections.
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacteriuria; Child; Female; | 1984 |
Treatment of simple urinary tract infections in general practice with a 3-day course of norfloxacin.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Child; Drug Resistance, Microb | 1984 |
Bactericidal effects of norfloxacin towards bacteria in urine.
Topics: Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Blood Bactericidal Activity; Enterobacteriace | 1984 |
Urinary bactericidal activity and pharmacokinetics of enoxacin versus norfloxacin and ciprofloxacin in healthy volunteers after a single oral dose.
Topics: Administration, Oral; Adult; Bacteriuria; Calibration; Chromatography, High Pressure Liquid; Ciprofl | 1998 |
Comparative in vitro activity of ciprofloxacin and five other quinoline derivatives against gram-negative isolates.
Topics: Bacteriuria; Cinoxacin; Ciprofloxacin; Gram-Negative Bacteria; Humans; In Vitro Techniques; Microbia | 1985 |
Postoperative prophylaxis with norfloxacin in patients requiring bladder catheters.
Topics: Adult; Aged; Aged, 80 and over; Alcaligenes; Bacteriuria; Catheters, Indwelling; Cross Infection; En | 1988 |
Norfloxacin treatment in complicated urinary tract infection.
Topics: Adolescent; Adult; Aged; Bacteriuria; Child; Enterobacteriaceae Infections; Female; Humans; Male; Mi | 1986 |
Susceptibility of urinary isolates of Corynebacterium group D2 to fifteen antimicrobials and acetohydroxamic acid.
Topics: Anti-Bacterial Agents; Bacteriuria; Corynebacterium; Humans; Hydrogen-Ion Concentration; Hydroxamic | 1987 |
Efficacy and safety of pefloxacin in the treatment of patients with complicated urinary tract infections.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacteriuria; Drug Evaluation; Escherichia | 1986 |