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norfloxacin and Bacterial Eye Infections

norfloxacin has been researched along with Bacterial Eye Infections in 12 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Research Excerpts

ExcerptRelevanceReference
"In this double-masked study, we randomly assigned 488 patients with clinical signs of acute bacterial conjunctivitis or blepharitis, or both, to treatment with either norfloxacin ophthalmic solution 0."9.07Topically administered norfloxacin compared with topically administered gentamicin for the treatment of external ocular bacterial infections. The Worldwide Norfloxacin Ophthalmic Study Group. ( Cook, TJ; Miller, IM; Vogel, R; Wittreich, J, 1992)
"We present three cases of norfloxacin deposits after treatment of bacterial keratitis."7.69Deposits of topical norfloxacin in the treatment of bacterial keratitis. ( Benitez del Castillo, JM; Castillo, A; Diaz-Valle, D; Garcia-Sanchez, J; Sayagues, O; Toledano, N, 1997)
"In this double-masked study, we randomly assigned 488 patients with clinical signs of acute bacterial conjunctivitis or blepharitis, or both, to treatment with either norfloxacin ophthalmic solution 0."5.07Topically administered norfloxacin compared with topically administered gentamicin for the treatment of external ocular bacterial infections. The Worldwide Norfloxacin Ophthalmic Study Group. ( Cook, TJ; Miller, IM; Vogel, R; Wittreich, J, 1992)
"We present three cases of norfloxacin deposits after treatment of bacterial keratitis."3.69Deposits of topical norfloxacin in the treatment of bacterial keratitis. ( Benitez del Castillo, JM; Castillo, A; Diaz-Valle, D; Garcia-Sanchez, J; Sayagues, O; Toledano, N, 1997)
"Rickettsial diseases such as murine typhus should be included in the differential diagnosis of otherwise healthy individuals who present with an acute systemic febrile illness and retinitis or neuroretinitis."2.40Retinal manifestations of acute murine typhus. ( Hudson, HL; Lopez, PF; Thach, AB, 1997)
"Ciprofloxacin was significantly more effective than norfloxacin in reducing the number of bacteria per cornea (P less than 0."1.28Quinolones in collagen shields to treat aminoglycoside-resistant pseudomonal keratitis. ( Hill, JM; Hobden, JA; Insler, MS; O'Callaghan, RJ; Reidy, JJ, 1990)
"Norfloxacin is a synthetic antibiotic belonging to the fluoroquinolone class."1.28[Norfloxacin: a broad-spectrum quinolone for superficial eye infections]. ( Grosset, J, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's10 (83.33)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garty, S1
Shirakawa, R1
Warsen, A1
Anderson, EM1
Noble, ML1
Bryers, JD1
Ratner, BD1
Shen, TT1
Koguchi, M1
Suzuki, Y1
Tanaka, S1
Fukayama, S1
Ishihara, R1
Deguchi, K1
Oda, S1
Nakane, Y1
Fukumoto, T1
Diamond, JP1
White, L1
Leeming, JP1
Bing Hoh, H1
Easty, DL1
Castillo, A1
Benitez del Castillo, JM1
Toledano, N1
Diaz-Valle, D1
Sayagues, O1
Garcia-Sanchez, J1
Hudson, HL1
Thach, AB1
Lopez, PF1
Yolton, DP1
Huber-Spitzy, V1
Arocker-Mettinger, E1
Steurer-Georgiew, L1
SchiffbÀnker, M1
Miller, IM1
Vogel, R1
Cook, TJ1
Wittreich, J1
Vajpayee, RB1
Gupta, SK1
Angra, SK1
Munjal, A1
Hobden, JA1
Reidy, JJ1
O'Callaghan, RJ1
Insler, MS1
Hill, JM1
Grosset, J1
Kestelyn, P1
Bogaerts, J1
Stevens, AM1
Piot, P1
Meheus, A1

Reviews

2 reviews available for norfloxacin and Bacterial Eye Infections

ArticleYear
Retinal manifestations of acute murine typhus.
    International ophthalmology, 1997, Volume: 21, Issue:3

    Topics: Acute Disease; Adult; Antibodies, Bacterial; Diagnosis, Differential; Doxycycline; Eye Infections, B

1997
New antibacterial drugs for topical ophthalmic use.
    Optometry clinics : the official publication of the Prentice Society, 1992, Volume: 2, Issue:4

    Topics: Ciprofloxacin; Conjunctivitis, Bacterial; Corneal Ulcer; Drug Therapy, Combination; Eye Infections,

1992

Trials

2 trials available for norfloxacin and Bacterial Eye Infections

ArticleYear
Topically administered norfloxacin compared with topically administered gentamicin for the treatment of external ocular bacterial infections. The Worldwide Norfloxacin Ophthalmic Study Group.
    American journal of ophthalmology, 1992, Jun-15, Volume: 113, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Bacterial Infections; Blepharitis; Conjunctivitis;

1992
Treatment of adult gonococcal keratoconjunctivitis with oral norfloxacin.
    American journal of ophthalmology, 1989, Nov-15, Volume: 108, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Conjunctiva; Eye Infections, Bact

1989

Other Studies

8 other studies available for norfloxacin and Bacterial Eye Infections

ArticleYear
Sustained antibiotic release from an intraocular lens-hydrogel assembly for cataract surgery.
    Investigative ophthalmology & visual science, 2011, Aug-03, Volume: 52, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Cataract Extraction; Coated Materials, Biocompatible; Colony Count,

2011
[Antimicrobial activities of norfloxacin against clinical isolates from ocular infections].
    The Japanese journal of antibiotics, 1995, Volume: 48, Issue:8

    Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Eye Infections, Bacterial; Humans; Norf

1995
Topical 0.3% ciprofloxacin, norfloxacin, and ofloxacin in treatment of bacterial keratitis: a new method for comparative evaluation of ocular drug penetration.
    The British journal of ophthalmology, 1995, Volume: 79, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chromatography, High Pressure Liquid; Ciprofloxac

1995
Deposits of topical norfloxacin in the treatment of bacterial keratitis.
    Cornea, 1997, Volume: 16, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Chemical Precipitation; Cornea; Corneal Diseases; Cr

1997
[Treatment of Ocular Chlamydial Infection: Comparison of Tetracyclines and Norfloxacin].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1992, Volume: 205, Issue:2

    Topics: Adolescent; Adult; Chlamydia Infections; Cornea; Eye Infections, Bacterial; Female; Humans; Keratoco

1992
Topical norfloxacin therapy in Pseudomonas corneal ulceration.
    Cornea, 1991, Volume: 10, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Child; Cornea; Corneal Ulcer; Eye Infections, Bacterial;

1991
Quinolones in collagen shields to treat aminoglycoside-resistant pseudomonal keratitis.
    Investigative ophthalmology & visual science, 1990, Volume: 31, Issue:11

    Topics: Animals; Ciprofloxacin; Collagen; Colony Count, Microbial; Cornea; Drug Resistance, Microbial; Eye I

1990
[Norfloxacin: a broad-spectrum quinolone for superficial eye infections].
    Pathologie-biologie, 1990, Volume: 38, Issue:7

    Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Eye Infections,

1990