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norfloxacin and Bacterial Conjunctivitides

norfloxacin has been researched along with Bacterial Conjunctivitides in 7 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to estimate changes in bacterial flora of conjunctival sac changes in patients prophylacticaly treated with different antibiotics (chloramphenicol, gentamycin, ofloxacin, norfloxacin) before cataract operation."5.11[Changes in bacterial flora of conjunctival sac in patients prophylacticaly treated with antibiotic before cataract operation]. ( Gerkowicz, M; Gruszecka-Gerkowicz, R; Kosior-Jarecka, E; Pietraś-Trzpiel, M, 2005)
"Two hundred and forty-six patients with signs of acute bacterial conjunctivitis and/or blepharitis were randomised to receive either norfloxacin or chloramphenicol for one week in this double-masked parallel group study."5.07The safety and efficacy of topical norfloxacin compared with chloramphenicol for the treatment of external ocular bacterial infections. The Norfloxacin-Chloramphenicol Ophthalmic Study Group. ( Cook, T; Miller, IM; Vogel, R; Wittreich, JM, 1992)
" No patients had serious adverse reactions attributed to their therapy."2.66Safety and efficacy of topical norfloxacin versus tobramycin in the treatment of external ocular infections. ( Call, NB; Dirks, MS; Jacobson, JA; Kasworm, EM; Turner, RB, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chisari, G1
Sanfilippo, M1
Reibaldi, M1
Gerkowicz, M1
Gruszecka-Gerkowicz, R1
Kosior-Jarecka, E1
Pietraś-Trzpiel, M1
Drago, F1
La Manna, C1
Marino, V1
Marino, A1
Emmi, I1
Reibaldi, A1
Yolton, DP1
Miller, IM1
Wittreich, JM1
Cook, T1
Vogel, R1
Avisar, R1
Vender, T1
Savir, H1
Lerner, N1
Hundart, O1
Yasur, Y1
Jacobson, JA1
Call, NB1
Kasworm, EM1
Dirks, MS1
Turner, RB1

Reviews

1 review available for norfloxacin and Bacterial Conjunctivitides

ArticleYear
New antibacterial drugs for topical ophthalmic use.
    Optometry clinics : the official publication of the Prentice Society, 1992, Volume: 2, Issue:4

    Topics: Ciprofloxacin; Conjunctivitis, Bacterial; Corneal Ulcer; Drug Therapy, Combination; Eye Infections,

1992

Trials

5 trials available for norfloxacin and Bacterial Conjunctivitides

ArticleYear
[Treatment of bacterial conjuntivitis with topical ciprofloxacin and norfloxacin: a comparative study].
    Le infezioni in medicina, 2003, Volume: 11, Issue:1

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Ciprofloxacin; Conjunctivitis, Bacterial; Fem

2003
[Changes in bacterial flora of conjunctival sac in patients prophylacticaly treated with antibiotic before cataract operation].
    Klinika oczna, 2005, Volume: 107, Issue:10-12

    Topics: Antibiotic Prophylaxis; Cataract; Cataract Extraction; Chloramphenicol; Conjunctiva; Conjunctivitis,

2005
Norfloxacin exhibits negligible serum concentrations after repeated conjunctival instillation in children.
    British journal of clinical pharmacology, 1998, Volume: 46, Issue:3

    Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Conjunctiva; Conjunctivitis, Bacterial;

1998
The safety and efficacy of topical norfloxacin compared with chloramphenicol for the treatment of external ocular bacterial infections. The Norfloxacin-Chloramphenicol Ophthalmic Study Group.
    Eye (London, England), 1992, Volume: 6 ( Pt 1)

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Blepharitis; Child; Child, Preschool; Chl

1992
Safety and efficacy of topical norfloxacin versus tobramycin in the treatment of external ocular infections.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:12

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Blepharitis; Child; Child, Pres

1988

Other Studies

1 other study available for norfloxacin and Bacterial Conjunctivitides

ArticleYear
Norfloxacin ophthalmic versus chloramphenicol in bacterial conjunctivitis and blepharoconjunctivitis.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:6

    Topics: Chloramphenicol; Conjunctivitis, Bacterial; Humans; Norfloxacin

1990