Page last updated: 2024-11-01

norfloxacin and Bacteremia

norfloxacin has been researched along with Bacteremia in 16 studies

Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.

Research Excerpts

ExcerptRelevanceReference
"We performed a 5-year retrospective study to evaluate the effect of long-term administration of norfloxacin on the epidemiology of severe hospital-acquired infections in patients with advanced cirrhosis."5.30Epidemiology of severe hospital-acquired infections in patients with liver cirrhosis: effect of long-term administration of norfloxacin. ( Campillo, B; Dupeyron, C; Leluan, G; Mangeney, N; Richardet, JP, 1998)
"Oral norfloxacin is the standard of therapy in the prophylaxis of bacterial infections in cirrhotic patients with gastrointestinal hemorrhage."5.12Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage. ( Arroyo, V; Durandez, R; Fernández, J; Gómez, C; Guarner, C; Navasa, M; Planas, R; Ruiz del Arbol, L; Serradilla, R, 2006)
" For primary prophylaxis, short-term antibiotic treatment (oral norfloxacin or ciprofloxacin) is indicated in cirrhotic patients (with or without ascites) admitted with gastrointestinal haemorrhage (variceal or non-variceal)."4.84[Bacterial infections in liver cirrhosis]. ( Farkas, A; Papp, M; Tornai, I; Udvardy, M, 2007)
"To determine the relative importance of temperate bacteriophage in the horizontal gene transfer of fitness and virulence determinants of Enterococcus faecalis, a panel of 47 bacteremia isolates were treated with the inducing agents mitomycin C, norfloxacin, and UV radiation."3.76Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages. ( Darby, AC; Edwards, C; Hall, N; Horsburgh, MJ; Kenny, JG; Shankar, J; Yasmin, A, 2010)
"We performed a 5-year retrospective study to evaluate the effect of long-term administration of norfloxacin on the epidemiology of severe hospital-acquired infections in patients with advanced cirrhosis."1.30Epidemiology of severe hospital-acquired infections in patients with liver cirrhosis: effect of long-term administration of norfloxacin. ( Campillo, B; Dupeyron, C; Leluan, G; Mangeney, N; Richardet, JP, 1998)
"Various neuropsychiatric syndromes in typhoid fever were seen in nine patients of multiple drug resistant (both in vitro and in vivo) Salmonella typhi infection of a total of 270 suspected cases in the last two years."1.28Neuropsychiatric manifestations of typhoid fever. ( Ali, G; Allaqaband, GQ; Aziz, A; Hussain, A; Kamili, MA; Koul, RL; Shah, MY, 1992)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's10 (62.50)18.2507
2000's3 (18.75)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lontos, S1
Shelton, E1
Angus, PW1
Vaughan, R1
Roberts, SK1
Gordon, A1
Gow, PJ1
Yasmin, A1
Kenny, JG1
Shankar, J1
Darby, AC1
Hall, N1
Edwards, C1
Horsburgh, MJ1
Pantosti, A1
Giuliano, M1
Gentile, G1
Cardines, R1
Santilli, S1
Mandelli, F1
Martino, P1
Fernández, J1
Ruiz del Arbol, L1
Gómez, C1
Durandez, R1
Serradilla, R1
Guarner, C1
Planas, R1
Arroyo, V1
Navasa, M1
Papp, M1
Farkas, A1
Udvardy, M1
Tornai, I1
Carratalá, J1
Fernández-Sevilla, A1
Tubau, F1
Callis, M1
Gudiol, F1
Broun, ER1
Wheat, JL1
Kneebone, PH1
Sundblad, K1
Hromas, RA1
Tricot, G1
Cogollos, R1
Alós, JI1
Gómez-Garcés, JL1
Imperiale, TF1
Esber, EJ1
Bow, EJ1
Mandell, LA1
Louie, TJ1
Feld, R1
Palmer, M1
Zee, B1
Pater, J1
Campillo, B1
Dupeyron, C1
Richardet, JP1
Mangeney, N1
Leluan, G1
Martino, R1
Subira, M1
Altés, A1
López, R1
Sureda, A1
Domingo-Albós, A1
Pericas, R1
Brunet, S1
Rodríguez-Avial, I1
Rodríguez-Avial, C1
Picazo, JJ1
D'Antonio, D1
Iacone, A1
Fioritoni, G1
Betti, S1
Dell'Isola, M1
Quaglietta, AM1
Accorsi, P1
Pantalone, V1
Recchia, A1
Piergallini, A1
Ali, G1
Kamili, MA1
Shah, MY1
Koul, RL1
Aziz, A1
Hussain, A1
Allaqaband, GQ1
Cutajar, CL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis in Patients With Acute Variceal Bleeding[NCT00838864]Phase 479 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for norfloxacin and Bacteremia

ArticleYear
[Bacterial infections in liver cirrhosis].
    Orvosi hetilap, 2007, Mar-04, Volume: 148, Issue:9

    Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ascites;

2007

Trials

6 trials available for norfloxacin and Bacteremia

ArticleYear
A randomized controlled study of trimethoprim-sulfamethoxazole versus norfloxacin for the prevention of infection in cirrhotic patients.
    Journal of digestive diseases, 2014, Volume: 15, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Bacterial I

2014
Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage.
    Gastroenterology, 2006, Volume: 131, Issue:4

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Ba

2006
Randomized trial of the addition of gram-positive prophylaxis to standard antimicrobial prophylaxis for patients undergoing autologous bone marrow transplantation.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3

    Topics: Acyclovir; Adult; Bacteremia; Bone Marrow Transplantation; Female; Fever; Fluconazole; Gram-Positive

1994
Quinolone-based antibacterial chemoprophylaxis in neutropenic patients: effect of augmented gram-positive activity on infectious morbidity. National Cancer Institute of Canada Clinical Trials Group.
    Annals of internal medicine, 1996, Aug-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents; Antineoplastic Agents; Bacteremia; Colony Count, Microbial; Fema

1996
Comparison of norfloxacin and pefloxacin in the prophylaxis of bacterial infection in neutropenic cancer patients.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bacteremia; Bacterial Infections; Female; Fever; Hum

1992
Norfloxacin prophylaxis for endoscopic urological surgery.
    British journal of urology, 1992, Volume: 69, Issue:4

    Topics: Administration, Oral; Bacteremia; Bacteriuria; Endoscopy; Female; Humans; Kidney Calculi; Male; Norf

1992

Other Studies

9 other studies available for norfloxacin and Bacteremia

ArticleYear
Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages.
    Journal of bacteriology, 2010, Volume: 192, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Bacteriophages; DNA Fingerprinting; DNA, Viral; Electrophoresis,

2010
Anaerobic bacteremia in bone marrow recipients.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Bacteria, Anaerobic; Bone Marrow Tr

1989
Emergence of quinolone-resistant Escherichia coli bacteremia in neutropenic patients with cancer who have received prophylactic norfloxacin.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 20, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Bacteremia; Drug Resistance, Microbial; Escherichia coli Infections;

1995
[Evolution of fluoroquinolone sensitivity in Staphylococcus aureus isolated from hemocultures in a general hospital].
    Enfermedades infecciosas y microbiologia clinica, 1993, Volume: 11, Issue:8

    Topics: Bacteremia; Blood; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Hospitals, General; H

1993
Preventing infection in cirrhotics with gastrointestinal hemorrhage.
    Gastroenterology, 1993, Volume: 104, Issue:4

    Topics: Bacteremia; Bacterial Infections; Biometry; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; No

1993
Epidemiology of severe hospital-acquired infections in patients with liver cirrhosis: effect of long-term administration of norfloxacin.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:5

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Ascitic Fluid; Bacteremia; Cross Infection; Dru

1998
Effect of discontinuing prophylaxis with norfloxacin in patients with hematologic malignancies and severe neutropenia. A matched case-control study of the effect on infectious morbidity.
    Acta haematologica, 1998, Volume: 99, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Bacterial Infect

1998
[In vitro activity of six fluoroquinolones and penicillin against 101 viridans group streptococci characterized by their susceptibility to erythromycin].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2001, Volume: 14, Issue:4

    Topics: Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Drug Resistance; Drug Resistance, M

2001
Neuropsychiatric manifestations of typhoid fever.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Bacteremia; Drug Resistance, Microbial; Female; Humans; Male; Mental Disorders; N

1992