norfloxacin has been researched along with Aging in 2 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Norfloxacin was poorly absorbed after oral administration (60 mg." | 1.30 | Age-related differences in norfloxacin pharmacokinetic behaviour following intravenous and oral administration in sheep. ( De Vicente, ML; González, F; Nieto, J; Rodríguez, C; San Andrés, MD; San Andrés, MI, 1997) |
| " Norfloxacin and nalidixic acid were subcutaneously administered to rats and rabbits, orally administered to dogs, and norfloxacin was orally dosed to monkeys once a day for 7 consecutive days." | 1.28 | Toxicokinetic study of norfloxacin-induced arthropathy in juvenile animals. ( Aijima, H; Ishida, R; Kusajima, H; Machida, M; Maeda, A; Uchida, H, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González, F | 1 |
| Rodríguez, C | 1 |
| Nieto, J | 1 |
| De Vicente, ML | 1 |
| San Andrés, MD | 1 |
| San Andrés, MI | 1 |
| Machida, M | 1 |
| Kusajima, H | 1 |
| Aijima, H | 1 |
| Maeda, A | 1 |
| Ishida, R | 1 |
| Uchida, H | 1 |
2 other studies available for norfloxacin and Aging
| Article | Year |
|---|---|
Age-related differences in norfloxacin pharmacokinetic behaviour following intravenous and oral administration in sheep.
Topics: Absorption; Administration, Oral; Aging; Animals; Anti-Infective Agents; Biological Availability; Cr | 1997 |
Toxicokinetic study of norfloxacin-induced arthropathy in juvenile animals.
Topics: Administration, Oral; Aging; Animals; Dogs; Dose-Response Relationship, Drug; Joint Diseases; Joints | 1990 |