norfloxacin has been researched along with Acute Liver Injury, Drug-Induced in 12 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Norfloxacin administration is useful in preventing bacterial infections in cirrhosis but associated to the generation of resistant species." | 3.88 | Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis. ( Bellot, P; Francés, R; García, I; Gimenez, P; Gómez-Hurtado, I; González-Navajas, JM; Guarner, F; Manichanh, C; Ramos, JM; Such, J; Zapater, P, 2018) |
| " In this study, we investigated the toxic effects of carp exposed to 0, 100 ng/L, and 1 mg/L norfloxacin (NOR) at environmental concentrations for 42 days." | 1.62 | Hepatotoxicity in carp (Cyprinus carpio) exposed to environmental levels of norfloxacin (NOR): Some latest evidences from transcriptomics analysis, biochemical parameters and histopathological changes. ( Cao, ZH; He, SW; Li, P; Li, ZH; Xing, SY; Zhang, HQ; Zhang, SQ; Zhao, XL, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Zhang, SQ | 1 |
| Li, P | 1 |
| Zhao, XL | 1 |
| He, SW | 1 |
| Xing, SY | 1 |
| Cao, ZH | 1 |
| Zhang, HQ | 1 |
| Li, ZH | 1 |
| Gómez-Hurtado, I | 1 |
| Gimenez, P | 1 |
| García, I | 1 |
| Zapater, P | 1 |
| Francés, R | 1 |
| González-Navajas, JM | 1 |
| Manichanh, C | 1 |
| Ramos, JM | 1 |
| Bellot, P | 1 |
| Guarner, F | 1 |
| Such, J | 1 |
| Elliott, TR | 1 |
| Symes, T | 1 |
| Kannourakis, G | 1 |
| Angus, P | 1 |
| Davoren, P | 1 |
| Mainstone, K | 1 |
| Romero-Gómez, M | 1 |
| Suárez García, E | 1 |
| Fernández, MC | 1 |
| Björnsson, E | 1 |
| Olsson, R | 1 |
| Remotti, H | 1 |
| Clark, DW | 1 |
| Layton, D | 1 |
| Wilton, LV | 1 |
| Pearce, GL | 1 |
| Shakir, SA | 1 |
| López-Navidad, A | 1 |
| Domingo, P | 1 |
| Cadafalch, J | 1 |
| Farrerons, J | 1 |
1 review available for norfloxacin and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
11 other studies available for norfloxacin and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Hepatotoxicity in carp (Cyprinus carpio) exposed to environmental levels of norfloxacin (NOR): Some latest evidences from transcriptomics analysis, biochemical parameters and histopathological changes.
Topics: Animals; Carps; Chemical and Drug Induced Liver Injury; Liver; Norfloxacin; Transcriptome; Water Pol | 2021 |
Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Bacterial Translocation; Carbon Tetrachloride; | 2018 |
Resolution of norfloxacin-induced acute liver failure after N-acetylcysteine therapy: further support for the use of NAC in drug-induced ALF?
Topics: Acetylcysteine; Aged; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Female; Humans; | 2016 |
Norfloxacin-induced hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Norfloxacin; Urinary Tract Infections | 1993 |
Norfloxacin-induced acute cholestatic hepatitis in a patient with alcoholic liver cirrhosis.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Chemical and Drug Induced Liver Injury; Cholestasis, | 1999 |
Norfloxacin-induced eosinophilic necrotizing granulomatous hepatitis.
Topics: Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Eosinophilic Granuloma; Female; | 2000 |
Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database.
Topics: Adult; Aged; Anti-Infective Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Ci | 2001 |
Norfloxacin-induced hepatotoxicity.
Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Norfloxacin | 1990 |