norfloxacin has been researched along with Acquired Immunodeficiency Syndrome in 3 studies
Norfloxacin: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
norfloxacin : A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral administration and twice daily dosing are significant advantages." | 1.27 | Norfloxacin in the eradication of enteric infections in AIDS patients. ( Appleman, MD; Causey, DM; Corrado, ML; Heseltine, PN; Leedom, JM, 1988) |
| "Norfloxacin treatment resulted in clinical cure or improvement in 84 percent of patients and eradicated the etiologic pathogen(s) 52 percent of the time." | 1.27 | Compassionate use of norfloxacin. ( Corrado, ML; Heseltine, PN, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nozaki-Renard, J | 1 |
| Iino, T | 1 |
| Sato, Y | 1 |
| Marumoto, Y | 1 |
| Ohta, G | 1 |
| Furusawa, M | 1 |
| Heseltine, PN | 2 |
| Causey, DM | 1 |
| Appleman, MD | 1 |
| Corrado, ML | 2 |
| Leedom, JM | 1 |
3 other studies available for norfloxacin and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Cell Survival; Ciprofloxacin; Enoxacin; HIV-1; Humans | 1990 |
Norfloxacin in the eradication of enteric infections in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Humans; Intestinal Diseases; Male; Norfloxacin; Recurrenc | 1988 |
Compassionate use of norfloxacin.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections | 1987 |