Page last updated: 2024-08-21

norfenfluramine and Obesity

norfenfluramine has been researched along with Obesity in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, KJ1
Chalmers, SR; Douglas, JG; Frazer, I; Gough, J; Haslett, C; Munro, JF; Preston, PG1
Bareggi, SR; Boni, S; Bonini, LM; Magnoni, V; Zecca, L1
Wales, JK1
Rowland, NE1
Bizzi, A; Garattini, S; Morselli, PL; Tacconi, MT; Tognoni, G1
Campbell, DB; Ford, MJ; Innes, JA; Munro, JF; Stoddart, ME; Watson, ML1
Macrae, SM1
Campbell, DB; Hossain, M1
Carlton, J; Rowland, NE1
Caccia, S; Fracasso, C; Garattini, S; Guiso, G1
Beeley, NR; Bjenning, C; Chen, RR; Covel, JA; Dosa, PI; Espitia, S; Estrada, SA; Gallardo, CS; Gilson, CA; Grottick, AJ; Martin, M; Menzaghi, F; Morgan, M; Park, DM; Prieto, EB; Ren, A; Saldana, HR; Schultz, JA; Sengupta, D; Smith, BM; Smith, JM; Thomsen, WJ; Tsai, JH; Webb, RR; Whelan, KT1

Reviews

3 review(s) available for norfenfluramine and Obesity

ArticleYear
Serotonin 5-ht2c receptor agonists: potential for the treatment of obesity.
    Molecular interventions, 2005, Volume: 5, Issue:5

    Topics: Animals; Fenfluramine; Humans; Norfenfluramine; Obesity; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists; Treatment Outcome

2005
Peripheral and metabolic effects of fenfluramine, 780SE, norfenfluramine and hydroxyethylnorfenfluramine--a review.
    Postgraduate medical journal, 1975, Volume: 51 Suppl 1

    Topics: Adipose Tissue; Amphetamines; Animals; Autonomic Nervous System; Blood Pressure; Cats; Dogs; Fenfluramine; Glucose; Guinea Pigs; Humans; Lipid Metabolism; Muscles; Norfenfluramine; Obesity; Rabbits; Rats; Structure-Activity Relationship; Triglycerides

1975
Tolerance to fenfluramine anorexia: fact or fiction?
    Appetite, 1986, Volume: 7 Suppl

    Topics: Animals; Behavior Therapy; Body Weight; Brain; Brain Chemistry; Drug Tolerance; Feeding Behavior; Female; Fenfluramine; Gastric Emptying; Hydroxyindoleacetic Acid; Intestines; Male; Norfenfluramine; Obesity; Rats; Rats, Inbred Strains; Self Stimulation; Serotonin; Stomach

1986

Trials

3 trial(s) available for norfenfluramine and Obesity

ArticleYear
Long-term efficacy of fenfluramine in treatment of obesity.
    Lancet (London, England), 1983, Feb-19, Volume: 1, Issue:8321

    Topics: Body Weight; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Fenfluramine; Humans; Hypertension, Pulmonary; Norfenfluramine; Obesity; Recurrence; Tablets; Time Factors

1983
Plasma fenfluramine levels, weight loss, and side effects.
    British medical journal, 1977, Nov-19, Volume: 2, Issue:6098

    Topics: Adult; Aged; Body Weight; Female; Fenfluramine; Humans; Middle Aged; Norfenfluramine; Obesity

1977
Fenfluramine and methylcellulose in the treatment of obesity: the relationship between plasma drug concentrations and therapeutic efficacy.
    Postgraduate medical journal, 1975, Volume: 51 Suppl 1

    Topics: Adolescent; Adult; Aged; Biological Availability; Clinical Trials as Topic; Diet, Reducing; Female; Fenfluramine; Humans; Male; Methylcellulose; Middle Aged; Norfenfluramine; Obesity

1975

Other Studies

6 other study(ies) available for norfenfluramine and Obesity

ArticleYear
[Activity of fenfluramine in obese subjects. Relation between dosage, plasma concentration of the drug and its effect on weight loss].
    Minerva medica, 1982, Jun-08, Volume: 73, Issue:24

    Topics: Adult; Aged; Body Weight; Dose-Response Relationship, Drug; Female; Fenfluramine; Humans; Male; Middle Aged; Norfenfluramine; Obesity

1982
The effect of fenfluramine on weight loss during restricted dietary regimes.
    International journal of obesity, 1980, Volume: 4, Issue:2

    Topics: Body Weight; Female; Fenfluramine; Humans; Male; Norfenfluramine; Obesity

1980
Long-term administration of dexfenfluramine to genetically obese (ob/ob) and lean mice: body weight and brain serotonin changes.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Brain Chemistry; Corticosterone; Dietary Fats; Female; Fenfluramine; Mice; Mice, Inbred C57BL; Mice, Obese; Norfenfluramine; Obesity; Paroxetine; Serotonin

1994
Distribution of fenfluramine in normal and obese mice.
    International journal of obesity, 1978, Volume: 2, Issue:1

    Topics: Adipose Tissue; Animals; Aurothioglucose; Brain; Female; Fenfluramine; Mice; Norfenfluramine; Obesity

1978
Disposition of D-fenfluramine in lean and obese rats.
    Appetite, 1988, Volume: 10, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme System; Female; Fenfluramine; Half-Life; Kinetics; Microsomes, Liver; Norfenfluramine; Obesity; Proteins; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Rats, Zucker

1988
Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Animals; Anti-Obesity Agents; Benzazepines; Cell Line; Eating; Humans; Inositol 1,4,5-Trisphosphate; Male; Obesity; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Agonists; Stereoisomerism; Structure-Activity Relationship; Weight Gain

2008