Page last updated: 2024-08-21

norfenfluramine and Heart Valve Diseases

norfenfluramine has been researched along with Heart Valve Diseases in 6 studies

*Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE). [MeSH]

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baumann, MH; Hufeisen, SJ; McBride, A; Rauser, L; Roth, BL; Rothman, RB; Savage, JE	1
Andréjak, M; Maréchaux, S; Peltier, M; Szymanski, C; Tribouilloy, C	1
Acevedo, FE; Barzilla, JE; Grande-Allen, KJ	1
Blough, B; Glennon, RA; Grande-Allen, KJ; Hufeisen, SJ; Roth, BL; Rothman, RB; Setola, V; Vesely, I	1
Dukat, M; Glennon, RA; Roth, BL; Setola, V	1
Abbaszade, I; Brown, BS; Burn, TC; Corjay, MH; Fitzgerald, LW; Hartig, PR; Hollis, GF; Hollis, JM; Largent, BL; Link, JR; Meunier, PC; Patterson, JP; Robertson, DW; Robichaud, AJ; Sun, JH; Valentine, PA	1

Reviews

1 review(s) available for norfenfluramine and Heart Valve Diseases

Article	Year
Adverse effects of benfluorex on heart valves and pulmonary circulation. Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:7 Topics: Echocardiography; Fenfluramine; Heart Valve Diseases; Heart Valves; Humans; Hypertension, Pulmonary; Hypolipidemic Agents; Norfenfluramine; Pulmonary Circulation; Randomized Controlled Trials as Topic; Receptor, Serotonin, 5-HT2B	2014

Other Studies

5 other study(ies) available for norfenfluramine and Heart Valve Diseases

Article	Year
Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. Circulation, 2000, Dec-05, Volume: 102, Issue:23 Topics: Dose-Response Relationship, Drug; Ergotamine; Fenfluramine; Heart Valve Diseases; Humans; Methylergonovine; Norfenfluramine; Receptors, Serotonin; Serotonin Antagonists	2000
Organ culture as a tool to identify early mechanisms of serotonergic valve disease. The Journal of heart valve disease, 2010, Volume: 19, Issue:5 Topics: Animals; Bioreactors; Decorin; Disease Models, Animal; Heart Valve Diseases; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Mitral Valve; Norfenfluramine; Organ Culture Techniques; Serotonin; Serotonin Agents; Swine; Versicans	2010
3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro. Molecular pharmacology, 2003, Volume: 63, Issue:6 Topics: 3,4-Methylenedioxyamphetamine; Animals; Cell Division; Cells, Cultured; COS Cells; Fenfluramine; Heart Valve Diseases; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Norfenfluramine; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Agents	2003
Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor. Molecular pharmacology, 2005, Volume: 68, Issue:1 Topics: Appetite Depressants; Cell Line; Dose-Response Relationship, Drug; Heart Valve Diseases; Humans; Imaging, Three-Dimensional; Norfenfluramine; Point Mutation; Protein Binding; Protein Structure, Secondary; Receptor, Serotonin, 5-HT2B; Serotonin	2005
Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine. Molecular pharmacology, 2000, Volume: 57, Issue:1 Topics: Animals; Appetite Depressants; Cell Line; Fenfluramine; Heart Valve Diseases; Heart Valves; Humans; Molecular Sequence Data; Norfenfluramine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA, Messenger; Serotonin Agents; Swine	2000