Page last updated: 2024-11-07

norethindrone acetate and Venous Thrombosis

norethindrone acetate has been researched along with Venous Thrombosis in 6 studies

norethisterone acetate : A 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.

Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.

Research Excerpts

ExcerptRelevanceReference
"The hazard ratio for deep vein thrombosis (2 in treated group v 1 in control group) was 2."2.77Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial. ( Eiken, P; Jensen, JE; Køber, L; Mosekilde, L; Rejnmark, L; Schierbeck, LL; Stilgren, L; Tofteng, CL, 2012)
" The aims of the present study were to evaluate a possible dose-response relationship and differential effects of different HT regimens on functionality of the APC system."2.73Differential impact of conventional and low-dose oral hormone therapy (HT), tibolone and raloxifene on functionality of the activated protein C system. ( Eilertsen, AL; Hemker, HC; Liestøl, S; Mowinckel, MC; Sandset, PM, 2007)
"However, the risk of venous thrombosis (VT) associated with OC use in women over 50 years old has never been assessed and the two preparations have not been directly compared."1.39The risk of venous thrombosis in women over 50 years old using oral contraception or postmenopausal hormone therapy. ( Cannegieter, SC; Helmerhorst, FM; Lijfering, WM; Roach, RE; Rosendaal, FR; van Hylckama Vlieg, A, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schierbeck, LL1
Rejnmark, L1
Tofteng, CL1
Stilgren, L1
Eiken, P1
Mosekilde, L1
Køber, L1
Jensen, JE1
Roach, RE1
Lijfering, WM1
Helmerhorst, FM1
Cannegieter, SC1
Rosendaal, FR1
van Hylckama Vlieg, A1
Schaudig, K1
Thomssen, C1
Eilertsen, AL1
Liestøl, S1
Mowinckel, MC2
Hemker, HC1
Sandset, PM2
Keramaris, NC1
Christodoulakos, GE1
Lambrinoudaki, IV1
Dalamanga, A1
Alexandrou, AP1
Bramis, J1
Bastounis, E1
Creatsas, GC1
Høibraaten, E1
Qvigstad, E1
Andersen, TO1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Danish Osteoporosis Prevention Study[NCT00252408]Phase 42,000 participants Interventional1990-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for norethindrone acetate and Venous Thrombosis

ArticleYear
Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial.
    BMJ (Clinical research ed.), 2012, Oct-09, Volume: 345

    Topics: Breast Neoplasms; Contraceptives, Oral, Synthetic; Denmark; Estradiol; Estrogens; Female; Follicle S

2012
Differential impact of conventional and low-dose oral hormone therapy (HT), tibolone and raloxifene on functionality of the activated protein C system.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:6

    Topics: Activated Protein C Resistance; Administration, Oral; Blood Coagulation; Dose-Response Relationship,

2007
The differential effect of estrogen, estrogen-progestin and tibolone on coagulation inhibitors in postmenopausal women.
    Climacteric : the journal of the International Menopause Society, 2007, Volume: 10, Issue:5

    Topics: Analysis of Variance; Blood Coagulation; Blood Coagulation Factors; Drug Administration Schedule; Dr

2007
The effects of hormone replacement therapy (HRT) on hemostatic variables in women with previous venous thromboembolism--results from a randomized, double-blind, clinical trial.
    Thrombosis and haemostasis, 2001, Volume: 85, Issue:5

    Topics: Biomarkers; Double-Blind Method; Drug Therapy, Combination; Estradiol; Female; Hemostasis; Hormone R

2001

Other Studies

2 other studies available for norethindrone acetate and Venous Thrombosis

ArticleYear
The risk of venous thrombosis in women over 50 years old using oral contraception or postmenopausal hormone therapy.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:1

    Topics: Administration, Cutaneous; Age Factors; Aged; Case-Control Studies; Contraceptives, Oral, Hormonal;

2013
Hormonal therapy with patch or pill: how much does it matter?
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Blood Coagulation; Drug Combinations; Estradiol; Es

2007