norethindrone acetate has been researched along with Pelvic Pain in 14 studies
norethisterone acetate : A 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.
Pelvic Pain: Pain in the pelvic region of genital and non-genital origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy and safety of ulipristal acetate (UPA) for long-term treatment of symptomatic uterine fibroids." | 9.19 | Long-term treatment of uterine fibroids with ulipristal acetate ☆. ( Barlow, DH; Bestel, E; Bouchard, P; Donnez, J; Donnez, O; Fauser, BC; Loumaye, E; Nouri, K; Osterloh, I; Palacios, S; Tomaszewski, J; Vázquez, F, 2014) |
| "To evaluate patient satisfaction at 6-months dienogest (DNG) treatment in women with symptomatic rectovaginal endometriosis who had pain persistence and were unsatisfied after 6-months of norethisterone acetate (NETA) therapy." | 9.19 | Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment. ( Ferrero, S; Morotti, M; Remorgida, V; Sozzi, F; Venturini, PL, 2014) |
| "Women with pain symptoms caused by rectovaginal endometriosis were treated with letrozole (2." | 9.15 | Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial. ( Ferrero, S; Gillott, DJ; Remorgida, V; Venturini, PL, 2011) |
| "The combination drug regimen was more effective in reducing pain and deep dyspareunia than norethisterone acetate; however, letrozole caused a higher incidence of adverse effects, cost more and did not improve patients' satisfaction or influence recurrence of pain." | 9.14 | Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis. ( Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2009) |
| "To determine the role of an aromatase inhibitor, letrozole, in the treatment of reproductive-age women with endometriosis and associated chronic pelvic pain." | 9.11 | Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. ( Ailawadi, RK; Bulun, SE; Gurates, B; Jobanputra, S; Kataria, M, 2004) |
| "To study the efficacy of long-term treatment with norethindrone acetate (NETA) in patients with rectovaginal endometriosis." | 7.85 | Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis. ( Biscaldi, E; Calanni, L; Ferrero, S; Morotti, M; Racca, A; Stabilini, C; Vellone, VG; Venturini, PL, 2017) |
| "To evaluate the efficacy and tolerability of norethindrone acetate (NA) as single-agent hormonal therapy for suppression of endometriosis symptoms in adolescents and young adults." | 7.78 | Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms. ( Berry, KF; Kaser, DJ; Laufer, MR; Missmer, SA, 2012) |
| "The administration of letrozole and norethisterone acetate reduces pain and gastrointestinal symptoms of women with colorectal endometriosis, particularly when patients suffer from symptoms mimicking diarrhoea-predominant irritable bowel syndrome." | 7.76 | Letrozole and norethisterone acetate in colorectal endometriosis. ( Biscaldi, E; Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2010) |
| "Norethindrone acetate (NETA) is a unique progestin that has both estrogenic and androgenic properties and is effective as an add-back regimen without estrogen supplementation." | 6.48 | The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis. ( Chwalisz, K; Stanczyk, FZ; Surrey, E, 2012) |
| "To investigate the efficacy and safety of ulipristal acetate (UPA) for long-term treatment of symptomatic uterine fibroids." | 5.19 | Long-term treatment of uterine fibroids with ulipristal acetate ☆. ( Barlow, DH; Bestel, E; Bouchard, P; Donnez, J; Donnez, O; Fauser, BC; Loumaye, E; Nouri, K; Osterloh, I; Palacios, S; Tomaszewski, J; Vázquez, F, 2014) |
| "To evaluate patient satisfaction at 6-months dienogest (DNG) treatment in women with symptomatic rectovaginal endometriosis who had pain persistence and were unsatisfied after 6-months of norethisterone acetate (NETA) therapy." | 5.19 | Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment. ( Ferrero, S; Morotti, M; Remorgida, V; Sozzi, F; Venturini, PL, 2014) |
| "Women with pain symptoms caused by rectovaginal endometriosis were treated with letrozole (2." | 5.15 | Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial. ( Ferrero, S; Gillott, DJ; Remorgida, V; Venturini, PL, 2011) |
| "The combination drug regimen was more effective in reducing pain and deep dyspareunia than norethisterone acetate; however, letrozole caused a higher incidence of adverse effects, cost more and did not improve patients' satisfaction or influence recurrence of pain." | 5.14 | Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis. ( Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2009) |
| "To determine the role of an aromatase inhibitor, letrozole, in the treatment of reproductive-age women with endometriosis and associated chronic pelvic pain." | 5.11 | Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. ( Ailawadi, RK; Bulun, SE; Gurates, B; Jobanputra, S; Kataria, M, 2004) |
| "This patient preference prospective study was designed to compare patients' satisfaction in women with endometriosis treated either by an extended-cycle oral contraception (OC) or by norethindrone acetate (NETA)." | 3.88 | Norethindrone acetate versus extended-cycle oral contraceptive (Seasonique ( Barra, F; Ferrero, S; Leone Roberti Maggiore, U; Scala, C; Venturini, PL, 2018) |
| "To study the efficacy of long-term treatment with norethindrone acetate (NETA) in patients with rectovaginal endometriosis." | 3.85 | Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis. ( Biscaldi, E; Calanni, L; Ferrero, S; Morotti, M; Racca, A; Stabilini, C; Vellone, VG; Venturini, PL, 2017) |
| "To evaluate the efficacy and tolerability of norethindrone acetate (NA) as single-agent hormonal therapy for suppression of endometriosis symptoms in adolescents and young adults." | 3.78 | Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms. ( Berry, KF; Kaser, DJ; Laufer, MR; Missmer, SA, 2012) |
| "The administration of letrozole and norethisterone acetate reduces pain and gastrointestinal symptoms of women with colorectal endometriosis, particularly when patients suffer from symptoms mimicking diarrhoea-predominant irritable bowel syndrome." | 3.76 | Letrozole and norethisterone acetate in colorectal endometriosis. ( Biscaldi, E; Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2010) |
| " Areas covered: This review aims to offer the reader a complete overview of pharmacokinetic (PK) and clinical efficacy of progestins for the treatment of endometriosis." | 2.58 | Current understanding on pharmacokinetics, clinical efficacy and safety of progestins for treating pain associated to endometriosis. ( Barra, F; Ferrero, S; Scala, C, 2018) |
| " Biologic data and limited clinical evidence support a potential adverse effect of long-term use of OCPs on the progression of endometriosis." | 2.55 | Progestin-only pills may be a better first-line treatment for endometriosis than combined estrogen-progestin contraceptive pills. ( Casper, RF, 2017) |
| "Norethindrone acetate (NETA) is a unique progestin that has both estrogenic and androgenic properties and is effective as an add-back regimen without estrogen supplementation." | 2.48 | The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis. ( Chwalisz, K; Stanczyk, FZ; Surrey, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 12 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morotti, M | 2 |
| Venturini, PL | 6 |
| Biscaldi, E | 2 |
| Racca, A | 1 |
| Calanni, L | 1 |
| Vellone, VG | 1 |
| Stabilini, C | 1 |
| Ferrero, S | 7 |
| Vercellini, P | 1 |
| Ottolini, F | 1 |
| Frattaruolo, MP | 1 |
| Buggio, L | 1 |
| Roberto, A | 1 |
| Somigliana, E | 1 |
| Scala, C | 2 |
| Leone Roberti Maggiore, U | 1 |
| Barra, F | 2 |
| Donnez, J | 1 |
| Vázquez, F | 1 |
| Tomaszewski, J | 1 |
| Nouri, K | 1 |
| Bouchard, P | 1 |
| Fauser, BC | 1 |
| Barlow, DH | 1 |
| Palacios, S | 1 |
| Donnez, O | 1 |
| Bestel, E | 1 |
| Osterloh, I | 1 |
| Loumaye, E | 1 |
| Sozzi, F | 1 |
| Remorgida, V | 4 |
| Agarwal, SK | 1 |
| Foster, WG | 1 |
| Casper, RF | 1 |
| Camerini, G | 2 |
| Seracchioli, R | 2 |
| Ragni, N | 2 |
| Gillott, DJ | 1 |
| Kaser, DJ | 1 |
| Missmer, SA | 1 |
| Berry, KF | 1 |
| Laufer, MR | 1 |
| Chwalisz, K | 1 |
| Surrey, E | 1 |
| Stanczyk, FZ | 1 |
| Ailawadi, RK | 1 |
| Jobanputra, S | 1 |
| Kataria, M | 1 |
| Gurates, B | 1 |
| Bulun, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase III, Multicentre, Clinical Study Investigating the Efficacy and Safety of 3-months Open-label Treatment With PGL4001, Followed by a Randomised, Double-blind Placebo Controlled Period of 10 Days Treatment With Progestin, in Subjects With Myomas and[NCT01156857] | Phase 3 | 209 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| A Phase III, Multicentre, Clinical Study Investigating the Efficacy and Safety of Three Successive Periods of 3-month Open-label PGL4001 Treatment, Each Followed by Ten Days of Double-blind Treatment With Progestin or Placebo and a Drug-free Period Until [NCT01252069] | Phase 3 | 132 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for norethindrone acetate and Pelvic Pain
| Article | Year |
|---|---|
Current understanding on pharmacokinetics, clinical efficacy and safety of progestins for treating pain associated to endometriosis.
Topics: Administration, Oral; Endometriosis; Female; Humans; Medroxyprogesterone Acetate; Norethindrone; Nor | 2018 |
Progestin-only pills may be a better first-line treatment for endometriosis than combined estrogen-progestin contraceptive pills.
Topics: Administration, Oral; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Endometriosis; | 2017 |
The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis.
Topics: Bone Density; Endometriosis; Estrogens; Female; Gonadotropin-Releasing Hormone; Hot Flashes; Humans; | 2012 |
6 trials available for norethindrone acetate and Pelvic Pain
| Article | Year |
|---|---|
Long-term treatment of uterine fibroids with ulipristal acetate ☆.
Topics: Administration, Oral; Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch | 2014 |
Long-term treatment of uterine fibroids with ulipristal acetate ☆.
Topics: Administration, Oral; Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch | 2014 |
Long-term treatment of uterine fibroids with ulipristal acetate ☆.
Topics: Administration, Oral; Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch | 2014 |
Long-term treatment of uterine fibroids with ulipristal acetate ☆.
Topics: Administration, Oral; Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch | 2014 |
Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment.
Topics: Adult; Contraceptives, Oral; Endometriosis; Female; Follow-Up Studies; Humans; Nandrolone; Norethind | 2014 |
Reduction in Endometrioma Size with Three Months of Aromatase Inhibition and Progestin Add-Back.
Topics: Adult; Aromatase Inhibitors; Cohort Studies; Drug Therapy, Combination; Endometriosis; Female; Human | 2015 |
Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis.
Topics: Adult; Analgesics, Non-Narcotic; Aromatase Inhibitors; Drug Therapy, Combination; Dysmenorrhea; Dysp | 2009 |
Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial.
Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Dyspareunia; Endometriosis; Female; Humans; | 2011 |
Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study.
Topics: Adult; Analysis of Variance; Aromatase Inhibitors; Bone Density; Contraceptives, Oral, Synthetic; En | 2004 |
5 other studies available for norethindrone acetate and Pelvic Pain
| Article | Year |
|---|---|
Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis.
Topics: Adult; Cohort Studies; Dyspareunia; Endometriosis; Female; Humans; Norethindrone; Norethindrone Acet | 2017 |
Is Shifting to a Progestin Worthwhile When Estrogen-Progestins Are Inefficacious for Endometriosis-Associated Pain?
Topics: Adolescent; Adult; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Desogestrel; Endometriosis | 2018 |
Norethindrone acetate versus extended-cycle oral contraceptive (Seasonique
Topics: Adult; Contraceptives, Oral, Synthetic; Drug Combinations; Endometriosis; Ethinyl Estradiol; Female; | 2018 |
Letrozole and norethisterone acetate in colorectal endometriosis.
Topics: Abdominal Pain; Aromatase Inhibitors; Colonic Diseases; Diarrhea; Drug Therapy, Combination; Dyspare | 2010 |
Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms.
Topics: Adolescent; Adult; Contraceptives, Oral, Synthetic; Endometriosis; Female; Humans; Metrorrhagia; Nor | 2012 |