Page last updated: 2024-11-07

norethindrone acetate and Osteoporosis, Postmenopausal

norethindrone acetate has been researched along with Osteoporosis, Postmenopausal in 21 studies

norethisterone acetate : A 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.

Osteoporosis, Postmenopausal: Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.

Research Excerpts

ExcerptRelevanceReference
"Alendronate has no effect on vascular markers or sex hormone-binding globulin."2.71Effects of hormone therapy and alendronate on C-reactive protein, E-selectin, and sex hormone-binding globulin in osteoporotic women. ( Eviö, S; Tiitinen, A; Välimäki, M; Ylikorkala, O, 2003)
"Genistein treatment significantly reduced the excretion of pyridinium cross-links at 6 months (PYR = -54 +/- 10%; DPYR = -55 +/- 13%; p < 0."2.70Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study. ( Altavilla, D; Cincotta, M; Corrado, F; Crisafulli, A; D'Anna, R; Frisina, N; Gaudio, A; Ientile, R; Lasco, A; Morabito, N; Pizzoleo, MA; Squadrito, F; Vergara, C, 2002)
" Serum CrossLaps decreased by about 50% in the levormeloxifene groups, with no dose-response effect."2.70Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy. ( Alexandersen, P; Christiansen, C; Delmas, PD; Riis, BJ; Stakkestad, JA, 2001)
"In a blinded, prospective, dose-response pilot study of continuous estrogen-progestin replacement therapy, 77 thin, nonsmoking, white women, who were 12 to 60 months postmenopausal and had normal medical histories, were randomly assigned to receive one of five dose combinations of daily ethinyl estradiol and norethindrone acetate (20 micrograms and 1."2.67A study of combined continuous ethinyl estradiol and norethindrone acetate for postmenopausal hormone replacement. ( Frenchek, B; Speroff, L; Speroff, T; Williams, SR, 1990)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's6 (28.57)18.2507
2000's11 (52.38)29.6817
2010's1 (4.76)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Costa-Paiva, L1
O Wender, MC1
Machado, RB1
Pompei, LM1
Nahas, EA1
Nahas-Neto, J1
Del Debbio, SY1
Badalotti, M1
Cruz, AM1
Tuppurainen, M1
Härmä, K1
Komulainen, M1
Kiviniemi, V1
Kröger, H1
Honkanen, R1
Alhava, E1
Jurvelin, J1
Saarikoski, S1
Posaci, C1
Altunyurt, S1
Islekel, H1
Saygili, U1
Altekin, E1
Onvural, A1
Onvural, B1
Jamin, C1
Poncelet, C1
Madelenat, P1
Morabito, N1
Crisafulli, A1
Vergara, C1
Gaudio, A1
Lasco, A1
Frisina, N1
D'Anna, R1
Corrado, F1
Pizzoleo, MA1
Cincotta, M1
Altavilla, D1
Ientile, R1
Squadrito, F1
Ylikorkala, O2
Eviö, S2
Välimäki, M1
Tiitinen, A2
Popp, AW1
Bodmer, C1
Senn, C1
Fuchs, G1
Kraenzlin, ME1
Wyss, H1
Birkhaeuser, MH1
Lippuner, K1
Tarkkila, L1
Sorsa, T1
Furuholm, J1
Välimäki, MJ1
Meurman, JH1
Yüksel, H1
Odabaşi, AR1
Demircan, S1
Karul, A1
Kozaci, LD1
Köseoğlu, K1
Kizilkaya, K1
Başak, O1
Boone, RH1
Cheung, AM1
Girlan, LM1
Heathcote, EJ1
Gambacciani, M1
Cappagli, B1
Ciaponi, M1
Pepe, A1
Vacca, F1
Genazzani, AR1
Stevenson, JC1
Hillard, TC1
Lees, B1
Whitcroft, SI1
Ellerington, MC1
Whitehead, MI1
Cubrilo-Turek, M1
Stavljenić-Rukavina, A1
Turek, S1
Kusec, V1
Duraković, Z1
Vestergaard, P1
Hermann, AP1
Orskov, H1
Mosekilde, L1
van Hoof, HJ1
van der Mooren, MJ1
Swinkels, LM1
Sweep, CG1
Merkus, JM1
Benraad, TJ1
Alexandersen, P1
Riis, BJ1
Stakkestad, JA1
Delmas, PD1
Christiansen, C1
Loh, FH1
Chen, LH1
Yu, SL1
Jorgensen, LN1
Williams, SR1
Frenchek, B1
Speroff, T1
Speroff, L1
Resch, H2
Pietschmann, P2
Krexner, E1
Woloszczuk, W1
Willvonseder, R2
Dören, M1
Montag, M1
Schneider, HP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Clinical Trial on the Effectts of Estradiol 2 mg + NETA 1 mg With or Without Clodronate on Bone Mineral Density and Bone Markers of Osteoporotic Postmenopausal 167 Finnish Women.[NCT00877097]167 participants (Actual)Interventional1996-07-31Completed
Genistein Use in Postmenopausal Women With Metabolic Syndrome[NCT00541710]Phase 2/Phase 3120 participants (Actual)Interventional2007-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for norethindrone acetate and Osteoporosis, Postmenopausal

ArticleYear
[Tibolone].
    Presse medicale (Paris, France : 1983), 2002, Sep-07, Volume: 31, Issue:28

    Topics: Adult; Aged; Animals; Blood Coagulation; Breast; Cardiovascular Diseases; Controlled Clinical Trials

2002

Trials

16 trials available for norethindrone acetate and Osteoporosis, Postmenopausal

ArticleYear
Effects of ultra-low dose hormone therapy on biochemical bone turnover markers in postmenopausal women: A randomized, placebo-controlled, double-blind trial.
    Post reproductive health, 2022, Volume: 28, Issue:3

    Topics: Alkaline Phosphatase; Biomarkers; Bone Density; Bone Remodeling; Bone Resorption; Collagen Type I; D

2022
Effects of continuous combined hormone replacement therapy and clodronate on bone mineral density in osteoporotic postmenopausal women: a 5-year follow-up.
    Maturitas, 2010, Volume: 66, Issue:4

    Topics: Alkaline Phosphatase; Bone Density; Bone Density Conservation Agents; Clodronic Acid; Drug Therapy,

2010
Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:10

    Topics: Alkaline Phosphatase; Amino Acids; Bone Density; Combined Modality Therapy; Diet, Fat-Restricted; Do

2002
Effects of hormone therapy and alendronate on C-reactive protein, E-selectin, and sex hormone-binding globulin in osteoporotic women.
    Fertility and sterility, 2003, Volume: 80, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alendronate; C-Reactive Protein; Double-Blind Method;

2003
Prevention of postmenopausal bone loss with long-cycle hormone replacement therapy.
    Maturitas, 2006, Jan-20, Volume: 53, Issue:2

    Topics: Body Mass Index; Bone Density; Endometrial Hyperplasia; Endometrium; Estradiol; Estrogen Replacement

2006
Effects of alendronate and hormone replacement therapy, alone and in combination, on saliva, periodontal conditions and gingival crevicular fluid matrix metalloproteinase-8 levels in women with osteoporosis.
    Oral diseases, 2006, Volume: 12, Issue:2

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density; Bone Density Conservation Agents; Double-Blind M

2006
Effects of oral continuous 17beta-estradiol plus norethisterone acetate replacement therapy on abdominal subcutaneous fat, serum leptin levels and body composition.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2006, Volume: 22, Issue:7

    Topics: Administration, Oral; Adult; Aged; Body Composition; Body Mass Index; Body Weight; Double-Blind Meth

2006
Osteoporosis in primary biliary cirrhosis: a randomized trial of the efficacy and feasibility of estrogen/progestin.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:6

    Topics: Administration, Cutaneous; Bilirubin; Bone Density; Double-Blind Method; Estradiol; Estrogen Replace

2006
Ultra low-dose hormone replacement therapy and bone protection in postmenopausal women.
    Maturitas, 2008, Jan-20, Volume: 59, Issue:1

    Topics: Bone Density; Bone Density Conservation Agents; Calcium, Dietary; Contraceptives, Oral, Synthetic; D

2008
Postmenopausal bone loss: does HRT always work?
    International journal of fertility and menopausal studies, 1993, Volume: 38 Suppl 2

    Topics: Administration, Cutaneous; Administration, Oral; Alkaline Phosphatase; Bone Density; Calcium; Creati

1993
Effect of sex hormone replacement on the insulin-like growth factor system and bone mineral: a cross-sectional and longitudinal study in 595 perimenopausal women participating in the Danish Osteoporosis Prevention Study.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:7

    Topics: Bone Density; Cross-Sectional Studies; Denmark; Estradiol; Estrogen Replacement Therapy; Female; Hum

1999
Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:2

    Topics: Bone Density; Calcium; Cholesterol; Double-Blind Method; Endometrium; Estradiol; Estrogen Replacemen

2001
The efficacy of two dosages of a continuous combined hormone replacement regimen.
    Maturitas, 2002, Feb-26, Volume: 41, Issue:2

    Topics: Aged; Alkaline Phosphatase; Amino Acids; Asian People; Cholesterol; Cholesterol, HDL; Cholesterol, L

2002
A study of combined continuous ethinyl estradiol and norethindrone acetate for postmenopausal hormone replacement.
    American journal of obstetrics and gynecology, 1990, Volume: 162, Issue:2

    Topics: Adult; Biopsy; Bone Density; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; D

1990
Estimated long-term effect of calcitonin treatment in acute osteoporotic spine fractures.
    Calcified tissue international, 1989, Volume: 45, Issue:4

    Topics: Aged; Bone and Bones; Calcitonin; Calcium; Estradiol; Female; Fractures, Spontaneous; Humans; Middle

1989
[Prospective perimenopausal estrogen-progestin substitution therapies for the prevention of osteoporosis].
    Archives of gynecology and obstetrics, 1989, Volume: 245, Issue:1-4

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Estradiol; Estriol; Female; Humans; Medroxyprog

1989

Other Studies

4 other studies available for norethindrone acetate and Osteoporosis, Postmenopausal

ArticleYear
The values of urinary NTx in postmenopausal women undergoing HRT; the role of additional alendronate therapy.
    Maturitas, 2002, Aug-30, Volume: 42, Issue:4

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Alendronate; Bone Density; Collagen; Collage

2002
The usefulness of biochemical bone markers in predicting the response of hormone replacement therapy in perimenopausal cigarette smoking healthy women.
    Collegium antropologicum, 1999, Volume: 23, Issue:1

    Topics: Alkaline Phosphatase; Biomarkers; Calcium; Collagen; Collagen Type I; Estradiol; Estrogen Replacemen

1999
Female sex hormone replacement therapy increases serum free 1,25-dihydroxyvitamin D3: a 1-year prospective study.
    Clinical endocrinology, 1999, Volume: 50, Issue:4

    Topics: Calcitriol; Drug Therapy, Combination; Estradiol; Estrogen Replacement Therapy; Female; Humans; Midd

1999
Effects of one-year hormone replacement therapy on peripheral bone mineral content in patients with osteoporotic spine fractures.
    Acta endocrinologica, 1990, Volume: 123, Issue:1

    Topics: Alkaline Phosphatase; Bone and Bones; Double-Blind Method; Drug Therapy, Combination; Estradiol; Est

1990