Page last updated: 2024-11-07

norethindrone acetate and Endometrioma

norethindrone acetate has been researched along with Endometrioma in 37 studies

norethisterone acetate : A 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.

Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.

Research Excerpts

ExcerptRelevanceReference
"To evaluate patient satisfaction at 6-months dienogest (DNG) treatment in women with symptomatic rectovaginal endometriosis who had pain persistence and were unsatisfied after 6-months of norethisterone acetate (NETA) therapy."9.19Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment. ( Ferrero, S; Morotti, M; Remorgida, V; Sozzi, F; Venturini, PL, 2014)
"Women with pain symptoms caused by rectovaginal endometriosis were treated with letrozole (2."9.15Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial. ( Ferrero, S; Gillott, DJ; Remorgida, V; Venturini, PL, 2011)
"The combination drug regimen was more effective in reducing pain and deep dyspareunia than norethisterone acetate; however, letrozole caused a higher incidence of adverse effects, cost more and did not improve patients' satisfaction or influence recurrence of pain."9.14Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis. ( Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2009)
"To evaluate the efficacy, safety, and tolerability of an estrogen-progestogen combination versus low-dose norethindrone acetate in the treatment of persistent pain after surgery for symptomatic rectovaginal endometriosis."9.11Treatment of symptomatic rectovaginal endometriosis with an estrogen-progestogen combination versus low-dose norethindrone acetate. ( Chiodini, A; Crosignani, PG; De Giorgi, O; Pasin, R; Pietropaolo, G; Vercellini, P, 2005)
"To determine the role of an aromatase inhibitor, letrozole, in the treatment of reproductive-age women with endometriosis and associated chronic pelvic pain."9.11Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. ( Ailawadi, RK; Bulun, SE; Gurates, B; Jobanputra, S; Kataria, M, 2004)
"Goserelin diminished significantly the symptoms and laparoscopic scores of endometriosis."9.08Comparison of the gonadotropin-releasing hormone agonist goserelin acetate alone versus goserelin combined with estrogen-progestogen add-back therapy in the treatment of endometriosis. ( Hagman, E; Kiilholma, P; Kivinen, S; Korhonen, M; Tuimala, R, 1995)
"To study the efficacy of long-term treatment with norethindrone acetate (NETA) in patients with rectovaginal endometriosis."7.85Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis. ( Biscaldi, E; Calanni, L; Ferrero, S; Morotti, M; Racca, A; Stabilini, C; Vellone, VG; Venturini, PL, 2017)
"NET-A in a dose greater than 10 mg/d might be associated with increased risk for hepatic adenomas, likely due to peripheral conversion to ethinyl estradiol."7.85Hepatic Adenomas in Adolescents and Young Women with Endometriosis Treated with Norethindrone Acetate. ( Brady, PC; Laufer, MR; Missmer, SA, 2017)
"To assess the proportion of patients satisfied with their treatment before and after a systematic change from norethindrone acetate to dienogest as the first-line progestin for symptomatic endometriosis."7.83Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis: a before and after study. ( Alberico, D; Bracco, B; Dhouha, D; Mosconi, P; Roberto, A; Somigliana, E; Vercellini, P, 2016)
"To evaluate the efficacy and tolerability of norethindrone acetate (NA) as single-agent hormonal therapy for suppression of endometriosis symptoms in adolescents and young adults."7.78Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms. ( Berry, KF; Kaser, DJ; Laufer, MR; Missmer, SA, 2012)
"The administration of letrozole and norethisterone acetate reduces pain and gastrointestinal symptoms of women with colorectal endometriosis, particularly when patients suffer from symptoms mimicking diarrhoea-predominant irritable bowel syndrome."7.76Letrozole and norethisterone acetate in colorectal endometriosis. ( Biscaldi, E; Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2010)
"Norethindrone acetate (NETA) is a unique progestin that has both estrogenic and androgenic properties and is effective as an add-back regimen without estrogen supplementation."6.48The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis. ( Chwalisz, K; Stanczyk, FZ; Surrey, E, 2012)
"Endometriosis affects over 10 million women in the United States."5.43Analysis of Adherence, Persistence, and Surgery Among Endometriosis Patients Treated with Leuprolide Acetate Plus Norethindrone Acetate Add-Back Therapy. ( Bonafede, M; Castelli-Haley, J; Farr, AM; Soliman, AM; Winkel, C, 2016)
"To assess whether add-back therapy with norethindrone acetate or norethindrone acetate plus conjugated equine estrogens is superior to maintain bone health in adolescents and young women using gonadotropin-releasing hormone agonists for endometriosis."5.20Hormonal Add-Back Therapy for Females Treated With Gonadotropin-Releasing Hormone Agonist for Endometriosis: A Randomized Controlled Trial. ( DiVasta, AD; Feldman, HA; Gordon, CM; Hornstein, MD; Laufer, MR; Sadler Gallagher, J; Stokes, NA, 2015)
"To evaluate patient satisfaction at 6-months dienogest (DNG) treatment in women with symptomatic rectovaginal endometriosis who had pain persistence and were unsatisfied after 6-months of norethisterone acetate (NETA) therapy."5.19Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment. ( Ferrero, S; Morotti, M; Remorgida, V; Sozzi, F; Venturini, PL, 2014)
"Women with pain symptoms caused by rectovaginal endometriosis were treated with letrozole (2."5.15Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial. ( Ferrero, S; Gillott, DJ; Remorgida, V; Venturini, PL, 2011)
"The combination drug regimen was more effective in reducing pain and deep dyspareunia than norethisterone acetate; however, letrozole caused a higher incidence of adverse effects, cost more and did not improve patients' satisfaction or influence recurrence of pain."5.14Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis. ( Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2009)
"To evaluate the efficacy, safety, and tolerability of an estrogen-progestogen combination versus low-dose norethindrone acetate in the treatment of persistent pain after surgery for symptomatic rectovaginal endometriosis."5.11Treatment of symptomatic rectovaginal endometriosis with an estrogen-progestogen combination versus low-dose norethindrone acetate. ( Chiodini, A; Crosignani, PG; De Giorgi, O; Pasin, R; Pietropaolo, G; Vercellini, P, 2005)
"To determine the role of an aromatase inhibitor, letrozole, in the treatment of reproductive-age women with endometriosis and associated chronic pelvic pain."5.11Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. ( Ailawadi, RK; Bulun, SE; Gurates, B; Jobanputra, S; Kataria, M, 2004)
"GnRH agonist and norethindrone acetate alone or combined with low-dose conjugated equine estrogens administered to symptomatic endometriosis patients for 12 months provides extended pain relief and bone mineral density preservation after completion of therapy."5.10Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up. ( Hornstein, MD; Surrey, ES, 2002)
"Goserelin diminished significantly the symptoms and laparoscopic scores of endometriosis."5.08Comparison of the gonadotropin-releasing hormone agonist goserelin acetate alone versus goserelin combined with estrogen-progestogen add-back therapy in the treatment of endometriosis. ( Hagman, E; Kiilholma, P; Kivinen, S; Korhonen, M; Tuimala, R, 1995)
"This patient preference prospective study was designed to compare patients' satisfaction in women with endometriosis treated either by an extended-cycle oral contraception (OC) or by norethindrone acetate (NETA)."3.88Norethindrone acetate versus extended-cycle oral contraceptive (Seasonique ( Barra, F; Ferrero, S; Leone Roberti Maggiore, U; Scala, C; Venturini, PL, 2018)
"NET-A in a dose greater than 10 mg/d might be associated with increased risk for hepatic adenomas, likely due to peripheral conversion to ethinyl estradiol."3.85Hepatic Adenomas in Adolescents and Young Women with Endometriosis Treated with Norethindrone Acetate. ( Brady, PC; Laufer, MR; Missmer, SA, 2017)
"To study the efficacy of long-term treatment with norethindrone acetate (NETA) in patients with rectovaginal endometriosis."3.85Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis. ( Biscaldi, E; Calanni, L; Ferrero, S; Morotti, M; Racca, A; Stabilini, C; Vellone, VG; Venturini, PL, 2017)
"To assess the proportion of patients satisfied with their treatment before and after a systematic change from norethindrone acetate to dienogest as the first-line progestin for symptomatic endometriosis."3.83Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis: a before and after study. ( Alberico, D; Bracco, B; Dhouha, D; Mosconi, P; Roberto, A; Somigliana, E; Vercellini, P, 2016)
"To compare the efficacy of norethisterone acetate (NETA; group N) or letrozole combined with NETA (group L) in treating endometriotic ovarian cysts."3.80Norethisterone acetate versus norethisterone acetate combined with letrozole for the treatment of ovarian endometriotic cysts: a patient preference study. ( Ferrero, S; Leone Roberti Maggiore, U; Remorgida, V; Venturini, PL, 2014)
"To evaluate the efficacy and tolerability of norethindrone acetate (NA) as single-agent hormonal therapy for suppression of endometriosis symptoms in adolescents and young adults."3.78Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms. ( Berry, KF; Kaser, DJ; Laufer, MR; Missmer, SA, 2012)
"The administration of letrozole and norethisterone acetate reduces pain and gastrointestinal symptoms of women with colorectal endometriosis, particularly when patients suffer from symptoms mimicking diarrhoea-predominant irritable bowel syndrome."3.76Letrozole and norethisterone acetate in colorectal endometriosis. ( Biscaldi, E; Camerini, G; Ferrero, S; Ragni, N; Remorgida, V; Seracchioli, R; Venturini, PL, 2010)
"BMD at the hip was normal in most adolescents with endometriosis who were receiving a GnRH-agonist plus add-back therapy with norethindrone acetate."3.74Bone density in adolescents treated with a GnRH agonist and add-back therapy for endometriosis. ( Divasta, AD; Gordon, CM; Laufer, MR, 2007)
" Treatment with GnRHa combined with add-back therapy led to improved QOL, with no worsening of mood or menopausal side effects."2.84The Effects of Gonadotropin-Releasing Hormone Agonist Combined with Add-Back Therapy on Quality of Life for Adolescents with Endometriosis: A Randomized Controlled Trial. ( DiVasta, AD; Feldman, HA; Gordon, CM; Hornstein, MD; Laufer, MR; Sadler Gallagher, J; Stokes, NA, 2017)
"Endometriosis is a chronic estrogen and progestogen responsive inflammatory disease associated with pain symptoms and infertility."2.58Current understanding on pharmacokinetics, clinical efficacy and safety of progestins for treating pain associated to endometriosis. ( Barra, F; Ferrero, S; Scala, C, 2018)
" Biologic data and limited clinical evidence support a potential adverse effect of long-term use of OCPs on the progression of endometriosis."2.55Progestin-only pills may be a better first-line treatment for endometriosis than combined estrogen-progestin contraceptive pills. ( Casper, RF, 2017)
"Norethindrone acetate (NETA) is a unique progestin that has both estrogenic and androgenic properties and is effective as an add-back regimen without estrogen supplementation."2.48The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis. ( Chwalisz, K; Stanczyk, FZ; Surrey, E, 2012)
" With further investigation, such regimens may allow safe prolongation of GnRH analogue use without sacrificing efficacy in those endometriosis patients with severe pelvic pain."2.40Add-back therapy: extending safety and efficacy of GnRH analogues in the gynecologic patient. ( Surrey, ES, 1998)
"Progestins are first-line, on-label treatments of endometriosis that may have direct effects on endometriotic lesions through these nuclear receptors."1.46The association between progestins, nuclear receptors expression and inflammation in endometrial stromal cells from women with endometriosis. ( Bersinger, NA; Facchinetti, F; Grandi, G; McKinnon, BD; Mueller, MD, 2017)
"Endometriosis is an estrogen-dependent inflammatory disease."1.43Progestin suppressed inflammation and cell viability of tumor necrosis factor-α-stimulated endometriotic stromal cells. ( Bersinger, N; Cagnacci, A; Grandi, G; McKinnon, B; Mueller, M; Nirgianakis, K; Papadia, A, 2016)
"Endometriosis affects over 10 million women in the United States."1.43Analysis of Adherence, Persistence, and Surgery Among Endometriosis Patients Treated with Leuprolide Acetate Plus Norethindrone Acetate Add-Back Therapy. ( Bonafede, M; Castelli-Haley, J; Farr, AM; Soliman, AM; Winkel, C, 2016)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (10.81)18.2507
2000's6 (16.22)29.6817
2010's27 (72.97)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morotti, M2
Venturini, PL9
Biscaldi, E3
Racca, A1
Calanni, L1
Vellone, VG1
Stabilini, C1
Ferrero, S11
Grandi, G2
Mueller, MD1
Bersinger, NA1
Facchinetti, F1
McKinnon, BD1
Vercellini, P6
Ottolini, F2
Frattaruolo, MP4
Buggio, L2
Roberto, A3
Somigliana, E5
Scala, C3
Leone Roberti Maggiore, U3
Barra, F2
Jones, GL1
Consonni, D2
Alberico, D2
Fedele, L2
Remorgida, V8
Sozzi, F1
DiVasta, AD3
Feldman, HA2
Sadler Gallagher, J2
Stokes, NA2
Laufer, MR5
Hornstein, MD3
Gordon, CM3
Agarwal, SK1
Foster, WG1
Bracco, B1
Mosconi, P1
Dhouha, D1
Soliman, AM1
Bonafede, M1
Farr, AM1
Castelli-Haley, J1
Winkel, C1
Mueller, M1
Bersinger, N1
Papadia, A1
Nirgianakis, K1
Cagnacci, A1
McKinnon, B1
Brady, PC1
Missmer, SA2
Casper, RF1
Camerini, G3
Seracchioli, R2
Ragni, N3
Fuldeore, MJ1
Marx, SE1
Chwalisz, K2
Smeeding, JE1
Brook, RA1
Roman, H1
Gillott, DJ1
Kaser, DJ1
Berry, KF1
Surrey, E1
Stanczyk, FZ1
De Giorgi, O2
Di Luca, M1
Ailawadi, RK1
Jobanputra, S1
Kataria, M1
Gurates, B1
Bulun, SE1
Pietropaolo, G1
Pasin, R1
Chiodini, A1
Crosignani, PG1
Kiilholma, P1
Tuimala, R1
Kivinen, S1
Korhonen, M1
Hagman, E1
Edmonds, DK1
Marik, JJ1
Surrey, ES2
Pierce, SJ1
Gazvani, MR1
Farquharson, RG1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assisted Reproductive Technology (ART) and Pregnancy Outcomes in Women With Adenomyosis (Internal Endometriosis) According to Stimulation Protocol in Relation to Immunological and Endometrial Features: a Prospective, Randomized Study[NCT05937490]Phase 4500 participants (Anticipated)Interventional2023-03-27Recruiting
The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial[NCT00474851]Phase 253 participants (Actual)Interventional2007-08-31Completed
Effects of the Supplementation of α-lipoic Acid (ALA), Magnesium, Vitamin B6 and Vitamin D to Women Presenting Risk Factor for Pre-term Birth[NCT03952533]122 participants (Actual)Interventional2019-05-05Completed
A Randomized Controlled Trial of a Nutritional Intervention for Endometriosis[NCT05175248]120 participants (Anticipated)Interventional2022-03-02Recruiting
Pilot Study of the IL-1 Antagonist Anakinra for the Treatment of Endometriosis Related Symptoms[NCT03991520]Early Phase 120 participants (Anticipated)Interventional2020-06-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Bone Mineral Density

Adjusted mean change in total body areal bone mineral density (aBMD) over the 12 month trial (NCT00474851)
Timeframe: Baseline to 12 months

Interventiong/cm^2 (Mean)
Intervention Group0.01
Placebo Group-0.11

Total Body Bone Mineral Content (BMC)

(NCT00474851)
Timeframe: Baseline to 12 months

Interventiong (Mean)
Intervention Group37
Placebo Group15

Reviews

4 reviews available for norethindrone acetate and Endometrioma

ArticleYear
Current understanding on pharmacokinetics, clinical efficacy and safety of progestins for treating pain associated to endometriosis.
    Expert opinion on drug metabolism & toxicology, 2018, Volume: 14, Issue:4

    Topics: Administration, Oral; Endometriosis; Female; Humans; Medroxyprogesterone Acetate; Norethindrone; Nor

2018
Progestin-only pills may be a better first-line treatment for endometriosis than combined estrogen-progestin contraceptive pills.
    Fertility and sterility, 2017, Volume: 107, Issue:3

    Topics: Administration, Oral; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Endometriosis;

2017
The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis.
    Reproductive sciences (Thousand Oaks, Calif.), 2012, Volume: 19, Issue:6

    Topics: Bone Density; Endometriosis; Estrogens; Female; Gonadotropin-Releasing Hormone; Hot Flashes; Humans;

2012
Add-back therapy: extending safety and efficacy of GnRH analogues in the gynecologic patient.
    Gynecologic and obstetric investigation, 1998, Volume: 45 Suppl 1

    Topics: Endometriosis; Estrogens; Estrogens, Conjugated (USP); Female; Genital Diseases, Female; Gonadotropi

1998

Trials

14 trials available for norethindrone acetate and Endometrioma

ArticleYear
Dienogest in women with persistent endometriosis-related pelvic pain during norethisterone acetate treatment.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 183

    Topics: Adult; Contraceptives, Oral; Endometriosis; Female; Follow-Up Studies; Humans; Nandrolone; Norethind

2014
Hormonal Add-Back Therapy for Females Treated With Gonadotropin-Releasing Hormone Agonist for Endometriosis: A Randomized Controlled Trial.
    Obstetrics and gynecology, 2015, Volume: 126, Issue:3

    Topics: Absorptiometry, Photon; Adolescent; Bone Density; Bone Resorption; Dose-Response Relationship, Drug;

2015
Reduction in Endometrioma Size with Three Months of Aromatase Inhibition and Progestin Add-Back.
    BioMed research international, 2015, Volume: 2015

    Topics: Adult; Aromatase Inhibitors; Cohort Studies; Drug Therapy, Combination; Endometriosis; Female; Human

2015
The Effects of Gonadotropin-Releasing Hormone Agonist Combined with Add-Back Therapy on Quality of Life for Adolescents with Endometriosis: A Randomized Controlled Trial.
    Journal of pediatric and adolescent gynecology, 2017, Volume: 30, Issue:2

    Topics: Adolescent; Boston; Contraceptives, Oral, Synthetic; Double-Blind Method; Drug Therapy, Combination;

2017
Letrozole combined with norethisterone acetate compared with norethisterone acetate alone in the treatment of pain symptoms caused by endometriosis.
    Human reproduction (Oxford, England), 2009, Volume: 24, Issue:12

    Topics: Adult; Analgesics, Non-Narcotic; Aromatase Inhibitors; Drug Therapy, Combination; Dysmenorrhea; Dysp

2009
Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Dyspareunia; Endometriosis; Female; Humans;

2011
Surgical versus medical treatment for endometriosis-associated severe deep dyspareunia: I. Effect on pain during intercourse and patient satisfaction.
    Human reproduction (Oxford, England), 2012, Volume: 27, Issue:12

    Topics: Adult; Body Mass Index; Cohort Studies; Coitus; Dyspareunia; Endometriosis; Female; Humans; Logistic

2012
Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies.
    Archives of gynecology and obstetrics, 2013, Volume: 287, Issue:3

    Topics: Adult; Aromatase Inhibitors; Calcium; Cholecalciferol; Contraceptives, Oral, Sequential; Contracepti

2013
Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study.
    Fertility and sterility, 2004, Volume: 81, Issue:2

    Topics: Adult; Analysis of Variance; Aromatase Inhibitors; Bone Density; Contraceptives, Oral, Synthetic; En

2004
Treatment of symptomatic rectovaginal endometriosis with an estrogen-progestogen combination versus low-dose norethindrone acetate.
    Fertility and sterility, 2005, Volume: 84, Issue:5

    Topics: Adolescent; Adult; Confidence Intervals; Drug Therapy, Combination; Endometriosis; Estrogen Replacem

2005
Comparison of the gonadotropin-releasing hormone agonist goserelin acetate alone versus goserelin combined with estrogen-progestogen add-back therapy in the treatment of endometriosis.
    Fertility and sterility, 1995, Volume: 64, Issue:5

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Endometrios

1995
Add-back therapy in the treatment of endometriosis: the European experience.
    British journal of obstetrics and gynaecology, 1996, Volume: 103 Suppl 14

    Topics: Administration, Cutaneous; Bone Density; Double-Blind Method; Drug Combinations; Endometriosis; Estr

1996
Long-term use of gonadotropin-releasing hormone analogs and hormone replacement therapy in the management of endometriosis: a randomized trial with a 6-year follow-up.
    Fertility and sterility, 2000, Volume: 74, Issue:5

    Topics: Adult; Bone Density; Drug Implants; Drug Therapy, Combination; Endometriosis; Estradiol; Female; Fol

2000
Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up.
    Obstetrics and gynecology, 2002, Volume: 99, Issue:5 Pt 1

    Topics: Adult; Bone Density; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule;

2002

Other Studies

19 other studies available for norethindrone acetate and Endometrioma

ArticleYear
Efficacy and acceptability of long-term norethindrone acetate for the treatment of rectovaginal endometriosis.
    European journal of obstetrics, gynecology, and reproductive biology, 2017, Volume: 213

    Topics: Adult; Cohort Studies; Dyspareunia; Endometriosis; Female; Humans; Norethindrone; Norethindrone Acet

2017
The association between progestins, nuclear receptors expression and inflammation in endometrial stromal cells from women with endometriosis.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2017, Volume: 33, Issue:9

    Topics: Adult; Cytokines; Endometriosis; Endometrium; Female; Humans; Inflammation; Medroxyprogesterone Acet

2017
Is Shifting to a Progestin Worthwhile When Estrogen-Progestins Are Inefficacious for Endometriosis-Associated Pain?
    Reproductive sciences (Thousand Oaks, Calif.), 2018, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Desogestrel; Endometriosis

2018
Norethindrone acetate versus extended-cycle oral contraceptive (Seasonique
    European journal of obstetrics, gynecology, and reproductive biology, 2018, Volume: 222

    Topics: Adult; Contraceptives, Oral, Synthetic; Drug Combinations; Endometriosis; Ethinyl Estradiol; Female;

2018
Shifting from Oral Contraceptives to Norethisterone Acetate, or Vice Versa, because of Drug Intolerance: Does the Change Benefit Women with Endometriosis?
    Gynecologic and obstetric investigation, 2018, Volume: 83, Issue:3

    Topics: Adult; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Drug Hypersensitivity; Drug Substituti

2018
Surgical versus low-dose progestin treatment for endometriosis-associated severe deep dyspareunia II: effect on sexual functioning, psychological status and health-related quality of life.
    Human reproduction (Oxford, England), 2013, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Cohort Studies; Depression; Dyspareunia; Endometriosis; Female; Humans; Laparosco

2013
Norethisterone acetate versus norethisterone acetate combined with letrozole for the treatment of ovarian endometriotic cysts: a patient preference study.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 174

    Topics: Adult; Aromatase Inhibitors; Drug Therapy, Combination; Dysmenorrhea; Dyspareunia; Endometriosis; Fe

2014
Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis: a before and after study.
    Fertility and sterility, 2016, Volume: 105, Issue:3

    Topics: Adult; Cost-Benefit Analysis; Drug Costs; Drug Substitution; Endometriosis; Female; Humans; Nandrolo

2016
Analysis of Adherence, Persistence, and Surgery Among Endometriosis Patients Treated with Leuprolide Acetate Plus Norethindrone Acetate Add-Back Therapy.
    Journal of managed care & specialty pharmacy, 2016, Volume: 22, Issue:5

    Topics: Adult; Bone Density; Drug Therapy, Combination; Endometriosis; Estrogens; Female; Gonadotropin-Relea

2016
Progestin suppressed inflammation and cell viability of tumor necrosis factor-α-stimulated endometriotic stromal cells.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2016, Volume: 76, Issue:4

    Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Microenvironment; Cytokines; Endometrio

2016
Progestin suppressed inflammation and cell viability of tumor necrosis factor-α-stimulated endometriotic stromal cells.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2016, Volume: 76, Issue:4

    Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Microenvironment; Cytokines; Endometrio

2016
Progestin suppressed inflammation and cell viability of tumor necrosis factor-α-stimulated endometriotic stromal cells.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2016, Volume: 76, Issue:4

    Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Microenvironment; Cytokines; Endometrio

2016
Progestin suppressed inflammation and cell viability of tumor necrosis factor-α-stimulated endometriotic stromal cells.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2016, Volume: 76, Issue:4

    Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Microenvironment; Cytokines; Endometrio

2016
Hepatic Adenomas in Adolescents and Young Women with Endometriosis Treated with Norethindrone Acetate.
    Journal of pediatric and adolescent gynecology, 2017, Volume: 30, Issue:3

    Topics: Adenoma; Adolescent; Adult; Contraceptives, Oral, Hormonal; Endometriosis; Ethinyl Estradiol; Female

2017
Norethisterone acetate in the treatment of colorectal endometriosis: a pilot study.
    Human reproduction (Oxford, England), 2010, Volume: 25, Issue:1

    Topics: Adult; Colonic Diseases; Endometriosis; Female; Humans; Norethindrone; Norethindrone Acetate; Pain;

2010
Add-back therapy use and its impact on LA persistence in patients with endometriosis.
    Current medical research and opinion, 2010, Volume: 26, Issue:3

    Topics: Adult; Contraceptives, Oral, Synthetic; Databases, Factual; Endometriosis; Estrogens; Female; Gonado

2010
Letrozole and norethisterone acetate in colorectal endometriosis.
    European journal of obstetrics, gynecology, and reproductive biology, 2010, Volume: 150, Issue:2

    Topics: Abdominal Pain; Aromatase Inhibitors; Colonic Diseases; Diarrhea; Drug Therapy, Combination; Dyspare

2010
Endometriosis presenting with hemorrhagic ascites.
    Archives of gynecology and obstetrics, 2011, Volume: 283, Issue:6

    Topics: Ascites; CA-125 Antigen; Contraceptives, Oral, Synthetic; Diagnostic Imaging; Endometriosis; Female;

2011
Oral contraceptives and endometriosis.
    Human reproduction (Oxford, England), 2011, Volume: 26, Issue:6

    Topics: Contraceptives, Oral; Endometriosis; Female; Humans; Norethindrone; Norethindrone Acetate; Recurrenc

2011
Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms.
    Journal of pediatric and adolescent gynecology, 2012, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Contraceptives, Oral, Synthetic; Endometriosis; Female; Humans; Metrorrhagia; Nor

2012
Bone density in adolescents treated with a GnRH agonist and add-back therapy for endometriosis.
    Journal of pediatric and adolescent gynecology, 2007, Volume: 20, Issue:5

    Topics: Absorptiometry, Photon; Adolescent; Adult; Bone Density; Cohort Studies; Endometriosis; Female; Gona

2007
Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study.
    Obstetrics and gynecology, 1998, Volume: 91, Issue:5 Pt 1

    Topics: Drug Therapy, Combination; Endometriosis; Estrogens, Conjugated (USP); Female; Humans; Leuprolide; N

1998
Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study.
    Obstetrics and gynecology, 1998, Volume: 91, Issue:5 Pt 1

    Topics: Drug Therapy, Combination; Endometriosis; Estrogens, Conjugated (USP); Female; Humans; Leuprolide; N

1998
Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study.
    Obstetrics and gynecology, 1998, Volume: 91, Issue:5 Pt 1

    Topics: Drug Therapy, Combination; Endometriosis; Estrogens, Conjugated (USP); Female; Humans; Leuprolide; N

1998
Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study.
    Obstetrics and gynecology, 1998, Volume: 91, Issue:5 Pt 1

    Topics: Drug Therapy, Combination; Endometriosis; Estrogens, Conjugated (USP); Female; Humans; Leuprolide; N

1998