norethindrone acetate has been researched along with Endometrial Neoplasms in 6 studies
norethisterone acetate : A 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.
Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both treatments were generally well tolerated, with most adverse events (>90%) being mild to moderate, although minor differences in the tolerability profile were observed between treatments." | 2.72 | Endometrial safety, overall safety and tolerability of transdermal continuous combined hormone replacement therapy over 96 weeks: a randomized open-label study. ( Arguinzoniz, M; Boschitsch, E; Concin, H; De Geyter, C; Ehrenborg, A; Heikkinen, J; Hobson, R; Ibarra de Palacios, P; Samsioe, G; Scheurer, C; Schmidt, G, 2006) |
| " Women who developed this tumor on sequential therapy in general received less than the recommended guidelines for daily dosage and monthly duration of progestin." | 1.29 | Development of endometrial cancer in women on estrogen and progestin hormone replacement therapy. ( Barbuto, DA; Judd, HL; Karlan, BY; Lagasse, LD; Leuchter, RS; McGonigle, KF, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simsek, T | 1 |
| Karakus, C | 1 |
| Trak, B | 1 |
| Oehler, MK | 1 |
| MacKenzie, IZ | 1 |
| Wallwiener, D | 1 |
| Bicknell, R | 1 |
| Rees, MC | 1 |
| Maia, H | 1 |
| Maltez, A | 1 |
| Studard, E | 1 |
| Athayde, C | 1 |
| Coutinho, EM | 1 |
| Samsioe, G | 1 |
| Boschitsch, E | 1 |
| Concin, H | 1 |
| De Geyter, C | 1 |
| Ehrenborg, A | 1 |
| Heikkinen, J | 1 |
| Hobson, R | 1 |
| Arguinzoniz, M | 1 |
| Ibarra de Palacios, P | 1 |
| Scheurer, C | 1 |
| Schmidt, G | 1 |
| McGonigle, KF | 1 |
| Karlan, BY | 1 |
| Barbuto, DA | 1 |
| Leuchter, RS | 1 |
| Lagasse, LD | 1 |
| Judd, HL | 1 |
| Gruber, DM | 1 |
| Wagner, G | 1 |
| Kurz, C | 1 |
| Sator, MO | 1 |
| Huber, JC | 1 |
2 trials available for norethindrone acetate and Endometrial Neoplasms
| Article | Year |
|---|---|
Impact of different hormone replacement therapy regimens on the size of myoma uteri in postmenopausal period: tibolone versus transdermal hormonal replacement system.
Topics: Administration, Cutaneous; Aged; Antineoplastic Agents, Hormonal; Endometrial Neoplasms; Estradiol; | 2002 |
Endometrial safety, overall safety and tolerability of transdermal continuous combined hormone replacement therapy over 96 weeks: a randomized open-label study.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Drug Therapy, Combination; Endometrial | 2006 |
4 other studies available for norethindrone acetate and Endometrial Neoplasms
| Article | Year |
|---|---|
Wnt-7a is upregulated by norethisterone in human endometrial epithelial cells: a possible mechanism by which progestogens reduce the risk of estrogen-induced endometrial neoplasia.
Topics: Cells, Cultured; Endometrial Neoplasms; Endometrium; Epithelial Cells; Estradiol; Female; Gene Expre | 2002 |
Effect of previous hormone replacement therapy on endometrial polyps during menopause.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Case-Control Studies; Endometrial Neoplasms; | 2004 |
Development of endometrial cancer in women on estrogen and progestin hormone replacement therapy.
Topics: Aged; Aged, 80 and over; Biopsy; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endome | 1994 |
Endometrial cancer after combined hormone replacement therapy.
Topics: Adenocarcinoma; Endometrial Neoplasms; Estradiol; Female; Hormone Replacement Therapy; Humans; Middl | 1999 |