nordefrin has been researched along with Muscle Contraction in 12 studies
Nordefrin: A norepinephrine derivative used as a vasoconstrictor agent.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benextramine was equipotent against the imidazoline, clonidine and the thiazoloazepine B-HT920, however, higher concentrations of benextramine were required for an equivalent non-competitive antagonism of the beta-phenethylamine, alpha-methylnoradrenaline." | 1.27 | The action and interaction of beta-phenethylamines and imidazolines on prejunctional alpha 2-adrenoceptors of guinea-pig ileum in the presence of the non-competitive antagonist benextramine. ( Mottram, DR; Thakar, Y, 1984) |
| " Urotensin I diminished the maximum increase in perfusion pressure and shifted the log dose-response curves to the right for all three agonists." | 1.27 | Differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by urotensin I, a selective mesenteric vasodilator peptide. ( Bolt, GR; Itoh, H; Lederis, K; MacCannell, KL, 1987) |
| " Systemic administration of alpha-methyldopa to rats for 15 days shifted the log dose-response curves for all three catecholamines, but not vasopressin or potassium chloride, to the right of all three blood vessel types; the maximal contractile responses to these amines were, however, not affected by chronic treatment with alpha-methyldopa." | 1.25 | Pharmacological effects of alpha-methyldopa, alpha-methylnorepinephrine, and octopamine on rat arteriolar, arterial, and terminal vascular smooth. ( Altura, BM, 1975) |
| " Dose-response curves to norepinephrine were shifted to the left along the log dose axis (enhanced potency) and the maximum degree of contraction that could be elicited was increased." | 1.25 | Influence of temperature and cocaine on responses of the isolated mouse vas deferens to adrenergic amines. ( Bohuski, K; Buckner, CK; Ryan, CF, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nöhammer, C | 1 |
| Brunner, F | 1 |
| Wölkart, G | 1 |
| Staber, PB | 1 |
| Steyrer, E | 1 |
| Gonzalez, FJ | 1 |
| Zechner, R | 1 |
| Hoefler, G | 1 |
| Mottram, DR | 2 |
| Thakar, Y | 1 |
| Colucci, R | 1 |
| Blandizzi, C | 1 |
| Carignani, D | 1 |
| Lazzeri, G | 1 |
| Natale, G | 1 |
| Crema, F | 1 |
| Del Tacca, M | 1 |
| Castillo, EF | 2 |
| Castillo, C | 2 |
| Valencia, I | 2 |
| Hernández, D | 1 |
| Castillo, MC | 1 |
| Frias, S | 1 |
| Bobadilla, RA | 1 |
| Benoit, JN | 1 |
| Bobadilla, RM | 1 |
| Villalon, CM | 1 |
| Vardolov, L | 1 |
| Pennefather, JN | 1 |
| Altura, BM | 1 |
| Buckner, CK | 1 |
| Bohuski, K | 1 |
| Ryan, CF | 1 |
| Waldeck, B | 1 |
| Jeppsson, AB | 1 |
| Widmark, E | 1 |
| Saggar, P | 1 |
| Bolt, GR | 1 |
| Itoh, H | 1 |
| Lederis, K | 1 |
| MacCannell, KL | 1 |
12 other studies available for nordefrin and Muscle Contraction
| Article | Year |
|---|---|
Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle.
Topics: Animals; Body Weight; Cardiomyopathies; Dose-Response Relationship, Drug; Female; Humans; In Vitro T | 2003 |
The action and interaction of beta-phenethylamines and imidazolines on prejunctional alpha 2-adrenoceptors of guinea-pig ileum in the presence of the non-competitive antagonist benextramine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Cystamine; El | 1984 |
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon | 1996 |
The actions of alpha-methylnorepinephrine on the rat aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Dose-Response Rel | 1996 |
Effects of alpha-adrenergic stimuli on mesenteric collecting lymphatics in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Lymphatic System; Male; Mesentery; | 1997 |
alpha-Methylnoradrenaline-induced contractions in rat aorta are mediated via alpha 1D-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Drug Interactions; Endothel | 1997 |
Regional variation in the distribution of alpha-adrenoreceptors in the vas deferens of the rat.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Cocaine; Dopamine; Electric Stimulation; In Vitr | 1976 |
Pharmacological effects of alpha-methyldopa, alpha-methylnorepinephrine, and octopamine on rat arteriolar, arterial, and terminal vascular smooth.
Topics: Administration, Topical; Animals; Aorta, Thoracic; Blood Vessels; Dopamine; Dose-Response Relationsh | 1975 |
Influence of temperature and cocaine on responses of the isolated mouse vas deferens to adrenergic amines.
Topics: Animals; Biogenic Amines; Cocaine; In Vitro Techniques; Male; Methoxamine; Mice; Muscle Contraction; | 1975 |
Partial agonism and functional selectivity: a study on beta-adrenoceptor mediated effects in tracheal, cardiac and skeletal muscle.
Topics: Adrenergic beta-Agonists; Animals; Benzyl Alcohols; Bronchodilator Agents; Carbachol; Ethanolamines; | 1986 |
Cirazoline, an alpha 2-adrenoceptor antagonist in guinea-pig ileum.
Topics: Acetylcholine; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Female; G | 1985 |
Differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by urotensin I, a selective mesenteric vasodilator peptide.
Topics: Animals; Blood Pressure; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; No | 1987 |