nordefrin has been researched along with Blood Pressure, High in 19 studies
Nordefrin: A norepinephrine derivative used as a vasoconstrictor agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The interactions of dopamine, reserpine and methyldopa on blood pressure of normal subjects and of those with essential hypertension were examined." | 9.04 | Interaction of dopamine, methyldopa and reserpine in the sympatho-adrenal system in essential hypertension. ( Abe, K; Aoyagi, H; Chiba, S; Irokawa, N; Kusaka, T; Miyazaki, S; Otsuka, Y; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1976) |
| " The interactions of dopamine, reserpine and methyldopa on blood pressure of normal subjects and of those with essential hypertension were examined." | 5.04 | Interaction of dopamine, methyldopa and reserpine in the sympatho-adrenal system in essential hypertension. ( Abe, K; Aoyagi, H; Chiba, S; Irokawa, N; Kusaka, T; Miyazaki, S; Otsuka, Y; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1976) |
| "A clinically significant interaction between epinephrine or levonordefrin with nonselective beta-adrenergic blocking agents, although apparently rare in the dental setting, is potentially serious and can lead to significant hypertension with a concomitant reflex bradycardia." | 4.86 | Beta-adrenergic blocking agents and dental vasoconstrictors. ( Giannakopoulos, H; Hersh, EV, 2010) |
| " The simultaneous application of alpha-methyldopa (2 g/day) in 13 patients with primary hypertension did not disturb the fluorimetric estimation of catecholamines." | 3.65 | [An improved trihydroxyindole method for the determination of urinary catecholamines]. ( Werner, U, 1975) |
| "Propranolol is a commonly used drug; of new and refilled prescriptions, it ranked no." | 1.27 | Hypertensive response to levonordefrin in a patient receiving propranolol: report of case. ( Mito, RS; Yagiela, JA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hersh, EV | 1 |
| Giannakopoulos, H | 1 |
| You, JS | 1 |
| Hu, SY | 1 |
| Xia, DS | 1 |
| Karas, M | 1 |
| Larochelle, P | 1 |
| LeBlanc, RA | 1 |
| Dubé, B | 1 |
| Nadeau, R | 1 |
| Champlain, Jd | 1 |
| Kunos, G | 1 |
| Farsang, C | 1 |
| Ramirez-Gonzales, MD | 1 |
| Ruffolo, RR | 1 |
| Yaden, EL | 1 |
| Waddell, JE | 1 |
| Jackman, GP | 1 |
| Oddie, CJ | 1 |
| Skews, H | 1 |
| Bobik, A | 1 |
| Niwa, M | 1 |
| Kawano, T | 1 |
| Fujita, Y | 1 |
| Maemura, S | 1 |
| Ozaki, M | 1 |
| El-Mas, MM | 1 |
| Abdel-Rahman, AA | 1 |
| Werner, U | 1 |
| van Zwieten, AP | 1 |
| Zandberg, P | 2 |
| de Jong, W | 2 |
| Versteeg, DH | 1 |
| Palkovits, M | 1 |
| Abe, K | 1 |
| Aoyagi, H | 1 |
| Yasujima, M | 1 |
| Miyazaki, S | 1 |
| Kusaka, T | 1 |
| Seino, M | 1 |
| Otsuka, Y | 1 |
| Irokawa, N | 1 |
| Chiba, S | 1 |
| Sakurai, Y | 1 |
| Saito, K | 1 |
| Yoshinaga, K | 1 |
| Henning, M | 1 |
| Finch, L | 1 |
| Hersom, A | 1 |
| Hicks, P | 1 |
| Goulet, JP | 2 |
| Pérusse, R | 2 |
| Turcotte, JY | 2 |
| Mito, RS | 1 |
| Yagiela, JA | 1 |
| Pearson, AC | 1 |
| Labovitz, AJ | 1 |
| Kern, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 2%-Mepivacaine With Two Different Vasoconstrictors; 1:20.000 Levonordefrin or 1:100.000 Epinephrin for Local Anesthesia in Third Molar Surgery: A Comparative Randomized Clinical Trial[NCT02603198] | 30 participants (Anticipated) | Interventional | 2014-08-31 | Active, not recruiting | |||
| Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies[NCT03182777] | 31 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| Occurrence of Heart Arrhythmia During Restorative Dental Procedure Under Local Anesthesia , in Heart Failure Pacients. A Double-blind Study[NCT02228083] | 70 participants (Anticipated) | Interventional | 2014-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nordefrin and Blood Pressure, High
| Article | Year |
|---|---|
Beta-adrenergic blocking agents and dental vasoconstrictors.
Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions; | 2010 |
Beta-adrenergic blocking agents and dental vasoconstrictors.
Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions; | 2010 |
Beta-adrenergic blocking agents and dental vasoconstrictors.
Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions; | 2010 |
Beta-adrenergic blocking agents and dental vasoconstrictors.
Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions; | 2010 |
Central sympathetic transmitters and hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Cardiac Output; Cats; Clonidine; Dihydroxyphenylalanine; Dog | 1975 |
Contraindications to vasoconstrictors in dentistry: Part III. Pharmacologic interactions.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthesia, Local; Antidepressive Ag | 1992 |
Contraindications to vasoconstrictors in dentistry: Part I. Cardiovascular diseases.
Topics: Anesthesia, Dental; Anesthesia, Local; Angina, Unstable; Arrhythmias, Cardiac; Cardiovascular Diseas | 1992 |
Contraindications to vasoconstrictors in dentistry: Part I. Cardiovascular diseases.
Topics: Anesthesia, Dental; Anesthesia, Local; Angina, Unstable; Arrhythmias, Cardiac; Cardiovascular Diseas | 1992 |
Contraindications to vasoconstrictors in dentistry: Part I. Cardiovascular diseases.
Topics: Anesthesia, Dental; Anesthesia, Local; Angina, Unstable; Arrhythmias, Cardiac; Cardiovascular Diseas | 1992 |
Contraindications to vasoconstrictors in dentistry: Part I. Cardiovascular diseases.
Topics: Anesthesia, Dental; Anesthesia, Local; Angina, Unstable; Arrhythmias, Cardiac; Cardiovascular Diseas | 1992 |
1 trial available for nordefrin and Blood Pressure, High
| Article | Year |
|---|---|
Interaction of dopamine, methyldopa and reserpine in the sympatho-adrenal system in essential hypertension.
Topics: Adult; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Hypertension; Methyldopa; | 1976 |
14 other studies available for nordefrin and Blood Pressure, High
| Article | Year |
|---|---|
[Further study on the indexes of auxiliary laboratory diagnosis in the syndrome of hyperactivity of liver-yang].
Topics: Adult; Diagnosis, Differential; Epinephrine; Female; Humans; Hypertension; Male; Medicine, Chinese T | 2002 |
Attenuation of autonomic nervous system functions in hypertensive patients at rest and during orthostatic stimulation.
Topics: Adolescent; Adult; Age Factors; Aged; Autonomic Nervous System; Blood Pressure; Electrocardiography; | 2008 |
beta-Endorphin: possible involvement in the antihypertensive effect of central alpha-receptor activation.
Topics: Adrenergic alpha-Agonists; Animals; Brain Stem; Clonidine; Disease Models, Animal; Endorphins; Hyper | 1981 |
Stereochemical requirements of alpha-2 adrenergic receptors.
Topics: Animals; Aorta; Blood Pressure; Dopamine; Guinea Pigs; Hypertension; Male; Molecular Conformation; N | 1982 |
High-performance liquid chromatographic determination of plasma catecholamines during alpha-methyldopa therapy.
Topics: Animals; Catecholamines; Chromatography, High Pressure Liquid; Epinephrine; Humans; Hypertension; Me | 1984 |
[Alpha-methyldopa and brain monoamines].
Topics: Animals; Antihypertensive Agents; Biotransformation; Brain; Catecholamines; Dihydroxyphenylalanine; | 1982 |
Ethanol selectively counteracts hypotension evoked by central I(1)-imidazoline but not alpha2-adrenergic receptor activation in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Ethanol; Heart Rate; Hypertension; Imidazoline Receptors; | 1998 |
[An improved trihydroxyindole method for the determination of urinary catecholamines].
Topics: Chromatography, Ion Exchange; Copper; Epinephrine; Humans; Hydrogen-Ion Concentration; Hypertension; | 1975 |
Antihypertensive action of clonidine (Catapresan).
Topics: Animals; Blood Pressure; Bradycardia; Brain Stem; Cats; Clonidine; Depression, Chemical; Drug Evalua | 1977 |
Hypotensive response in spontaneously hypertensive rats following microinjection of alpha-methylnoradrenaline in the caudal brain-stem.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Medulla Oblongata; Microinjections; Neural Pathwa | 1979 |
Brain-stem structures and catecholamines in the control of arterial blood pressure in the rat.
Topics: Animals; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hype | 1976 |
Studies on the hypotensive action of alpha-methyldopamine.
Topics: Animals; Blood Pressure; Cats; Deoxyepinephrine; Depression, Chemical; Desipramine; Dopamine; Drug I | 1975 |
Hypertensive response to levonordefrin in a patient receiving propranolol: report of case.
Topics: Adult; Anesthesia, Dental; Blood Pressure; Drug Interactions; Female; Humans; Hypertension; Mepivaca | 1988 |
Accelerated hypertension complicated by myocardial infarction after use of a local anesthetic/vasoconstrictor preparation.
Topics: Anesthetics, Local; Humans; Hypertension; Male; Mepivacaine; Middle Aged; Myocardial Infarction; Nor | 1987 |