nordazepam has been researched along with Muscle Spasticity in 3 studies
Nordazepam: An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
nordazepam : A 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight patients with spasticity or rigidity were given placebo or active substance; first in loading doses for 2 days, then 5 mg every 12 h for a total of 10 days." | 2.66 | Effect of clorazepate in spasticity and rigidity: a quantitative study of reflexes and plasma concentrations. ( Dietrichson, P; Lossius, R; Lunde, PK, 1985) |
| "Dogs, surgically implanted with a chronic gastric fistula, were chronically dosed with N-desmethyldiazepam (32 mg/kg/day) in four divided doses to attain N-desmethyldiazepam plasma levels comparable to those observed in dogs dependent on diazepam (60 mg/kg/day)." | 1.27 | N-desmethyldiazepam physical dependence in dogs. ( Martin, WR; McNicholas, LF; Pruitt, TA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lossius, R | 2 |
| Dietrichson, P | 2 |
| Lunde, PK | 2 |
| McNicholas, LF | 1 |
| Martin, WR | 1 |
| Pruitt, TA | 1 |
1 trial available for nordazepam and Muscle Spasticity
| Article | Year |
|---|---|
Effect of clorazepate in spasticity and rigidity: a quantitative study of reflexes and plasma concentrations.
Topics: Adult; Aged; Anti-Anxiety Agents; Brain Diseases; Clorazepate Dipotassium; Female; Humans; Kinetics; | 1985 |
2 other studies available for nordazepam and Muscle Spasticity
| Article | Year |
|---|---|
Effect of diazepam and desmethyldiazepam in spasticity and rigidity. A quantitative study of reflexes and plasma concentrations.
Topics: Adult; Diazepam; Female; Humans; Injections, Intravenous; Male; Middle Aged; Muscle Rigidity; Muscle | 1980 |
N-desmethyldiazepam physical dependence in dogs.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazep | 1985 |