Page last updated: 2024-10-25

nordazepam and Clasp-Knife Spasticity

nordazepam has been researched along with Clasp-Knife Spasticity in 3 studies

Nordazepam: An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
nordazepam : A 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety.

Research Excerpts

ExcerptRelevanceReference
"Eight patients with spasticity or rigidity were given placebo or active substance; first in loading doses for 2 days, then 5 mg every 12 h for a total of 10 days."2.66Effect of clorazepate in spasticity and rigidity: a quantitative study of reflexes and plasma concentrations. ( Dietrichson, P; Lossius, R; Lunde, PK, 1985)
"Dogs, surgically implanted with a chronic gastric fistula, were chronically dosed with N-desmethyldiazepam (32 mg/kg/day) in four divided doses to attain N-desmethyldiazepam plasma levels comparable to those observed in dogs dependent on diazepam (60 mg/kg/day)."1.27N-desmethyldiazepam physical dependence in dogs. ( Martin, WR; McNicholas, LF; Pruitt, TA, 1985)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lossius, R2
Dietrichson, P2
Lunde, PK2
McNicholas, LF1
Martin, WR1
Pruitt, TA1

Trials

1 trial available for nordazepam and Clasp-Knife Spasticity

ArticleYear
Effect of clorazepate in spasticity and rigidity: a quantitative study of reflexes and plasma concentrations.
    Acta neurologica Scandinavica, 1985, Volume: 71, Issue:3

    Topics: Adult; Aged; Anti-Anxiety Agents; Brain Diseases; Clorazepate Dipotassium; Female; Humans; Kinetics;

1985

Other Studies

2 other studies available for nordazepam and Clasp-Knife Spasticity

ArticleYear
Effect of diazepam and desmethyldiazepam in spasticity and rigidity. A quantitative study of reflexes and plasma concentrations.
    Acta neurologica Scandinavica, 1980, Volume: 61, Issue:6

    Topics: Adult; Diazepam; Female; Humans; Injections, Intravenous; Male; Middle Aged; Muscle Rigidity; Muscle

1980
N-desmethyldiazepam physical dependence in dogs.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazep

1985