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nordazepam and Cirrhosis, Liver

nordazepam has been researched along with Cirrhosis, Liver in 2 studies

Nordazepam: An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
nordazepam : A 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety.

Research Excerpts

ExcerptRelevanceReference
" The accumulation of DD after multiple dosage could be explained by the fact that it is formed faster from D than it is eliminated."2.64Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease. ( Antonin, KH; Bieck, PR; Brügel, H; Klotz, U, 1977)
" Plasma concentrations of DZ and its major metabolite desmethyldiazepam (DMDZ) were measured daily during the period of dosing and in the 7-day washout period that followed."1.27Repeated diazepam dosing in cirrhotic patients: cumulation and sedation. ( Eckardt, B; Greenblatt, DJ; Harmatz, JS; Ochs, HR; Shader, RI, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ochs, HR1
Greenblatt, DJ1
Eckardt, B1
Harmatz, JS1
Shader, RI1
Klotz, U1
Antonin, KH1
Brügel, H1
Bieck, PR1

Trials

1 trial available for nordazepam and Cirrhosis, Liver

ArticleYear
Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:4

    Topics: Adult; Biological Availability; Biotransformation; Clinical Trials as Topic; Diazepam; Half-Life; He

1977

Other Studies

1 other study available for nordazepam and Cirrhosis, Liver

ArticleYear
Repeated diazepam dosing in cirrhotic patients: cumulation and sedation.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:4

    Topics: Adult; Diazepam; Half-Life; Humans; Hypnotics and Sedatives; Kinetics; Liver Cirrhosis; Male; Middle

1983