nordazepam has been researched along with Anxiety Disorders in 14 studies
Nordazepam: An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
nordazepam : A 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety.
Anxiety Disorders: Persistent and disabling ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazepam, 5 mg, was devoid of adverse psychomotor effects, but diazepam, 10 mg, impaired tracking and divided attention task performance in patients and volunteers alike." | 2.65 | Psychomotor effects of diazepam in anxious patients and healthy volunteers. ( Brendle, A; Erwin, CW; Linnoila, M; Simpson, D, 1983) |
| "It is important to understand both the kinetic and the dynamic implications of dosing TCAs and BZs in the elderly, for whom these drugs are frequently prescribed." | 2.37 | Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics. ( Cutler, NR; Narang, PK, 1984) |
| " Serum nordiazepam is a more consistent index of dosage after chronic therapy than serum diazepam because it has a longer elimination half-time." | 1.27 | Value of serum diazepam and nordiazepam measurements in anxious patients. ( Dawling, S; Flanagan, RJ; Moreton, K; Riley, P; Treasaden, I; Tyrer, P, 1984) |
| " Significant relationships were found between the clinical effect and the plasma concentrations of D and DD, respectively; a curvilinear relationship resulted if the dosage was disregarded, but within the individual dosage groups the relationship was found to be linear." | 1.27 | Diazepam and desmethyldiazepam plasma concentrations in chronic anxious outpatients. ( Case, WG; Dixon, R; Downing, RW; Fridman, R; Rickels, K, 1984) |
| " The dosage remained the same for all patients during the 28 days of the experiment." | 1.27 | [Efficacy and kinetics of chlorazepate administered to anxious patients in a single daily dose]. ( Adamkiewicz, L; Duguay, R; Le Lorier, J; Messier, R; Rochefort, JG; Viguié, F, 1985) |
| " The findings of modest diazepam dose and plasma concentration (mean=324 ng/ml) and of a trend toward a positive correlation between anxiety level and both dose and plasma level suggest inadequate dosage as a more likely explanation for the subjects' continued anxiety." | 1.26 | Chronic diazepam treatment in psychiatric outpatients. ( Battey, YW; Greenblatt, DJ; Laughren, TP, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nicholson, AN | 1 |
| Tyrer, P | 1 |
| Treasaden, I | 1 |
| Moreton, K | 1 |
| Riley, P | 1 |
| Flanagan, RJ | 1 |
| Dawling, S | 1 |
| Linnoila, M | 1 |
| Erwin, CW | 1 |
| Brendle, A | 1 |
| Simpson, D | 1 |
| Fabre, LF | 1 |
| Johnson, PA | 1 |
| Greenblatt, DJ | 2 |
| Rickels, K | 2 |
| Case, WG | 1 |
| Downing, RW | 1 |
| Dixon, R | 1 |
| Fridman, R | 1 |
| Winokur, A | 1 |
| Cutler, NR | 1 |
| Narang, PK | 1 |
| Bowden, CL | 1 |
| Fisher, JG | 1 |
| Laughren, TP | 1 |
| Battey, YW | 1 |
| Rocca, P | 2 |
| Fonzo, V | 1 |
| Scotta, M | 1 |
| Zanalda, E | 2 |
| Ravizza, L | 2 |
| Beoni, AM | 1 |
| Eva, C | 1 |
| Ferrero, P | 1 |
| Andreoli, V | 1 |
| Maffei, F | 1 |
| Montanaro, N | 1 |
| Morandini, G | 1 |
| Duguay, R | 1 |
| Le Lorier, J | 1 |
| Rochefort, JG | 1 |
| Messier, R | 1 |
| Viguié, F | 1 |
| Adamkiewicz, L | 1 |
| Bareggi, SR | 1 |
| Nielsen, NP | 1 |
| Leva, S | 1 |
| Pirola, R | 1 |
| Zecca, L | 1 |
| Lorini, M | 1 |
1 review available for nordazepam and Anxiety Disorders
| Article | Year |
|---|---|
Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.
Topics: Adipose Tissue; Adult; Aged; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorde | 1984 |
6 trials available for nordazepam and Anxiety Disorders
| Article | Year |
|---|---|
Psychomotor effects of diazepam in anxious patients and healthy volunteers.
Topics: Adult; Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Nordazep | 1983 |
Drowsiness sedation levels in anxious neurotic outpatients.
Topics: Adolescent; Adult; Anxiety Disorders; Arousal; Clinical Trials as Topic; Double-Blind Method; Female | 1984 |
Withdrawal responses to abrupt discontinuation of desmethyldiazepam.
Topics: Acute Disease; Adult; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Feeding and | 1984 |
Relationship of diazepam serum level to antianxiety effects.
Topics: Adult; Anxiety Disorders; Chromatography, Gas; Chromatography, High Pressure Liquid; Diazepam; Femal | 1982 |
Paroxetine efficacy in the treatment of generalized anxiety disorder.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorde | 1997 |
Double-blind cross-over clinical comparison of two 2'-chloro benzodiazepines: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one (chlordesmethyldiazepam) versus 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Brief Psychiatric Rating Scale; Clinical Trials | 1977 |
7 other studies available for nordazepam and Anxiety Disorders
| Article | Year |
|---|---|
[Anxiolytics in man: studies on sleep and performance (author's transl)].
Topics: Anti-Anxiety Agents; Anxiety Disorders; Arousal; Attention; Benzodiazepines; Benzodiazepinones; Clob | 1982 |
Value of serum diazepam and nordiazepam measurements in anxious patients.
Topics: Adult; Aged; Anxiety Disorders; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Mi | 1984 |
Diazepam and desmethyldiazepam plasma concentrations in chronic anxious outpatients.
Topics: Adult; Anxiety Disorders; Chronic Disease; Diazepam; Female; Humans; Male; Middle Aged; Nordazepam | 1984 |
Chronic diazepam treatment in psychiatric outpatients.
Topics: Adult; Aged; Ambulatory Care; Anxiety Disorders; Chronic Disease; Diazepam; Humans; Male; Middle Age | 1982 |
Peripheral benzodiazepine receptor messenger RNA is decreased in lymphocytes of generalized anxiety disorder patients.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Female; Follow-Up Studies; Humans; L | 1998 |
[Efficacy and kinetics of chlorazepate administered to anxious patients in a single daily dose].
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Clorazepate Dipotassium; Female; Humans; Kinetics; Ma | 1985 |
Age-related multiple-dose pharmacokinetics and anxiolytic effects of delorazepam (chlordesmethyldiazepam).
Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Diazepam; Female; Human | 1986 |