nordazepam has been researched along with Aging in 8 studies
Nordazepam: An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
nordazepam : A 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is important to understand both the kinetic and the dynamic implications of dosing TCAs and BZs in the elderly, for whom these drugs are frequently prescribed." | 2.37 | Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics. ( Cutler, NR; Narang, PK, 1984) |
| "To evaluate changes in the pharmacokinetic disposition of diazepam in foals from 4 to 84 days of age." | 1.30 | Age-related changes in the pharmacokinetic disposition of diazepam in foals. ( Court, MH; Greenblatt, DJ; Norman, WM, 1997) |
| "The elimination half-life of chlordiazepoxide and diazepam increases with age, and this may cause prolongation of action after a single dose and delayed accumulation on multiple dosing in elderly patients." | 1.26 | [Pharmacokinetic of benzodiazepines in old age]. ( Vozeh, S, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sacre, L | 1 |
| Ali, SM | 1 |
| Villa, A | 1 |
| Jouffroy, R | 1 |
| Raphalen, JH | 1 |
| Garnier, R | 1 |
| Baud, FJ | 1 |
| Vozeh, S | 1 |
| Cutler, NR | 1 |
| Narang, PK | 1 |
| Norman, WM | 1 |
| Court, MH | 1 |
| Greenblatt, DJ | 1 |
| Kanto, J | 1 |
| Sellman, R | 1 |
| Haataja, M | 1 |
| Hurme, P | 1 |
| Klotz, U | 1 |
| Müller-Seydlitz, P | 1 |
| Bareggi, SR | 1 |
| Nielsen, NP | 1 |
| Leva, S | 1 |
| Pirola, R | 1 |
| Zecca, L | 1 |
| Lorini, M | 1 |
| Swift, CG | 1 |
| Ewen, JM | 1 |
| Clarke, P | 1 |
| Stevenson, IH | 1 |
1 review available for nordazepam and Aging
| Article | Year |
|---|---|
Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.
Topics: Adipose Tissue; Adult; Aged; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorde | 1984 |
7 other studies available for nordazepam and Aging
| Article | Year |
|---|---|
Toxicodynetics in nordiazepam and oxazepam overdoses.
Topics: Adolescent; Adult; Aging; Central Nervous System Depressants; Child; Child, Preschool; Drug Overdose | 2017 |
[Pharmacokinetic of benzodiazepines in old age].
Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Half-Life; Humans; Lorazepam; M | 1981 |
Age-related changes in the pharmacokinetic disposition of diazepam in foals.
Topics: Adjuvants, Anesthesia; Aging; Animals; Diazepam; Female; Half-Life; Horses; Male; Metabolic Clearanc | 1997 |
Plasma and urine concentrations of diazepam and its metabolites in children, adults and in diazepam-intoxicated patients.
Topics: Adult; Aging; Biotransformation; Child; Creatinine; Diazepam; Female; Humans; Infant; Infant, Newbor | 1978 |
Altered elimination of desmethyldiazepam in the elderly.
Topics: Adult; Aged; Aging; Diazepam; Half-Life; Humans; Liver; Nordazepam; Time Factors | 1979 |
Age-related multiple-dose pharmacokinetics and anxiolytic effects of delorazepam (chlordesmethyldiazepam).
Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Diazepam; Female; Human | 1986 |
Responsiveness to oral diazepam in the elderly: relationship to total and free plasma concentrations.
Topics: Adult; Aged; Aging; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedati | 1985 |