Compounds > norcantharidin
Page last updated: 2024-08-26

norcantharidin and Colorectal Neoplasms

norcantharidin has been researched along with Colorectal Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Herrmann, P; Ishfaq, MA; Schöpe, PC; Shoemaker, RH; Smith, J; Stein, U; Walther, W; Zinnow, V1
Hu, C; Hua, Y; Yang, Y; Zhang, S; Zhong, Y1
Chang, WM; Chen, YJ; Jang, YH; Kuo, CD; Lee, CY; Liao, HF; Liu, YW1
Chang, FR; Chen, MF; Hu, DN; Tsai, CH; Wu, YC; Yang, PY1
Fan, Z; Hou, F; Li, D; Li, Q; Liu, J; Liu, M; Yu, T; Zhou, L1
Cai, J; Chen, X; Chen, Z; Ji, Q; Li, Q; Liu, X; Qiu, Y; Sun, J; Zhang, L; Zhu, H1
Chen, YJ; Ho, LT; Kuo, CD; Liao, HF; Liu, TY; Shieh, CJ; Tsai, TH1
Chen, YJ; Kuo, CD; Liao, HF; Tsai, YM; Wang, GS; Yu, CC1
Jiang, Y; Kan, B; Lei, S; Liu, JY; Lu, Y; Luo, F; Mao, YQ; Peng, F; Tian, L; Wang, GS; Wang, QR; Wei, YQ; Yang, L; Zhao, X; Zou, LQ1

Other Studies

9 other study(ies) available for norcantharidin and Colorectal Neoplasms

ArticleYear
Cantharidin and Its Analogue Norcantharidin Inhibit Metastasis-Inducing Genes S100A4 and MACC1.
    International journal of molecular sciences, 2023, Jan-07, Volume: 24, Issue:2

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Cantharidin; Colorectal Neoplasms; Humans; Neoplasms; S100 Calcium-Binding Protein A4; Trans-Activators; Transcription Factors

2023
NCTD elicits proapoptotic and antiglycolytic effects on colorectal cancer cells via modulation of Fam46c expression and inhibition of ERK1/2 signaling.
    Molecular medicine reports, 2020, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Female; Gene Knockdown Techniques; Glycolysis; Humans; Male; MAP Kinase Signaling System; Middle Aged; Nucleotidyltransferases

2020
A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells.
    Chemico-biological interactions, 2009, Oct-30, Volume: 181, Issue:3

    Topics: Base Sequence; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Colorectal Neoplasms; DNA Primers; Down-Regulation; Electrophoretic Mobility Shift Assay; Humans; Matrix Metalloproteinase 9; Neoplasm Metastasis; Reverse Transcriptase Polymerase Chain Reaction; Sp1 Transcription Factor; Transcription, Genetic

2009
Involvement of caspase and MAPK activities in norcantharidin-induced colorectal cancer cell apoptosis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:3

    Topics: Aged; Antineoplastic Agents; Apoptosis; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Caspases; Cell Line, Tumor; Colorectal Neoplasms; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fluorescent Dyes; Histones; Humans; Indoles; Male; Middle Aged; Mitogen-Activated Protein Kinases

2010
Norcantharidin anti-angiogenesis activity possibly through an endothelial cell pathway in human colorectal cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Colorectal Neoplasms; Human Umbilical Vein Endothelial Cells; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2012
Norcantharidin inhibits tumor angiogenesis via blocking VEGFR2/MEK/ERK signaling pathways.
    Cancer science, 2013, Volume: 104, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Human Umbilical Vein Endothelial Cells; Humans; Male; MAP Kinase Signaling System; Mice; Mice, SCID; Neoplasm Invasiveness; Neovascularization, Pathologic; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2013
Inhibitory effect of norcantharidin, a derivative compound from blister beetles, on tumor invasion and metastasis in CT26 colorectal adenocarcinoma cells.
    Anti-cancer drugs, 2005, Volume: 16, Issue:3

    Topics: Adenocarcinoma; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Colorectal Neoplasms; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Tumor Cells, Cultured

2005
Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells.
    Anti-cancer drugs, 2008, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Animals; Anoikis; Antimetabolites; Antineoplastic Agents; Blotting, Western; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Bromodeoxyuridine; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Data Interpretation, Statistical; Enzyme Activation; Flow Cytometry; JNK Mitogen-Activated Protein Kinases; Mice; Monocytes

2008
Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: involvement of the CD95 receptor/ligand.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:4

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Caspase 8; Caspase 9; Caspases; Colorectal Neoplasms; Fas Ligand Protein; Humans; Membrane Glycoproteins; Tumor Cells, Cultured; Up-Regulation

2002