Page last updated: 2024-09-02

norbuprenorphine and Respiratory Insufficiency

norbuprenorphine has been researched along with Respiratory Insufficiency in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (11.11)	18.2507
2000's	2 (22.22)	29.6817
2010's	6 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baillie, S; Bell, J; Bogdanowicz, K; Knight, A; Reed, K; Strang, J	1
Baccino, E; Bardy, G; Cathala, P; Eiden, C; Mathieu, O; Petit, P	1
Chevillard, L; Cohier, C; Mégarbane, B; Risède, P; Roussel, O; Salle, S	1
Baud, FJ; Mégarbane, B; Vodovar, D	1
Brown, SM; Holtzman, M; Kharasch, ED; Kim, T	1
Alhaddad, H; Baud, FJ; Besengez, C; Chiadmi, F; Cisternino, S; Declèves, X; Mégarbane, B; Risède, P; Scherrmann, JM; Schlatter, J; Smirnova, M; Tournier, N	1
Baud, FJ; Borron, SW; Gueye, PN; Marie, N; Mégarbane, B; Monier, C; Noble, F; Pirnay, S; Risède, P	1
Baud, FJ; Borron, SW; Descatoire, V; Hreiche, R; Mégarbane, B; Milan, N; Monier, C; Pessayre, D; Pirnay, S; Risède, P	1
Iga, T; Kotaki, H; Nishitateno, K; Ohtani, M; Sawada, Y	1

Trials

1 trial(s) available for norbuprenorphine and Respiratory Insufficiency

Article	Year
Norbuprenorphine and respiratory depression: Exploratory analyses with new lyophilized buprenorphine and sublingual buprenorphine . International journal of clinical pharmacology and therapeutics, 2018, Volume: 56, Issue:2 Topics: Administration, Sublingual; Analgesics, Opioid; Biological Availability; Biotransformation; Buprenorphine; Drug Compounding; Freeze Drying; Humans; Lung; Opiate Substitution Treatment; Opioid-Related Disorders; Respiration; Respiratory Insufficiency; Risk Factors; Solubility; Tablets; Treatment Outcome	2018

Article

Year

Norbuprenorphine and respiratory depression: Exploratory analyses with new lyophilized buprenorphine and sublingual buprenorphine .

International journal of clinical pharmacology and therapeutics, 2018, Volume: 56, Issue:2

Topics: Administration, Sublingual; Analgesics, Opioid; Biological Availability; Biotransformation; Buprenorphine; Drug Compounding; Freeze Drying; Humans; Lung; Opiate Substitution Treatment; Opioid-Related Disorders; Respiration; Respiratory Insufficiency; Risk Factors; Solubility; Tablets; Treatment Outcome

2018

Other Studies

8 other study(ies) available for norbuprenorphine and Respiratory Insufficiency

Article	Year
An unusual case of death probably triggered by the association of buprenorphine at therapeutic dose with ethanol and benzodiazepines and with very low norbuprenorphine level. Journal of forensic sciences, 2015, Volume: 60 Suppl 1 Topics: Adult; Analgesics, Opioid; Benzodiazepines; Bile; Buprenorphine; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Ethanol; Fatal Outcome; Forensic Toxicology; Gastrointestinal Contents; Humans; Male; Respiratory Insufficiency; Tandem Mass Spectrometry	2015
Editor's Highlight: Neurorespiratory Effects of Buprenorphine and Ethanol in Combination: A Mechanistic Study of Drug-Drug Interactions in the Rat. Toxicological sciences : an official journal of the Society of Toxicology, 2017, Volume: 155, Issue:2 Topics: Analgesics, Opioid; Animals; Buprenorphine; Drug Interactions; Ethanol; Gas Chromatography-Mass Spectrometry; Male; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Respiration; Respiratory Insufficiency	2017
Fatalities in relation to buprenorphine snorting and ethanol co-ingestion: mechanisms of toxicity. Forensic science international, 2011, Apr-15, Volume: 207, Issue:1-3 Topics: Administration, Intranasal; Alcohol Drinking; Animals; Buprenorphine; Forensic Toxicology; Humans; Narcotics; Respiratory Insufficiency	2011
Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active. Anesthesiology, 2011, Volume: 115, Issue:6 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Buprenorphine; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Female; Glucuronides; Humans; Male; Mice; Motor Activity; Nociceptin Receptor; Pain; Pain Measurement; Plethysmography, Whole Body; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Respiratory Insufficiency; Tidal Volume	2011
Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood-brain barrier in mice. Critical care medicine, 2012, Volume: 40, Issue:12 Topics: Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blood-Brain Barrier; Buprenorphine; Drug Interactions; Female; France; Mice; Mice, Knockout; Plethysmography; Respiratory Insufficiency	2012
Buprenorphine is protective against the depressive effects of norbuprenorphine on ventilation. Toxicology and applied pharmacology, 2006, May-01, Volume: 212, Issue:3 Topics: Animals; Arteries; Blood Gas Analysis; Buprenorphine; Dose-Response Relationship, Drug; Drug Antagonism; Lethal Dose 50; Lung; Male; Narcotic Antagonists; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiratory Insufficiency	2006
Dexamethasone hepatic induction in rats subsequently treated with high dose buprenorphine does not lead to respiratory depression. Toxicology and applied pharmacology, 2006, Dec-15, Volume: 217, Issue:3 Topics: Animals; Buprenorphine; Cytochrome P-450 CYP3A; Dexamethasone; Enzyme Induction; Glucocorticoids; Injections, Intraperitoneal; Liver; Male; Narcotics; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Respiratory Insufficiency	2006
Kinetics of respiratory depression in rats induced by buprenorphine and its metabolite, norbuprenorphine. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1 Topics: Analgesics, Opioid; Animals; Buprenorphine; Carbon Dioxide; Infusions, Intravenous; Injections, Intravenous; Male; Naloxone; Rats; Rats, Wistar; Receptors, Opioid; Respiration; Respiratory Insufficiency	1997