Compounds > nonoxynol
Page last updated: 2024-08-18

nonoxynol and Inflammation

nonoxynol has been researched along with Inflammation in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Howie, SEM; MacPherson, H; Norman, JE; Pavlidis, I; Sammut Demarco, G; Spiller, OB; Stock, SJ1
Chandra, N; Doncel, GF; Fichorova, RN; Mendonca, K; Murray, R; Yamamoto, HS1
Chen, JC; Giudice, LC; Greenblatt, RM; Hilton, JF; Irwin, JC; Johnson, B; Shacklett, BL; Shanmugasundaram, U; Smith-McCune, K1
Alt, C; D'Andrea, A; Dousman, L; Fujita, N; Harrison, T; Matsukawa, A; Mirsalis, J; Shayesteh, S; Shew, K; Tran, TT1
Anderson, DJ; Ayehunie, S; Cannon, C; Klausner, M; Larosa, K; Pudney, J1
Cerocchi, OG; Donaghay, MA; Doncel, GF; Joseph, T; Schriver, SD; Zalenskaya, IA1
Bao, R; Cao, Y; Chen, Y; Han, C; He, B; Jiang, S; Li, L; Li, Y; Shi, W; Sun, Y; Yan, H; Yang, J; Yang, Y; Zhang, X; Zhang, Y; Zhong, M; Zhou, D1
Chandra, N; Doncel, GF; Fichorova, RN1
Low-Beer, N1
Betts, K; Chvapil, M; Droegemueller, W; Eskelson, CD; Owen, JA1

Trials

2 trial(s) available for nonoxynol and Inflammation

ArticleYear
Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Administration, Intravaginal; Adult; Anti-HIV Agents; Cellular Microenvironment; Cervix Uteri; Cross-Over Studies; Female; Gels; Humans; Inflammation; Nonoxynol; Phenotype; Placebos; T-Lymphocytes; Transcriptome; Uterus; Young Adult

2015
The role of biopsy in vaginal microbicide development.
    Journal of acquired immune deficiency syndromes (1999), 2004, Volume: 37 Suppl 3

    Topics: Adolescent; Adult; Anti-HIV Agents; Anti-Infective Agents; Biopsy; Colposcopy; Dextrins; Double-Blind Method; Female; HIV Infections; Humans; Inflammation; Middle Aged; Naphthalenesulfonates; Nonoxynol; Polymers; Vagina

2004

Other Studies

8 other study(ies) available for nonoxynol and Inflammation

ArticleYear
Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice.
    Nature communications, 2020, 01-10, Volume: 11, Issue:1

    Topics: Animals; Cell Proliferation; Cervix Uteri; Cytokines; Disease Models, Animal; Female; Humans; Infant, Newborn; Inflammation; Mice; Mice, Inbred C57BL; Nonoxynol; Pregnancy; Pregnancy Complications, Infectious; Ureaplasma

2020
A quantitative multiplex nuclease protection assay reveals immunotoxicity gene expression profiles in the rabbit model for vaginal drug safety evaluation.
    Toxicology and applied pharmacology, 2015, Jun-15, Volume: 285, Issue:3

    Topics: Adenine; Animals; Anti-HIV Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Female; Host-Pathogen Interactions; Immunohistochemistry; Inflammation; Interleukin-1beta; Interleukin-8; Mucous Membrane; Nonoxynol; Nuclease Protection Assays; Oligopeptides; Organophosphonates; Rabbits; Tenofovir; Toll-Like Receptor 4; Transcriptome; Vagina

2015
Increased CCL2 expression and macrophage/monocyte migration during microbicide-induced vaginal irritation.
    Current HIV research, 2009, Volume: 7, Issue:6

    Topics: Animals; Benzalkonium Compounds; Biomarkers; Cell Movement; Chemokine CCL2; Female; HIV; HIV Infections; Humans; Inflammation; Interleukin-1beta; Interleukin-8; Macrophages; Monocytes; Nonoxynol; Rabbits; Surface-Active Agents; Vagina

2009
Development of an in vitro alternative assay method for vaginal irritation.
    Toxicology, 2011, Jan-11, Volume: 279, Issue:1-3

    Topics: Adult; Animal Testing Alternatives; Animals; Benzalkonium Compounds; Cytokines; Drug Evaluation, Preclinical; Electric Impedance; Female; Humans; Inflammation; Inflammation Mediators; Irritants; Mucous Membrane; Nonoxynol; Rabbits; Reproducibility of Results; Toxicity Tests; Vagina

2011
Increased COX-2 expression in human vaginal epithelial cells exposed to nonoxynol-9, a vaginal contraceptive microbicide that failed to protect women from HIV-1 infection.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2011, Volume: 65, Issue:6

    Topics: Anti-Infective Agents; Cell Line, Transformed; Contraceptive Agents, Female; Cyclooxygenase 2; Dinoprostone; Epithelial Cells; Female; HIV Infections; HIV-1; Humans; Immunity, Mucosal; Inflammation; NF-kappa B; Nonoxynol; Oligonucleotide Array Sequence Analysis; Vagina; Virulence

2011
L-selectin and P-selectin are novel biomarkers of cervicovaginal inflammation for preclinical mucosal safety assessment of anti-HIV-1 microbicide.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Adenine; Animals; Anti-Infective Agents; Benzalkonium Compounds; Biomarkers; Carboxymethylcellulose Sodium; Cervix Uteri; Chemokine CCL2; Female; HIV Infections; Inflammation; Interleukin-6; L-Selectin; Mice; Mice, Inbred C57BL; Mucous Membrane; Nonoxynol; Organophosphonates; P-Selectin; Sodium Dodecyl Sulfate; Tenofovir

2012
Preclinical assessment of the proinflammatory potential of microbicide candidates.
    Journal of acquired immune deficiency syndromes (1999), 2004, Volume: 37 Suppl 3

    Topics: Animals; Anti-HIV Agents; Anti-Infective Agents; Cell Line; Cervix Uteri; Cytokines; Drug Evaluation, Preclinical; Female; HIV Infections; Humans; Immunity, Mucosal; In Vitro Techniques; Inflammation; Male; NF-kappa B; Nonoxynol; Rabbits; Safety; Vagina

2004
Studies of nonoxynol-9. I. The effect on the vaginas of rabbits and rats.
    Fertility and sterility, 1980, Volume: 33, Issue:4

    Topics: Animals; Collagen; DNA; Epithelium; Female; Inflammation; Nonoxynol; Polyethylene Glycols; Rabbits; Rats; Spermatocidal Agents; Vagina

1980